Search: WFRF:(Dos Santos Silva Graciela) >
Synthesis and chara...
Synthesis and characterization of FeIII(μ-OH)ZnII complexes : Effects of a second coordination sphere and increase in the chelate ring size on the hydrolysis of a phosphate diester and DNA
-
- Silva, Graciela Aparecida Dos Santos (author)
- Federal University of Santa Catarina
-
- Amorim, André Luiz (author)
- Federal University of Santa Catarina
-
- Souza, Bernardo De (author)
- Federal University of Santa Catarina
-
show more...
-
- Gabriel, Philipe (author)
- Federal University of Santa Catarina
-
- Terenzi, Hernán (author)
- Federal University of Santa Catarina
-
- Nordlander, Ebbe (author)
- Lund University,Lunds universitet,Kemisk fysik,Enheten för fysikalisk och teoretisk kemi,Kemiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Chemical Physics,Physical and theoretical chemistry,Department of Chemistry,Departments at LTH,Faculty of Engineering, LTH
-
- Neves, Ademir (author)
- Federal University of Santa Catarina
-
- Peralta, Rosely A. (author)
- Federal University of Santa Catarina
-
show less...
-
(creator_code:org_t)
- 2017
- 2017
- English 15 s.
-
In: Dalton Transactions. - : Royal Society of Chemistry (RSC). - 1477-9226 .- 1477-9234. ; 46:34, s. 11380-11394
- Related links:
-
http://dx.doi.org/10...
-
show more...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- The synthesis and characterization of three ligands and their respective heterobinuclear FeIIIZnII complexes were carried out, with the goal of mimicking the active site of purple acid phosphatases (PAPs). The ligand 2-hydroxy-3-(((2-hydroxy-5-methyl-3-(((2-(pyridin-2-yl)ethyl)(pyridin-2-ylmethyl)amino)methyl)benzyl)(pyridin-2ylmethyl)amino)methyl)-5-methylbenzaldehyde (H2L2) was synthesized and its complex (FeIIIZnIIL2) was used as a basis for comparison with similar complexes previously published in the literature. Subsequent modifications were conducted in the aldehyde group, where 1,2-ethanediamine and 1,4-diaminobutane were used as side chain derivatives. The compounds FeIIIZnIIL2 (1), FeIIIZnIIL2-et (2) and FeIIIZnIIL2-but (3) were characterized by spectroscopic methods (infrared and UV-Vis) and ESI-MS spectrometry. Theoretical calculations were performed to provide insights into the complex structures with FeIIIZnII structures. The hydrolytic activity was analyzed both with the model substrate 2,4-BDNPP and with DNA catalyzed by complexes 1, 2 and 3.
Subject headings
- NATURVETENSKAP -- Kemi -- Oorganisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Inorganic Chemistry (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
To the university's database