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Emerging role of ne...
Emerging role of neuregulin as a modulator of muscle metabolism
- Article/chapterEnglish2010
Publisher, publication year, extent ...
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American Physiological Society,2010
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LIBRIS-ID:oai:prod.swepub.kib.ki.se:120167341
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http://kipublications.ki.se/Default.aspx?queryparsed=id:120167341URI
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https://doi.org/10.1152/ajpendo.00541.2009DOI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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restricted
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Neuregulin was described initially as a neurotrophic factor involved in the formation of the neuromuscular junction in skeletal muscle. However, in recent years, neuregulin has been reported to be a myokine that exerts relevant effects on myogenesis and the regulation of muscle metabolism. In this new context, the rapid and chronic metabolic effects of neuregulin appear to be related to muscle contraction. Indeed, the effects of neuregulin resemble those of exercise, which are accompanied by an improvement in insulin sensitivity. In this review, we challenge the classical role assigned to neuregulin in muscle and propound the emerging concept of its involvement in the regulation of energetic metabolism and insulin responsiveness.
Added entries (persons, corporate bodies, meetings, titles ...)
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Martinez-Redondo, VKarolinska Institutet
(author)
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Lopez-Soldado, I
(author)
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Canto, C
(author)
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Zorzano, A
(author)
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Karolinska Institutet
(creator_code:org_t)
Related titles
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In:American journal of physiology. Endocrinology and metabolism: American Physiological Society298:4, s. E742-E7501522-15550193-1849
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