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  • Gerdtsson, AxelKarolinska Institutet,Karolinska Institute,Department of Clinical Science, Intervention and Technology, Division of Urology, Karolinska Institutet, Stockholm, Sweden; Department of Urology, Skåne University Hospital, Malmö, Sweden (författare)

Surgical Complications in Postchemotherapy Retroperitoneal Lymph Node Dissection for Nonseminoma Germ Cell Tumour : A Population-based Study from the Swedish Norwegian Testicular Cancer Group

  • Artikel/kapitelEngelska2020

Förlag, utgivningsår, omfång ...

  • Elsevier BV,2020
  • 8 s.

Nummerbeteckningar

  • LIBRIS-ID:oai:lup.lub.lu.se:ee776eb2-3046-48e9-ac22-184ef847096e
  • https://lup.lub.lu.se/record/ee776eb2-3046-48e9-ac22-184ef847096eURI
  • https://doi.org/10.1016/j.euo.2019.08.002DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-397707URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:145311450URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-174309URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

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Klassifikation

  • Ämneskategori:art swepub-publicationtype
  • Ämneskategori:ref swepub-contenttype

Anmärkningar

  • Funding agency: Gosta Jonsson Foundation 
  • BACKGROUND: Reports on perioperative complications after postchemotherapy retroperitoneal lymph node dissection (PC-RPLND) for nonseminoma germ cell tumour (NSGCT) are from experienced single centres, with a lack of population-based studies. OBJECTIVE: To assess the complications of bilateral and unilateral PC-RPLND. DESIGN, SETTING, AND PARTICIPANTS: A prospective, population-based, observational multicentre study included all patients with NSGCT who underwent PC-RPLND in Norway and Sweden during 2007-2014. Of a total of 318 patients, 87 underwent bilateral PC-RPLND and 231 underwent unilateral PC-RPLND. The median follow-up was 6 yr. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Bilateral and unilateral PC-RPLND were compared for the outcomes of intra- and postoperative complications (graded by Clavien-Dindo) and retrograde ejaculation (with or without nerve-sparing surgery). Complications were reported as absolute counts and percentages. The χ2 test was used for comparisons. RESULTS AND LIMITATIONS: The incidence of intraoperative complications was higher for bilateral PC-RPLND than for unilateral PC-RPLND (14% vs 4.3%, p = 0.003), with ureteral injury as the most frequent reported complication (2% of the patients). Postoperative complications were more common after bilateral than after unilateral PC-RPLND (45% vs 25%, p = 0.001) with Clavien ≥3b reported in 8.3% and 2.2%, respectively (p = 0.009). Lymphatic leakage was the most common complication occurring in 11% of the patients. Retrograde ejaculation occurred more frequently after bilateral than after unilateral surgery (59% vs 32%, p < 0.001). Limitations of the study include reporting of retrograde ejaculation, which was based on a chart review. CONCLUSIONS: Intra- and postoperative complications including retrograde ejaculation are more frequent after bilateral PC-RPLND than after unilateral PC-RPLND. PATIENT SUMMARY: Lymph node dissection in patients with testicular cancer puts them at risk of complications. In this study, we present the complications after lymph node dissection.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Håkansson, UlfGHP Gastro Center Skåne,Gastrocenter, Lund, Sweden(Swepub:lu)kir-uha (författare)
  • Törnblom, MagnusKarolinska Institute,Department of Clinical Science and Education, Section of Urology, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden; Department of Surgery, Visby County Hospital, Visby, Sweden (författare)
  • Jancke, GeorgeLinköping University Hospital,Region Östergötland, Urologiska kliniken i Östergötland(Swepub:liu)geoja67 (författare)
  • Negaard, Helene F.S.Department of Oncology, Oslo University Hospital, Oslo, Norway (författare)
  • Glimelius, Ingrid,1975-Karolinska Institutet,Uppsala universitet,Uppsala University,Experimentell och klinisk onkologi,Department of Immunology, Genetics and Pathology, Unit of Clinical and Experimental Oncology, Uppsala University, Sweden(Swepub:uu)inggl846 (författare)
  • Halvorsen, DagDepartment of Urology, St. Olavs University Hospital, Trondheim, Norway (författare)
  • Karlsdóttir, ÁsaDepartment of Oncology, Haukeland University Hospital, Bergen, Norway (författare)
  • Haugnes, Hege SagstuenDepartment of Oncology, University Hospital of North Norway, Tromsø, Norway; Department of Clinical Medicine, UIT-The Arctic University of Norway, Tromsø, Norway (författare)
  • Andreassen, Kristine EngenDepartment of Oncology, Oslo University Hospital, Oslo, Norway (författare)
  • Larsen, Signe MelsenDepartment of Urology, Oslo University Hospital, Oslo, Norway (författare)
  • Holmberg, GöranDepartment of Urology, Sahlgrenska University Hospital, Gothenburg, Sweden (författare)
  • Wahlqvist, RolfDepartment of Urology, Oslo University Hospital, Oslo, Norway (författare)
  • Tandstad, TorgrimSt. Olav’s University Hospital,The Cancer Clinic, St; Department of Clinical and Molecular Medicine, The Norwegian University of Science and Technology, Trondheim, Norway (författare)
  • Cohn-Cedermark, GabriellaKarolinska Institutet,Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden; PO Bäckencancer, Karolinska University Hospital, Stockholm, Sweden (författare)
  • Ståhl, OlofLund University,Lunds universitet,Medicinsk onkologi,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medical oncology,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Oncology, Skåne University Hospital, Lund, Sweden; Department of Clinical Sciences, Lund University, Lund, Sweden(Swepub:lu)kir-ost (författare)
  • Kjellman, AndersKarolinska Institutet,Department of Clinical Science, Intervention and Technology, Division of Urology, Karolinska Institutet, Stockholm, Sweden; Department of Urology, Pelvic Cancer, Karolinska University Hospital, Stockholm, Sweden (författare)
  • Karolinska InstituteDepartment of Clinical Science, Intervention and Technology, Division of Urology, Karolinska Institutet, Stockholm, Sweden; Department of Urology, Skåne University Hospital, Malmö, Sweden (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:European Urology Oncology: Elsevier BV3:3, s. 382-3892588-9311

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