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Lifetime alcohol in...
Lifetime alcohol intake, drinking patterns over time and risk of stomach cancer : A pooled analysis of data from two prospective cohort studies
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- Jayasekara, Harindra (författare)
- La Trobe University,University of Melbourne,Cancer Council Victoria
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- MacInnis, Robert J. (författare)
- Cancer Council Victoria,University of Melbourne
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- Lujan-Barroso, Leila (författare)
- L'Hospitalet de Llobregat, Barcelona,Bellvitge University Hospital-IDIBELL,University of Barcelona
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- Mayen-Chacon, Ana Lucia (författare)
- International Agency for Research on Cancer, World Health Organization
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- Cross, Amanda J. (författare)
- Imperial College London
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- Wallner, Bengt, 1962- (författare)
- Umeå universitet,Kirurgi,Norrland University Hospital
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- Palli, Domenico (författare)
- Institute for Cancer Research, Prevention and Clinical Network (ISPRO)
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- Ricceri, Fulvio (författare)
- University of Turin,Azienda Sanitaria Locale Torino 3
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- Pala, Valeria (författare)
- Istituto Nazionale dei Tumori
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- Panico, Salvatore (författare)
- University of Naples Federico II
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- Tumino, Rosario (författare)
- Provincial Health Authority (ASP) Ragusa
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- Kühn, Tilman (författare)
- German Cancer Research Centre
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- Kaaks, Rudolf (författare)
- German Cancer Research Centre
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- Tsilidis, Kostas (författare)
- Imperial College London
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- Sánchez, Maria Jose (författare)
- University of Granada,CIBER Epidemiology and Public Health (CIBERESP),Andalusian School Of Public Health (EASP)
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- Amiano, Pilar (författare)
- CIBER Epidemiology and Public Health (CIBERESP),Biodonostia Health Research Institute
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- Ardanaz, Eva (författare)
- Navarre Public Health Institute (ISPN),Health Research Institute of Navarra (IDISNA),CIBER Epidemiology and Public Health (CIBERESP)
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- Chirlaque López, María Dolores (författare)
- CIBER Epidemiology and Public Health (CIBERESP),University of Murcia
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- Merino, Susana (författare)
- Public Health Directorate
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- Rothwell, Joseph A. (författare)
- University of Paris-Saclay,Versailles Saint-Quentin-en-Yvelines University,L'Hospitalet de Llobregat, Barcelona,Bellvitge University Hospital-IDIBELL
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- Boutron-Ruault, Marie Christine (författare)
- Institut Gustave Roussy,University of Paris-Saclay,Versailles Saint-Quentin-en-Yvelines University
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- Severi, Gianluca (författare)
- Institut Gustave Roussy,University of Florence,University of Paris-Saclay
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- Sternby, Hanna (författare)
- Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups
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- Sonestedt, Emily (författare)
- Lund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups
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- Bueno-de-Mesquita, Bas (författare)
- National Institute for Public Health and the Environment (RIVM)
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- Boeing, Heiner (författare)
- University of Potsdam
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- Travis, Ruth (författare)
- University of Oxford
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- Sandanger, Torkjel M. (författare)
- UiT The Arctic University of Norway, Tromsø
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- Trichopoulou, Antonia (författare)
- Hellenic Health Foundation, Athens
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- Karakatsani, Anna (författare)
- Hellenic Health Foundation, Athens,National and Kapodistrian University of Athens,Attikon University Hospital
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- Peppa, Eleni (författare)
- Hellenic Health Foundation, Athens
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- Tjønneland, Anne (författare)
- Danish Cancer Society,University of Copenhagen
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- Yang, Yi (författare)
- Cancer Council Victoria,University of Melbourne
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- Hodge, Allison M. (författare)
- Cancer Council Victoria,University of Melbourne
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- Mitchell, Hazel (författare)
- University of New South Wales
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- Haydon, Andrew (författare)
- Alfred Hospital
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- Room, Robin (författare)
- Stockholms universitet,Stockholm University,La Trobe University, Australia,Centrum för socialvetenskaplig alkohol- och drogforskning (SoRAD),University of Melbourne,Cancer Council Victoria
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- Hopper, John L. (författare)
- University of Melbourne
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- Weiderpass, Elisabete (författare)
- International Agency for Research on Cancer, World Health Organization
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- Gunter, Marc J. (författare)
- International Agency for Research on Cancer, World Health Organization
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- Riboli, Elio (författare)
- Imperial College London
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- Giles, Graham G. (författare)
- Cancer Council Victoria,University of Melbourne,Monash University
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- Milne, Roger L. (författare)
- Monash University,Cancer Council Victoria,University of Melbourne
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- Agudo, Antonio (författare)
- L'Hospitalet de Llobregat, Barcelona,Bellvitge University Hospital-IDIBELL
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- English, Dallas R. (författare)
- University of Melbourne,Cancer Council Victoria
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- Ferrari, Pietro (författare)
- International Agency for Research on Cancer, World Health Organization
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(creator_code:org_t)
- 2021-02-22
- 2021
- Engelska.
