Assessing Healthy Aging Score and Its Association With All-Cause Mortality: Findings From the China Health and Retirement Longitudinal Study

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Zeng, Zihang (författare)

Assessing Healthy Aging Score and Its Association With All-Cause Mortality : Findings From the China Health and Retirement Longitudinal Study

Artikel/kapitelEngelska2023

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2023-01-30
Oxford University Press (OUP),2023
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LIBRIS-ID:oai:DiVA.org:su-216800
https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-216800URI
https://doi.org/10.1093/geroni/igad006DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:152326795URI

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Språk:engelska
Sammanfattning på:engelska

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Background and Objectives: To construct a comprehensive healthy aging score (HAS) and explore its association with all-cause mortality and its potential interactions with other demographics on mortality.Research Design and Methods: This study included 5,409 participants aged ≥60 years from the China Health and Retirement Longitudinal Study. An HAS was constructed based on three dimensions of healthy aging including intrinsic capacity (IC), environmental support (ES), and chronic disease (CD), which were assessed at baseline, and categorized by tertiles (poor, moderate, and high). Participants were followed up biennially for all-cause mortality through the death registration or family interview from 2011 to 2018. Data were analyzed using Cox regression, Laplace regression, and receiver-operating characteristic analysis.Results: During 7 years of follow-up, 877 (16.21%) participants died. An HAS was constructed based on the cognition, mobility, and instrumental activity of daily living in the IC dimension; housing in the ES dimension; and hypertension, diabetes, chronic lung disease, stroke, and cancer in the CD dimension, which was associated with death. HAS seems a good predictor of all-cause mortality, with an area under the curve of 0.749. The hazard ratios and 95% confidence intervals for all-cause mortality related to moderate and poor HAS (vs high HAS) were 1.26 (1.01–1.56) and 2.38 (1.94–2.91), respectively. The median survival time was 2.46 years shorter in participants with poor HAS than those with high HAS. There were significant additive interactions of HAS with age, sex, and marital status on death.Discussion and Implications: Poor HAS may increase mortality and shorten survival, especially among older, male, and single adults.

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Annan medicin och hälsovetenskap Gerontologi, medicinsk/hälsovetenskaplig inriktning hsv//swe
MEDICAL AND HEALTH SCIENCES Other Medical and Health Sciences Gerontology, specialising in Medical and Health Sciences hsv//eng
Chronic diseases
Cohort study
Environmental support
Healthy aging
Intrinsic capacity

Biuppslag (personer, institutioner, konferenser, titlar ...)

Li, Xuerui (författare)
Yang, Wenzhe (författare)
Wang, Jiao (författare)
Zhu, Yun (författare)
Qi, Xiuying (författare)
Xu, WeiliKarolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Tianjin Medical University, China (författare)
Stockholms universitetCentrum för forskning om äldre och åldrande (ARC), (tills m KI) (creator_code:org_t)

Sammanhörande titlar

Ingår i:Innovation in Aging: Oxford University Press (OUP)7:22399-5300

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Av författaren/redakt...: Zeng, Zihang; Li, Xuerui; Yang, Wenzhe; Wang, Jiao; Zhu, Yun; Qi, Xiuying; visa fler...; Xu, Weili; visa färre...

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Annan medicin oc ...; och Gerontologi medi ...

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Av lärosätet: Stockholms universitet; Karolinska Institutet

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