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Lifetime alcohol in...
Lifetime alcohol intake, drinking patterns over time and risk of stomach cancer : A pooled analysis of data from two prospective cohort studies
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- Jayasekara, Harindra (författare)
- La Trobe University,Cancer Council Victoria,University of Melbourne
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- MacInnis, Robert J. (författare)
- University of Melbourne,Cancer Council Victoria
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- Lujan-Barroso, Leila (författare)
- L'Hospitalet de Llobregat, Barcelona,Bellvitge University Hospital-IDIBELL,University of Barcelona
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- Mayen-Chacon, Ana Lucia (författare)
- International Agency for Research on Cancer, World Health Organization
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- Cross, Amanda J. (författare)
- Imperial College London
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- Wallner, Bengt, 1962- (författare)
- Umeå universitet,Kirurgi,Norrland University Hospital
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- Palli, Domenico (författare)
- Institute for Cancer Research, Prevention and Clinical Network (ISPRO)
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- Ricceri, Fulvio (författare)
- Azienda Sanitaria Locale Torino 3,University of Turin
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- Pala, Valeria (författare)
- Istituto Nazionale dei Tumori
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- Panico, Salvatore (författare)
- University of Naples Federico II
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- Tumino, Rosario (författare)
- Provincial Health Authority (ASP) Ragusa
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- Kühn, Tilman (författare)
- German Cancer Research Centre
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- Kaaks, Rudolf (författare)
- German Cancer Research Centre
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- Tsilidis, Kostas (författare)
- Imperial College London
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- Sánchez, Maria Jose (författare)
- CIBER Epidemiology and Public Health (CIBERESP),Andalusian School Of Public Health (EASP),University of Granada
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- Amiano, Pilar (författare)
- Biodonostia Health Research Institute,CIBER Epidemiology and Public Health (CIBERESP)
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- Ardanaz, Eva (författare)
- Health Research Institute of Navarra (IDISNA),Navarre Public Health Institute (ISPN),CIBER Epidemiology and Public Health (CIBERESP)
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- Chirlaque López, María Dolores (författare)
- University of Murcia,CIBER Epidemiology and Public Health (CIBERESP)
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- Merino, Susana (författare)
- Public Health Directorate
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- Rothwell, Joseph A. (författare)
- Versailles Saint-Quentin-en-Yvelines University,University of Paris-Saclay,Bellvitge University Hospital-IDIBELL,L'Hospitalet de Llobregat, Barcelona
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- Boutron-Ruault, Marie Christine (författare)
- Institut Gustave Roussy,University of Paris-Saclay,Versailles Saint-Quentin-en-Yvelines University
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- Severi, Gianluca (författare)
- University of Florence,University of Paris-Saclay,Institut Gustave Roussy
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- Sternby, Hanna (författare)
- Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups
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- Sonestedt, Emily (författare)
- Lund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups
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- Bueno-de-Mesquita, Bas (författare)
- National Institute for Public Health and the Environment (RIVM)
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- Boeing, Heiner (författare)
- University of Potsdam
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- Travis, Ruth (författare)
- University of Oxford
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- Sandanger, Torkjel M. (författare)
- UiT The Arctic University of Norway, Tromsø
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- Trichopoulou, Antonia (författare)
- Hellenic Health Foundation, Athens
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- Karakatsani, Anna (författare)
- Attikon University Hospital,Hellenic Health Foundation, Athens,National and Kapodistrian University of Athens
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- Peppa, Eleni (författare)
- Hellenic Health Foundation, Athens
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- Tjønneland, Anne (författare)
- University of Copenhagen,Danish Cancer Society
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- Yang, Yi (författare)
- Cancer Council Victoria,University of Melbourne
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- Hodge, Allison M. (författare)
- Cancer Council Victoria,University of Melbourne
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- Mitchell, Hazel (författare)
- University of New South Wales
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- Haydon, Andrew (författare)
- Alfred Hospital
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- Room, Robin (författare)
- Stockholms universitet,Stockholm University,La Trobe University, Australia,Centrum för socialvetenskaplig alkohol- och drogforskning (SoRAD),University of Melbourne,Cancer Council Victoria
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- Hopper, John L. (författare)
- University of Melbourne
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- Weiderpass, Elisabete (författare)
- International Agency for Research on Cancer, World Health Organization
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- Gunter, Marc J. (författare)
- International Agency for Research on Cancer, World Health Organization
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- Riboli, Elio (författare)
- Imperial College London
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- Giles, Graham G. (författare)
- Monash University,Cancer Council Victoria,University of Melbourne
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- Milne, Roger L. (författare)
- University of Melbourne,Cancer Council Victoria,Monash University
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- Agudo, Antonio (författare)
- Bellvitge University Hospital-IDIBELL,L'Hospitalet de Llobregat, Barcelona
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- English, Dallas R. (författare)
- University of Melbourne,Cancer Council Victoria
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- Ferrari, Pietro (författare)
- International Agency for Research on Cancer, World Health Organization
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(creator_code:org_t)
- 2021-02-22
- 2021
- Engelska.
