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ECIL guidelines for...
ECIL guidelines for preventing Pneumocystis jirovecii pneumonia in patients with haematological malignancies and stem cell transplant recipients
- Article/chapterEnglish2016
Publisher, publication year, extent ...
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2016-05-12
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Oxford University Press (OUP),2016
Numbers
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LIBRIS-ID:oai:prod.swepub.kib.ki.se:134287363
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http://kipublications.ki.se/Default.aspx?queryparsed=id:134287363URI
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https://doi.org/10.1093/jac/dkw157DOI
Supplementary language notes
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Language:English
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Summary in:English
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Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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The 5th European Conference on Infections in Leukaemia (ECIL-5) meeting aimed to establish evidence-based recommendations for the prophylaxis of Pneumocystis jirovecii pneumonia (PCP) in non-HIV-infected patients with an underlying haematological condition, including allogeneic HSCT recipients. Recommendations were based on the grading system of the IDSA. Trimethoprim/sulfamethoxazole given 2–3 times weekly is the drug of choice for the primary prophylaxis of PCP in adults (A-II) and children (A-I) and should be given during the entire period at risk. Recent data indicate that children may benefit equally from a once-weekly regimen (B-II). All other drugs, including pentamidine, atovaquone and dapsone, are considered second-line alternatives when trimethoprim/sulfamethoxazole is poorly tolerated or contraindicated. The main indications of PCP prophylaxis are ALL, allogeneic HSCT, treatment with alemtuzumab, fludarabine/cyclophosphamide/rituximab combinations, >4 weeks of treatment with corticosteroids and well-defined primary immune deficiencies in children. Additional indications are proposed depending on the treatment regimen.
Added entries (persons, corporate bodies, meetings, titles ...)
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Cesaro, S
(author)
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Maschmeyer, G
(author)
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Einsele, H
(author)
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Donnelly, JP
(author)
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Alanio, A
(author)
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Hauser, PM
(author)
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Lagrou, K
(author)
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Melchers, WJG
(author)
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Helweg-Larsen, J
(author)
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Matos, O
(author)
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Bretagne, S
(author)
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Cordonnier, C
(author)
Related titles
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In:The Journal of antimicrobial chemotherapy: Oxford University Press (OUP)71:9, s. 2397-24041460-20910305-7453
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Maertens, J
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Cesaro, S
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Maschmeyer, G
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Einsele, H
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Donnelly, JP
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Alanio, A
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show more...
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Hauser, PM
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Lagrou, K
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Melchers, WJG
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Helweg-Larsen, J
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Matos, O
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Bretagne, S
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Cordonnier, C
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- Articles in the publication
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The Journal of a ...
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Karolinska Institutet