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  • Mylrea-Foley, BronachaImperial College London,Queen Charlotte's and Chelsea Hospital (author)

Longitudinal Doppler Assessments in Late Preterm Fetal Growth Restriction

  • Article/chapterEnglish2023

Publisher, publication year, extent ...

  • 2021-11-12
  • Georg Thieme Verlag KG,2023

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:ebb46afd-cc2a-41d0-9be2-4ad7432d7669
  • https://lup.lub.lu.se/record/ebb46afd-cc2a-41d0-9be2-4ad7432d7669URI
  • https://doi.org/10.1055/a-1511-8293DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:148093089URI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • Purpose To assess the longitudinal variation of the ratio of umbilical and cerebral artery pulsatility index (UCR) in late preterm fetal growth restriction (FGR). Materials and Methods A prospective European multicenter observational study included women with a singleton pregnancy, 32 +0-36 +6, at risk of FGR (estimated fetal weight [EFW] or abdominal circumference [AC] <10 th percentile, abnormal arterial Doppler or fall in AC from 20-week scan of >40 percentile points). The primary outcome was a composite of abnormal condition at birth or major neonatal morbidity. UCR was categorized as normal (<0.9) or abnormal (≥0.9). UCR was assessed by gestational age at measurement interval to delivery, and by individual linear regression coefficient in women with two or more measurements. Results 856 women had 2770 measurements; 696 (81%) had more than one measurement (median 3 (IQR 2-4). At inclusion, 63 (7%) a UCR ≥0.9. These delivered earlier and had a lower birth weight and higher incidence of adverse outcome (30% vs. 9%, relative risk 3.2; 95%CI 2.1-5.0) than women with a normal UCR at inclusion. Repeated measurements after an abnormal UCR at inclusion were abnormal again in 67% (95%CI 55-80), but after a normal UCR the chance of finding an abnormal UCR was 6% (95%CI 5-7%). The risk of composite adverse outcome was similar using the first or subsequent UCR values. Conclusion An abnormal UCR is likely to be abnormal again at a later measurement, while after a normal UCR the chance of an abnormal UCR is 5-7% when repeated weekly. Repeated measurements do not predict outcome better than the first measurement, most likely due to the most compromised fetuses being delivered after an abnormal UCR.

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Added entries (persons, corporate bodies, meetings, titles ...)

  • Wolf, HansAcademic Medical Center of University of Amsterdam (AMC) (author)
  • Stampalija, TamaraUniversity of Trieste,Burlo Garofolo Pediatric Institute (author)
  • Lees, ChristophImperial College London,University Hospitals Leuven,Queen Charlotte's and Chelsea Hospital (author)
  • Arabin, B.Humboldt University of Berlin (author)
  • Berger, A.Medical University of Innsbruck (author)
  • Bergman, E.Uppsala University (author)
  • Bhide, A.St George's Hospital, London (author)
  • Bilardo, C. M.Academic Medical Center of University of Amsterdam (AMC) (author)
  • Breeze, A. C.Leeds General Infirmary (author)
  • Brodszki, J.Lund University,Lunds universitet,Obstetrik och gynekologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Obstetrics and Gynaecology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital(Swepub:lu)gyn-jko (author)
  • Calda, P.General University Hospital in Prague (author)
  • Cetin, I.University of Milan (author)
  • Cesari, E.University of Milan (author)
  • Derks, J.Utrecht University (author)
  • Ebbing, C.Haukeland University Hospital (author)
  • Ferrazzi, E.University of Milan (author)
  • Ganzevoort, W.Academic Medical Center of University of Amsterdam (AMC) (author)
  • Frusca, T.University of Parma (author)
  • Gordijn, S. J.University Medical Center Groningen (author)
  • Gyselaers, W. (author)
  • Hecher, K.University Medical Center Hamburg-Eppendorf (author)
  • Klaritsch, P.Medical University of Graz (author)
  • Krofta, L. (author)
  • Lindgren, P.Karolinska University Hospital (author)
  • Lobmaier, S. M.Klinikum rechts der Isar (author)
  • Marlow, N.University College London (author)
  • Maruotti, G. M.University of Naples Federico II (author)
  • Mecacci, F.University of Florence (author)
  • Myklestad, K.St. Olav’s University Hospital (author)
  • Napolitano, R.University College London,University College London Hospital (author)
  • Prefumo, F.University of Brescia (author)
  • Raio, L.Bern University Hospital (author)
  • Richter, J.University Hospitals Leuven (author)
  • Sande, R. K.Stavanger University Hospital (author)
  • Thornton, J.University of Nottingham (author)
  • Valensise, H.University of Rome Tor Vergata (author)
  • Visser, G. H.A.Haukeland University Hospital (author)
  • Wee, L.Princess Alexandra Hospital NHS Trust (author)
  • Imperial College LondonQueen Charlotte's and Chelsea Hospital (creator_code:org_t)

Related titles

  • In:Ultraschall in der Medizin: Georg Thieme Verlag KG44:1, s. 56-670172-4614
  • In:Ultraschall in der Medizin - European Journal of Ultrasound: Georg Thieme Verlag KG44:1, s. 56-671438-8782

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