Sökning: L773:1058 4838 OR L773:1537 6591
> (2015-2019) >
Definitions of Resi...
Definitions of Resistant and Refractory Cytomegalovirus Infection and Disease in Transplant Recipients for Use in Clinical Trials
-
Chemaly, RF (författare)
-
Chou, S (författare)
-
Einsele, H (författare)
-
visa fler...
-
Griffiths, P (författare)
-
Avery, R (författare)
-
Razonable, RR (författare)
-
Mullane, KM (författare)
-
Kotton, C (författare)
-
Lundgren, J (författare)
-
Komatsu, TE (författare)
-
Lischka, P (författare)
-
Josephson, F (författare)
-
Douglas, CM (författare)
-
Umeh, O (författare)
-
Miller, V (författare)
-
- Ljungman, P (författare)
- Karolinska Institutet
-
visa färre...
-
(creator_code:org_t)
- 2018-08-22
- 2019
- Engelska.
-
Ingår i: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. - : Oxford University Press (OUP). - 1537-6591. ; 68:8, s. 1420-1426
- Relaterad länk:
-
https://europepmc.or...
-
visa fler...
-
http://kipublication...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Despite advances in preventive strategies, cytomegalovirus (CMV) infection remains a major complication in solid organ and hematopoietic cell transplant recipients. CMV infection may fail to respond to commercially available antiviral therapies, with or without demonstrating genotypic mutation(s) known to be associated with resistance to these therapies. This lack of response has been termed “resistant/refractory CMV” and is a key focus of clinical trials of some investigational antiviral agents. To provide consistent criteria for future clinical trials and outcomes research, the CMV Resistance Working Group of the CMV Drug Development Forum (consisting of scientists, clinicians, regulatory officials, and industry representatives from the United States, Canada, and Europe) has undertaken establishing standardized consensus definitions of “resistant” and “refractory” CMV. These definitions have emerged from the Working Group’s review of the available virologic and clinical literature and will be subject to reassessment and modification based on results of future studies.
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Chemaly, RF
-
Chou, S
-
Einsele, H
-
Griffiths, P
-
Avery, R
-
Razonable, RR
-
visa fler...
-
Mullane, KM
-
Kotton, C
-
Lundgren, J
-
Komatsu, TE
-
Lischka, P
-
Josephson, F
-
Douglas, CM
-
Umeh, O
-
Miller, V
-
Ljungman, P
-
visa färre...
- Artiklar i publikationen
-
Clinical infecti ...
-
Clinical Infecti ...
- Av lärosätet
-
Karolinska Institutet