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COVID-19 in Patient...
COVID-19 in Patients with Glomerular Disease: Follow-Up Results from the IRoc-GN International Registry
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- Waldman, Meryl (författare)
- NIDDK, MD 20892 USA
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- Soler, Maria Jose (författare)
- Hosp Univ Vall dHebron, Spain; Vall dHebron Hosp Univ, Spain
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- Garcia-Carro, Clara (författare)
- Hosp Univ Vall dHebron, Spain; Vall dHebron Hosp Univ, Spain
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- Lightstone, Liz (författare)
- Imperial Coll London, England; Imperial Coll Healthcare NHS Trust Renal & Transp, England,Icahn Sch Med Mt Sinai, NY 10029 USA
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- Turner-Stokes, Tabitha (författare)
- Imperial Coll London, England; Imperial Coll Healthcare NHS Trust Renal & Transp, England
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- Griffith, Megan (författare)
- Imperial Coll Healthcare NHS Trust Renal & Transp, England
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- Torras, Joan (författare)
- Barcelona Univ, Spain
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- Martinez Valenzuela, Laura (författare)
- Barcelona Univ, Spain
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- Bestard, Oriol (författare)
- Hosp Univ Vall dHebron, Spain; Vall dHebron Hosp Univ, Spain
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- Geddes, Colin (författare)
- Queen Elizabeth Univ Hosp, Scotland
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- Flossmann, Oliver (författare)
- Royal Berkshire Hosp, England
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- Budge, Kelly L. (författare)
- Icahn Sch Med Mt Sinai, NY 10029 USA
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- Cantarelli, Chiara (författare)
- Univ Parma, Italy
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- Fiaccadori, Enrico (författare)
- Univ Parma, Italy
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- Delsante, Marco (författare)
- Univ Parma, Italy
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- Morales, Enrique (författare)
- Hosp Univ 12 Octubre, Spain
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- Gutierrez, Eduardo (författare)
- Hosp Univ 12 Octubre, Spain
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- Nino-Cruz, Jose A. (författare)
- Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Mexico,Inst Salud Carlos III, Spain; Univ Autonoma Madrid, Spain
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- Martinez-Rueda, Armando J. (författare)
- Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Mexico
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- Comai, Giorgia (författare)
- Alma Mater Studiorum Univ Bologna, Italy
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- Bini, Claudia (författare)
- Alma Mater Studiorum Univ Bologna, Italy
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- La Manna, Gaetano (författare)
- Alma Mater Studiorum Univ Bologna, Italy
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- Slon, Maria F. (författare)
- Hosp Univ Navarra, Spain
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- Manrique, Joaquin (författare)
- Hosp Univ Navarra, Spain
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- Avello, Alejandro (författare)
- Karolinska Institutet
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- Fernandez-Prado, Raul (författare)
- Inst Salud Carlos III, Spain; Univ Autonoma Madrid, Spain
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- Ortiz, Alberto (författare)
- Inst Salud Carlos III, Spain; Univ Autonoma Madrid, Spain
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- Marinaki, Smaragdi (författare)
- Laikon Gen Hosp, Greece
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- Martin Varas, Carmen Rita (författare)
- Hosp Gen Segovia, Spain
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- Rabasco Ruiz, Cristina (författare)
- Hosp Univ Reina Sofia, Spain
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- Sierra-Carpio, Milagros (författare)
- Hosp San Pedro, Spain
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- Garcia-Agudo, Rebeca (författare)
- La Mancha Ctr Hosp, Spain
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- Juarez, Gema Fernandez (författare)
- Hosp Univ Fdn Alcorcon, Spain
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- Hamilton, Alexander J. (författare)
- Royal Devon & Exeter NHS Fdn Trust, England
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- Bruchfeld, Annette (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Njurmedicinska kliniken US,Karolinska Inst, Sweden
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- Chrysochou, Constantina (författare)
- Univ Manchester, England; Salford Royal NHS Fdn Trust, England
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- Howard, Lilian (författare)
- NIDDK, MD 20892 USA
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- Sinha, Smeeta (författare)
- Univ Manchester, England; Salford Royal NHS Fdn Trust, England
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- Leach, Tim (författare)
- Portsmouth Hosp NHS Trust, England
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- Pamplona, Irene Agraz (författare)
- Hosp Univ Vall dHebron, Spain; Vall dHebron Hosp Univ, Spain
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- Maggiore, Umberto (författare)
- Univ Parma, Italy
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- Cravedi, Paolo (författare)
- Icahn Sch Med Mt Sinai, NY 10029 USA
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(creator_code:org_t)
- AMER SOC NEPHROLOGY, 2022
- 2022
- Engelska.
