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Factors associated ...
Factors associated with diagnostic discrepancy for left ventricular hypertrophy between electrocardiography and echocardiography
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- Petersen, Søren Sandager (author)
- Odense University Hospital
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- Pedersen, Line Reinholdt (author)
- Odense University Hospital
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- Pareek, Manan (author)
- Odense University Hospital
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- Nielsen, Mette Lundgren (author)
- Odense University Hospital
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- Diederichsen, Søren Zöga (author)
- Odense University Hospital
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- Leósdóttir, Margrét (author)
- Skåne University Hospital
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- Nilsson, Peter M. (author)
- Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups
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- Diederichsen, Axel Cosmus Pyndt (author)
- Odense University Hospital
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- Olsen, Michael Hecht (author)
- Odense University Hospital
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(creator_code:org_t)
- 2016-09-23
- 2017
- English.
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In: Blood Pressure. - : Informa UK Limited. - 0803-7051 .- 1651-1999. ; 26:1, s. 54-63
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Abstract
Subject headings
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- Objective: To investigate the influence of cardiovascular risk factors, including fasting plasma glucose (FPG), on the association between electrocardiographic (ECG) and echocardiographic left ventricular hypertrophy (LVH) in an elderly population. Methods: We tested cross-sectional associations between electrocardiographic and echocardiographic LVH, defining LVH according to the Sokolow-Lyon voltage combination, Cornell voltage-duration product, or left ventricular mass index (LVMI). Differences between standardized LVMI and Sokolow-Lyon voltage combination or Cornell voltage-duration product (absolute value/cut-off value for LVH) were used as outcome variables in order to identify explanatory variables associated with diagnostic discrepancies between ECG and echocardiography. Results: Of the 1382 subjects included, 77% did not display any signs of LVH, 6% had LVH defined by ECG only, 13% had LVH defined by echocardiography only, and 5% had LVH on both ECG and echocardiography. Older subjects and those with higher blood pressure and RWT were more likely to have a relatively greater LVMI on echocardiography than that predicted on ECG (odds ratio: 1.65 per 10 years (95% confidence interval (CI): 1.27-2.15), p = .0002, odds ratio: 1.17 per 10 mmHg (95% CI: 1.09-1.25), p < .0001, and odds ratio: 1.21 per 0.10 (95% CI: 1.02-1.42), p = .03). In addition, discrepancy was also seen in females and subjects receiving antihypertensive medication (odds ratio: 1.41 (95% CI: 1.04-1.89), p = .03 and odds ratio: 1.41 (95% CI: 1.06-1.87), p = .02), but FPG did not independently influence discrepancy between ECG and echocardiography. Conclusion: Age, blood pressure, female sex, greater RWT and use of antihypertensive medication were associated with a greater risk of non-consistency between LVH determined by ECG and echocardiography.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- Discrepancy
- ECG
- echocardiography
- left ventricular hypertrophy
- left ventricular mass
Publication and Content Type
- art (subject category)
- ref (subject category)
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