Search: onr:"swepub:oai:lup.lub.lu.se:ef7fef6e-7181-4590-884f-b7ba0fd17d8f" >
Drug use disorder a...
-
Dahlman, DisaLund University,Lunds universitet,Enheten för klinisk beroendeforskning,Forskargrupper vid Lunds universitet,Clinical addiction research unit,Lund University Research Groups,Region Skåne
(author)
Drug use disorder and risk of incident and fatal breast cancer : a nationwide epidemiological study
- Article/chapterEnglish2021
Publisher, publication year, extent ...
-
2020-11-06
-
Springer Science and Business Media LLC,2021
Numbers
-
LIBRIS-ID:oai:lup.lub.lu.se:ef7fef6e-7181-4590-884f-b7ba0fd17d8f
-
https://lup.lub.lu.se/record/ef7fef6e-7181-4590-884f-b7ba0fd17d8fURI
-
https://doi.org/10.1007/s10549-020-05998-4DOI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:art swepub-publicationtype
-
Subject category:ref swepub-contenttype
Notes
-
Purpose: Breast cancer is one of the most common cancer forms in women and it is often detected by screening. However, women with drug use disorders (DUD) are less likely to be reached by screening programs. In this study, we aimed to investigate breast cancer incidence, mortality and stage at time of diagnosis among women with DUD compared to the general female population in Sweden. Methods: We performed a follow-up study based on Swedish national register data for the period January 1997–December 2015. The study was based on 3,838,248 women aged 15–75 years, of whom 50,858 were registered with DUD. Adjusted hazard ratios (HRs) for incident and fatal breast cancer, and cancer stage at time of diagnosis, were calculated for women with and without DUD using Cox regression analysis. Results: DUD was associated with incident breast cancer (HR 1.08, 95% confidence interval [CI] 1.02–1.14, p = 0.0069), fatal breast cancer (HR 1.60, 95% CI 1.42–1.82, p < 0.001), and stage IV breast cancer, i.e. metastasis at diagnosis (HR 2.06, 95% CI 1.44–2.95, p < 0.001). Conclusions: Women with DUD were identified as a risk group for incident, fatal and metastasized breast cancer, which calls for attention from clinicians and policy makers. Cancer screening attendance and other healthcare seeking barriers are likely to affect the risk increase among women who use drugs; however, more research is needed on the underlying mechanisms.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Magnusson, HedvigLund University,Region Skåne
(author)
-
Li, XinjunLund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Family Medicine and Clinical Epidemiology,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Region Skåne(Swepub:lu)med-xul
(author)
-
Sundquist, JanLund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Family Medicine and Clinical Epidemiology,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Shimane University,Region Skåne,Icahn School of Medicine at Mount Sinai(Swepub:lu)med-jsu
(author)
-
Sundquist, KristinaLund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Family Medicine and Clinical Epidemiology,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Shimane University,Icahn School of Medicine at Mount Sinai,Region Skåne(Swepub:lu)med-ksq
(author)
-
Enheten för klinisk beroendeforskningForskargrupper vid Lunds universitet
(creator_code:org_t)
Related titles
-
In:Breast Cancer Research and Treatment: Springer Science and Business Media LLC186:1, s. 199-2070167-68061573-7217
Internet link
Find in a library
To the university's database