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Ingår i: KIDNEY360. - : AMER SOC NEPHROLOGY. - 2641-7650. ; 3:2, s. 293-306
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.3...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background The acute and long-term effects of severe acute respiratory syndrome coronavirus 2 infection in individuals with GN are still unclear. To address this relevant issue, we created the International Registry of COVID-19 infection in GN.Methods We collected serial information on kidney-related and-unrelated outcomes from 125 GN patients (63 hospitalized and 62 outpatients) and 83 non-GN hospitalized patients with coronavirus disease 2019 (COVID-19) and a median follow-up period of 6.4 (interquartile range 2.3-9.6) months after diagnosis. We used logistic regression for the analyses of clinical outcomes and linear mixed models for the longitudinal analyses of eGFR. All multiple regression models were adjusted for age, sex, ethnicity, and renin-angiotensin-aldosterone system inhibitor use.Results After adjustment for pre-COVID-19 eGFR and other confounders, mortality and AKI did not differ between GN patients and controls (adjusted odds ratio for AKI=1.28; 95% confidence interval [CI], 0.46 to 3.60; P=0.64). The main predictor of AKI was pre-COVID-19 eGFR (adjusted odds ratio per 1 SD unit decrease in eGFR=3.04; 95% CI, 1.76 to 5.28; P,0.001). GN patients developing AKI were less likely to recover pre-COVID19 eGFR compared with controls (adjusted 6-month post-COVID-19 eGFR=0.41; 95% CI, 0.25 to 0.56; times preCOVID-19 eGFR). Shorter duration of GN diagnosis, higher pre-COVID-19 proteinuria, and diagnosis of focal segmental glomerulosclerosis or minimal change disease were associated with a lower post-COVID-19 eGFR.Conclusions Pre-COVID-19 eGFR is the main risk factor for AKI regardless of GN diagnosis. However, GN patients are at higher risk of impaired eGFR recovery after COVID-19-associated AKI. These patients (especially those with high baseline proteinuria or a diagnosis of focal segmental glomerulosclerosis or minimal change disease) should be closely monitored not only during the acute phases of COVID-19 but also after its resolution.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- glomerular and tubulointerstitial diseases; COVID-19; follow-up studies; glomerular disease; kidney glomerulus; registries
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Waldman, Meryl
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Soler, Maria Jos ...
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Garcia-Carro, Cl ...
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Lightstone, Liz
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Turner-Stokes, T ...
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Griffith, Megan
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visa fler...
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Torras, Joan
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Martinez Valenzu ...
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Bestard, Oriol
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Geddes, Colin
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Flossmann, Olive ...
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Budge, Kelly L.
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Cantarelli, Chia ...
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Fiaccadori, Enri ...
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Delsante, Marco
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Morales, Enrique
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Gutierrez, Eduar ...
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Nino-Cruz, Jose ...
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Martinez-Rueda, ...
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Comai, Giorgia
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Bini, Claudia
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La Manna, Gaetan ...
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Slon, Maria F.
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Manrique, Joaqui ...
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Avello, Alejandr ...
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Fernandez-Prado, ...
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Ortiz, Alberto
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Marinaki, Smarag ...
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Martin Varas, Ca ...
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Rabasco Ruiz, Cr ...
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Sierra-Carpio, M ...
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Garcia-Agudo, Re ...
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Juarez, Gema Fer ...
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Hamilton, Alexan ...
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Bruchfeld, Annet ...
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Chrysochou, Cons ...
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Howard, Lilian
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Sinha, Smeeta
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Leach, Tim
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Pamplona, Irene ...
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Maggiore, Umbert ...
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Cravedi, Paolo
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
- Artiklar i publikationen
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KIDNEY360
- Av lärosätet
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Linköpings universitet
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Karolinska Institutet