SwePub
Sök i LIBRIS databas

  Extended search

WFRF:(Day Andrew)
 

Search: WFRF:(Day Andrew) > The evaluation of t...

  • Ferrari, Pietro (author)

The evaluation of the diet/disease relation in the EPIC study: considerations for the calibration and the disease models

  • Article/chapterEnglish2008

Publisher, publication year, extent ...

  • 2008-01-07
  • Oxford University Press (OUP),2008

Numbers

  • LIBRIS-ID:oai:lup.lub.lu.se:dea6c312-32df-41d4-bf26-d186c2a018fb
  • https://lup.lub.lu.se/record/1207471URI
  • https://doi.org/10.1093/ije/dym242DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:art swepub-publicationtype
  • Subject category:ref swepub-contenttype

Notes

  • Background International multicentre studies on diet and cancer are relatively new in epidemiological research. They offer a series of challenging methodological issues for the evaluation of the association between dietary exposure and disease outcomes, which can both be quite heterogeneous across different geographical regions. This requires considerable work to standardize dietary measurements at the food and the nutrient levels. Methods Within the European Prospective Investigation into Cancer and Nutrition (EPIC), a calibration study was set up to express individual dietary intakes according to the same reference scale. A linear regression calibration model was used to correct the association between diet and disease for measurement errors in dietary exposures. In the present work, we describe an approach for analysing the EPIC data, using as an example the evaluation of the association between fish intake and colorectal cancer incidence. Results Sex- and country-specific attenuation factors ranged from 0.083 to 0.784, with values overall higher for men compared with women. Hazard ratio estimates of colorectal cancer for a 10 g/day increase in fish intake were 0.97 [95 confidence interval (CI): 0.950.99] and 0.93 (0.880.98), before and after calibration, respectively. Conclusions In a multicentre study, the diet/disease association can be evaluated by exploiting the whole variability of intake over the entire study. Calibration may reduce between-centre heterogeneity in the dietdisease relationship caused by differential impact of measurement errors across cohorts.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Day, Nicholas E. (author)
  • Boshuizen, Hendriek C. (author)
  • Roddam, Andrew (author)
  • Hoffmann, Kurt (author)
  • Thiebaut, Anne (author)
  • Pera, Guillem (author)
  • Overvad, Kim (author)
  • Lund, Eiliv (author)
  • Trichopoulou, Antonia (author)
  • Tumino, Rosario (author)
  • Gullberg, BoLund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups(Swepub:lu)smi-bgu (author)
  • Norat, Teresa (author)
  • Slimani, Nadia (author)
  • Kaaks, Rudolf (author)
  • Riboli, Elio (author)
  • NutritionsepidemiologiForskargrupper vid Lunds universitet (creator_code:org_t)

Related titles

  • In:International Journal of Epidemiology: Oxford University Press (OUP)37:2, s. 368-3781464-36850300-5771

Internet link

Find in a library

To the university's database

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view