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Ingår i: International Journal of Cancer. - : Wiley. - 0020-7136 .- 1097-0215. ; 148:11, s. 2759-2773
- Relaterad länk:
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http://dx.doi.org/10... (free)
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visa fler...
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https://onlinelibrar...
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Alcohol consumption is causally linked to several cancers but the evidence for stomach cancer is inconclusive. In our study, the association between long-term alcohol intake and risk of stomach cancer and its subtypes was evaluated. We performed a pooled analysis of data collected at baseline from 491 714 participants in the European Prospective Investigation into Cancer and Nutrition and the Melbourne Collaborative Cohort Study. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated for incident stomach cancer in relation to lifetime alcohol intake and group-based life course intake trajectories, adjusted for potential confounders including Helicobacter pylori infection. In all, 1225 incident stomach cancers (78% noncardia) were diagnosed over 7 094 637 person-years; 984 in 382 957 study participants with lifetime alcohol intake data (5 455 507 person-years). Although lifetime alcohol intake was not associated with overall stomach cancer risk, we observed a weak positive association with noncardia cancer (HR = 1.03, 95% CI: 1.00-1.06 per 10 g/d increment), with a HR of 1.50 (95% CI: 1.08-2.09) for ≥60 g/d compared to 0.1 to 4.9 g/d. A weak inverse association with cardia cancer (HR = 0.93, 95% CI: 0.87-1.00) was also observed. HRs of 1.48 (95% CI: 1.10-1.99) for noncardia and 0.51 (95% CI: 0.26-1.03) for cardia cancer were observed for a life course trajectory characterized by heavy decreasing intake compared to light stable intake (Phomogeneity =.02). These associations did not differ appreciably by smoking or H pylori infection status. Limiting alcohol use during lifetime, particularly avoiding heavy use during early adulthood, might help prevent noncardia stomach cancer. Heterogeneous associations observed for cardia and noncardia cancers may indicate etiologic differences.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- cardia cancer
- EPIC
- lifetime alcohol intake
- MCCS
- noncardia cancer
- stomach cancer
- EPIC
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- art (ämneskategori)
- ref (ämneskategori)
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Jayasekara, Hari ...
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MacInnis, Robert ...
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Lujan-Barroso, L ...
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Mayen-Chacon, An ...
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Cross, Amanda J.
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Wallner, Bengt, ...
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visa fler...
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Palli, Domenico
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Ricceri, Fulvio
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Pala, Valeria
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Panico, Salvator ...
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Tumino, Rosario
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Kühn, Tilman
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Kaaks, Rudolf
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Tsilidis, Kostas
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Sánchez, Maria J ...
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Amiano, Pilar
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Ardanaz, Eva
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Chirlaque López, ...
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Merino, Susana
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Rothwell, Joseph ...
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Boutron-Ruault, ...
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Severi, Gianluca
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Sternby, Hanna
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Sonestedt, Emily
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Bueno-de-Mesquit ...
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Boeing, Heiner
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Travis, Ruth
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Sandanger, Torkj ...
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Trichopoulou, An ...
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Karakatsani, Ann ...
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Peppa, Eleni
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Tjønneland, Anne
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Yang, Yi
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Hodge, Allison M ...
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Mitchell, Hazel
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Haydon, Andrew
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Room, Robin
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Hopper, John L.
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Weiderpass, Elis ...
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Gunter, Marc J.
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Riboli, Elio
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Giles, Graham G.
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Milne, Roger L.
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Agudo, Antonio
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English, Dallas ...
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Ferrari, Pietro
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