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2018 Update of the ...
2018 Update of the EULAR recommendations for the management of large vessel vasculitis
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- Hellmich, Bernhard (författare)
- University of Tübingen
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- Agueda, Ana (författare)
- Centro Hospitalar do Baixo Vouga
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- Monti, Sara (författare)
- University of Pavia
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- Buttgereit, Frank (författare)
- Charité - University Medicine Berlin
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- De Boysson, Hubert (författare)
- Centre Hospitalier Universitaire Côte de Nacre
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- Brouwer, Elisabeth (författare)
- University Medical Center Groningen
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- Cassie, Rebecca (författare)
- No affiliation available (private)
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- Cid, Maria Cinta (författare)
- University of Barcelona
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- Dasgupta, Bhaskar (författare)
- Southend Hospital
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- Dejaco, Christian (författare)
- Medical University of Graz
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- Hatemi, Gulen (författare)
- Istanbul University
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- Hollinger, Nicole (författare)
- University of Tübingen
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- Mahr, Alfred (författare)
- Paris Diderot University
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- Mollan, Susan P. (författare)
- University of Birmingham,University Hospitals Birmingham
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- Mukhtyar, Chetan (författare)
- Norfolk and Norwich University Hospital NHS Trust
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- Ponte, Cristina (författare)
- University of Lisbon,Instituto de Medicina Molecular, Lisboa
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- Salvarani, Carlo (författare)
- Arcispedale Santa Maria Nuova
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- Sivakumar, Rajappa (författare)
- GLB Hospitals and Acute Stroke Centers
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- Tian, Xinping (författare)
- Peking Union Medical College
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- Tomasson, Gunnar (författare)
- University of Iceland
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- Turesson, Carl (författare)
- Lund University,Lunds universitet,Skåne University Hospital
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- Schmidt, Wofgang (författare)
- Immanuel Hospital Berlin
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- Villiger, Peter M. (författare)
- Bern University Hospital
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- Watts, Richard (författare)
- University of East Anglia
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- Young, Chris (författare)
- No affiliation available (private)
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- Luqmani, Raashid Ahmed (författare)
- University of Oxford
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(creator_code:org_t)
- 2019-07-03
- 2020
- Engelska.
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Ingår i: Annals of the Rheumatic Diseases. - : BMJ. - 0003-4967 .- 1468-2060. ; 79:1, s. 19-30
- Relaterad länk:
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http://dx.doi.org/10...
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https://ard.bmj.com/...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background: Since the publication of the European League Against Rheumatism (EULAR) recommendations for the management of large vessel vasculitis (LVV) in 2009, several relevant randomised clinical trials and cohort analyses have been published, which have the potential to change clinical care and therefore supporting the need to update the original recommendations. Methods: Using EULAR standardised operating procedures for EULAR-endorsed recommendations, the EULAR task force undertook a systematic literature review and sought opinion from 20 experts from 13 countries. We modified existing recommendations and created new recommendations. Results: Three overarching principles and 10 recommendations were formulated. We recommend that a suspected diagnosis of LVV should be confirmed by imaging or histology. High dose glucocorticoid therapy (40-60 mg/day prednisone-equivalent) should be initiated immediately for induction of remission in active giant cell arteritis (GCA) or Takayasu arteritis (TAK). We recommend adjunctive therapy in selected patients with GCA (refractory or relapsing disease, presence of an increased risk for glucocorticoid-related adverse events or complications) using tocilizumab. Methotrexate may be used as an alternative. Non-biological glucocorticoid-sparing agents should be given in combination with glucocorticoids in all patients with TAK and biological agents may be used in refractory or relapsing patients. We no longer recommend the routine use of antiplatelet or anticoagulant therapy for treatment of LVV unless it is indicated for other reasons. Conclusions: We have updated the recommendations for the management of LVV to facilitate the translation of current scientific evidence and expert opinion into better management and improved outcome of patients in clinical practice.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
Nyckelord
- Eular recommendations
- giant cell arteritis
- large vessel vasculitis
- management
- Takayasu arteritis
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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- Av författaren/redakt...
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Hellmich, Bernha ...
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Agueda, Ana
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Monti, Sara
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Buttgereit, Fran ...
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De Boysson, Hube ...
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Brouwer, Elisabe ...
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Cassie, Rebecca
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Cid, Maria Cinta
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Dasgupta, Bhaska ...
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Dejaco, Christia ...
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Hatemi, Gulen
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Hollinger, Nicol ...
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Mahr, Alfred
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Mollan, Susan P.
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Mukhtyar, Chetan
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Ponte, Cristina
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Salvarani, Carlo
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Sivakumar, Rajap ...
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Tian, Xinping
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Tomasson, Gunnar
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Turesson, Carl
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Schmidt, Wofgang
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Villiger, Peter ...
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Watts, Richard
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Young, Chris
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Luqmani, Raashid ...
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