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Ingår i: International Journal of Cancer. - : Wiley. - 0020-7136 .- 1097-0215. ; 148:11, s. 2759-2773
- Relaterad länk:
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http://dx.doi.org/10... (free)
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visa fler...
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https://onlinelibrar...
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Alcohol consumption is causally linked to several cancers but the evidence for stomach cancer is inconclusive. In our study, the association between long-term alcohol intake and risk of stomach cancer and its subtypes was evaluated. We performed a pooled analysis of data collected at baseline from 491 714 participants in the European Prospective Investigation into Cancer and Nutrition and the Melbourne Collaborative Cohort Study. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated for incident stomach cancer in relation to lifetime alcohol intake and group-based life course intake trajectories, adjusted for potential confounders including Helicobacter pylori infection. In all, 1225 incident stomach cancers (78% noncardia) were diagnosed over 7 094 637 person-years; 984 in 382 957 study participants with lifetime alcohol intake data (5 455 507 person-years). Although lifetime alcohol intake was not associated with overall stomach cancer risk, we observed a weak positive association with noncardia cancer (HR = 1.03, 95% CI: 1.00-1.06 per 10 g/d increment), with a HR of 1.50 (95% CI: 1.08-2.09) for ≥60 g/d compared to 0.1 to 4.9 g/d. A weak inverse association with cardia cancer (HR = 0.93, 95% CI: 0.87-1.00) was also observed. HRs of 1.48 (95% CI: 1.10-1.99) for noncardia and 0.51 (95% CI: 0.26-1.03) for cardia cancer were observed for a life course trajectory characterized by heavy decreasing intake compared to light stable intake (Phomogeneity =.02). These associations did not differ appreciably by smoking or H pylori infection status. Limiting alcohol use during lifetime, particularly avoiding heavy use during early adulthood, might help prevent noncardia stomach cancer. Heterogeneous associations observed for cardia and noncardia cancers may indicate etiologic differences.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- cardia cancer
- EPIC
- lifetime alcohol intake
- MCCS
- noncardia cancer
- stomach cancer
- EPIC
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Jayasekara, Hari ...
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MacInnis, Robert ...
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Lujan-Barroso, L ...
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Mayen-Chacon, An ...
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Cross, Amanda J.
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Wallner, Bengt, ...
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visa fler...
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Palli, Domenico
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Ricceri, Fulvio
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Pala, Valeria
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Panico, Salvator ...
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Tumino, Rosario
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Kühn, Tilman
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Kaaks, Rudolf
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Tsilidis, Kostas
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Sánchez, Maria J ...
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Amiano, Pilar
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Ardanaz, Eva
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Chirlaque López, ...
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Merino, Susana
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Rothwell, Joseph ...
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Boutron-Ruault, ...
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Severi, Gianluca
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Sternby, Hanna
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Sonestedt, Emily
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Bueno-de-Mesquit ...
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Boeing, Heiner
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Travis, Ruth
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Sandanger, Torkj ...
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Trichopoulou, An ...
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Karakatsani, Ann ...
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Peppa, Eleni
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Tjønneland, Anne
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Yang, Yi
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Hodge, Allison M ...
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Mitchell, Hazel
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Haydon, Andrew
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Room, Robin
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Hopper, John L.
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Weiderpass, Elis ...
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Gunter, Marc J.
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Riboli, Elio
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Giles, Graham G.
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Milne, Roger L.
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Agudo, Antonio
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English, Dallas ...
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Ferrari, Pietro
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Cancer och onkol ...
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kirurgi
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Lunds universitet
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Umeå universitet
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Stockholms universitet