SwePub
Sök i LIBRIS databas

  Extended search

L773:0021 9630 OR L773:1469 7610
 

Search: L773:0021 9630 OR L773:1469 7610 > Autism spectrum dis...

  • Lundström, SebastianGothenburg University,Göteborgs universitet,Gillbergcentrum,Centrum för etik, juridik och mental hälsa,Gillberg Neuropsychiatry Centre,Centre for Ethics, Law, and Mental Health (author)

Autism spectrum disorders and coexisting disorders in a nationwide Swedish twin study

  • Article/chapterEnglish2015

Publisher, publication year, extent ...

  • 2014-10-03
  • Stockholm :Wiley,2015

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:e8bcc286-4f3b-4544-9846-c961572e31cd
  • ISSN:0021-9630
  • 10616/45048hdl
  • https://lup.lub.lu.se/record/4697451URI
  • https://doi.org/10.1111/jcpp.12329DOI
  • http://hdl.handle.net/10616/45048URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:131302459URI
  • https://gup.ub.gu.se/publication/203725URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • Background: Evidence from twin and molecular genetic studies is accumulating that Autism Spectrum Disorder (ASD) shares substantial etiological factors with other disorders. This is mirrored in clinical practice where ASD without coexisting disorders is rare. The present study aims to examine the range of coexisting disorders in ASD in a genetically informative cohort. Methods: Parents of all Swedish 9-year-old twins born between 1992 and 2001 (n = 19,130) underwent a telephone interview designed to screen for child psychiatric disorders, including ASD. To ensure full coverage of child psychiatric disorders, data were also retrieved from population-based health registers. We investigated the coexistence of eight psychiatric disorders known to coexist with ASDs in probands and their co-twins. Results: Half of the individuals with ASDs (50.3%) had four or more coexisting disorders and only 4% did not have any concomitant disorder. The ‘healthy co-twin’ in ASD discordant monozygotic twin pairs was very often (79% of boys and 50% of girls) affected by at least one non-ASD disorder. The corresponding figures for ASD discordant dizygotic twin pairs were significantly lower (46% of males and 30% of females). Conclusions: Detailed phenotypic descriptions including symptoms of problems associated with a wide range of child psychiatric disorders may aid in unraveling the genetic architecture of ASD and should guide the development of intervention strategies addressing each problem type specifically.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Reichenberg, Abraham (author)
  • Melke, Jonas,1971Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för farmakologi,Institute of Neuroscience and Physiology, Department of Pharmacology(Swepub:gu)xmelkj (author)
  • Råstam, MariaLund University,Lunds universitet,Barn- och ungdomspsykiatri,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Child and Adolescent Psychiatry,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:gu)xrasma (author)
  • Kerekes, Nora,1969Gothenburg University,Göteborgs universitet,Centrum för etik, juridik och mental hälsa,Centre for Ethics, Law, and Mental Health(Swepub:gu)xkerno (author)
  • Lichtenstein, PaulKarolinska Institutet (author)
  • Gillberg, Christopher,1950Gothenburg University,Göteborgs universitet,Gillbergcentrum,Gillberg Neuropsychiatry Centre(Swepub:gu)xgilch (author)
  • Anckarsäter, HenrikGothenburg University,Göteborgs universitet,Lund University,Lunds universitet,Rättspsykiatri, Malmö,Forskargrupper vid Lunds universitet,Forensic Psychiatry, Malmö,Lund University Research Groups,Centrum för etik, juridik och mental hälsa,Centre for Ethics, Law, and Mental Health(Swepub:gu)xanche (author)
  • Göteborgs universitetGillbergcentrum (creator_code:org_t)
  • Karolinska Institutet
  • Karolinska Institutet

Related titles

  • In:Journal of Child Psychology and Psychiatry and Allied DisciplinesStockholm : Wiley56:6, s. 702-7100021-96301469-7610

Internet link

Find in a library

To the university's database

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view