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A single-cell hematopoietic landscape resolves 8 lineage trajectories and defects in Kit mutant mice
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- Dahlin, JS (author)
- Karolinska Institutet
- Hamey, FK (author)
- Pijuan-Sala, B (author)
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- Shepherd, M (author)
- Lau, WWY (author)
- Nestorowa, S (author)
- Weinreb, C (author)
- Wolock, S (author)
- Hannah, R (author)
- Diamanti, E (author)
- Kent, DG (author)
- Gottgens, B (author)
- Wilson, NK (author)
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- (creator_code:org_t)
- American Society of Hematology, 2018
- 2018
- English.
- In: Blood. - : American Society of Hematology. - 1528-0020 .- 0006-4971. ; 131:21, s. E1-E11
- Journal article (peer-reviewed)
Abstract
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- Single-cell transcriptional landscape of 44 802 hematopoietic stem/progenitor cells defines entry points to 8 different blood lineages. Comparison with 13 815 c-Kit mutant cells identifies pleiotropic changes in cell type abundance and underlying molecular profiles.
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- Dahlin, JS
- Hamey, FK
- Pijuan-Sala, B
- Shepherd, M
- Lau, WWY
- Nestorowa, S
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- Weinreb, C
- Wolock, S
- Hannah, R
- Diamanti, E
- Kent, DG
- Gottgens, B
- Wilson, NK
- show less...
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- Blood
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- Karolinska Institutet
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