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  • Courtois, A (author)

Positron Emission Tomography/Computed Tomography Predicts and Detects Complications After Endovascular Repair of Abdominal Aortic Aneurysms

  • Article/chapterEnglish2019

Publisher, publication year, extent ...

  • 2019-05-10
  • SAGE Publications,2019

Numbers

  • LIBRIS-ID:oai:prod.swepub.kib.ki.se:141398937
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:141398937URI
  • https://doi.org/10.1177/1526602819849088DOI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Purpose: To assess if aortic 18F-fluorodeoxyglucose (FDG) uptake on positron emission tomography/computed tomography (PET/CT) could play a role in predicting complications after endovascular aneurysm repair (EVAR). Materials and Methods: This study involved 2 cohorts of men with abdominal aortic aneurysm treated by EVAR: those who underwent a PET/CT scan before EVAR (n=17) and those who had a PET/CT during follow-up (n=34). Uptake of FDG was measured as the standardized uptake value (SUV). D-dimer, a marker of fibrinolysis, was measured in blood drawn concomitantly with the PET/CT. Results: A significant uptake of FDG in the aneurysm wall was detected by PET/CT before EVAR in 6 of 17 patients. During the first year after EVAR, type II endoleaks developed in 5 of these FDG+ patients vs 3 of 11 FDG– patients (p=0.04). Two of the FDG+ patients had continued sac growth and required conversion to open repair. A significant association between sac growth rate, SUV, and the presence of endoleak was found in the 34 patients who underwent PET/CT after EVAR. Finally, D-dimer was significantly increased in patients with both endoleak and positive PET/CT in the post-EVAR group. Conclusion: This study suggests that the presence of FDG uptake in the aortic wall might be a useful tool to predict patients at high risk of developing post-EVAR complications.

Added entries (persons, corporate bodies, meetings, titles ...)

  • Makrygiannis, G (author)
  • El Hachemi, M (author)
  • Hultgren, RKarolinska Institutet (author)
  • Allaire, E (author)
  • Namur, G (author)
  • Hustinx, R (author)
  • Defraigne, JO (author)
  • Sakalihasan, N (author)
  • Karolinska Institutet (creator_code:org_t)

Related titles

  • In:Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists: SAGE Publications26:4, s. 520-5281545-1550
  • In:Journal of Endovascular Therapy: SAGE Publications26:4, s. 520-5281526-6028

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