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From Substance Use ...
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Brådvik, LouiseLund University,Lunds universitet,Lundbystudien,Forskargrupper vid Lunds universitet,The Lundby Study,Lund University Research Groups
(författare)
From Substance Use Disorders in Life to Autopsy Findings : A Combined Case-Record and Medico-Legal Study
- Artikel/kapitelEngelska2019
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Nummerbeteckningar
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LIBRIS-ID:oai:lup.lub.lu.se:e39e9506-a8d8-49f0-b6f9-274a882a519f
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https://lup.lub.lu.se/record/e39e9506-a8d8-49f0-b6f9-274a882a519fURI
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https://doi.org/10.3390/ijerph16050801DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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Ämneskategori:ref swepub-contenttype
Anmärkningar
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Objectives: Several studies have shown mortality and suicide risk in substance use disorders, and autopsy findings with respect to the used substances. However, there seems to be a gap in the knowledge about substances misused in life and at death at the within-person level. Methods: All consecutive, autopsied patients during 1993 to 1997, who had been in contact with the Addiction Centre in Malmö from 1968, were investigated (365 subjects). Drug misuse in the long-term course noted in case records was related to autopsy findings. Self-inflicted death (suicide/undetermined suicide/accidental overdose) was compared with natural death. Results: Benzodiazepine misuse was associated with a high risk of autopsy findings of the substance in suicide and death of undetermined intent. It was also associated among non-misusers, but less so. An alcohol level above 1‰ was found more often in self-inflicted death. Prescription opioids at autopsy were mainly found in self-inflicted death among non-misusers. Heroin misuse was related to overdose. Central nervous system stimulants (CNS-S) and cannabis were rarely found in self-inflicted death among previous misusers. The overlap between depression in life and antidepressants at death was low. Conclusions: Benzodiazepines and alcohol seem to disinhibit suicidal tendencies. Suicide risk among users of cannabis and CNS-S may be related to other risk factors than acute use. Implications for suicide prevention are discussed.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Löwenhielm, PeterLund University,Lunds universitet,Rättsmedicin,Forskargrupper vid Lunds universitet,Forensic Medicine,Lund University Research Groups(Swepub:lu)rmed-plo
(författare)
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Frank, ArneLund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine(Swepub:lu)alk-afr
(författare)
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Berglund, MatsLund University,Lunds universitet,Enheten för klinisk beroendeforskning,Forskargrupper vid Lunds universitet,Clinical addiction research unit,Lund University Research Groups(Swepub:lu)alk-mbe
(författare)
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LundbystudienForskargrupper vid Lunds universitet
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:International Journal of Environmental Research and Public Health: MDPI AG16:51660-4601
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