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Novel Blood Pressur...
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Wain, Louise V.Univ Leicester, Dept Hlth Sci, Leicester, Leics, England.,Univ Edinburgh, MRC Human Genet Unit, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Western Gen Hosp, MRC Human Genet Unit, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.
(author)
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney
- Article/chapterEnglish2017
Publisher, publication year, extent ...
Numbers
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LIBRIS-ID:oai:DiVA.org:su-147011
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https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-147011URI
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https://doi.org/10.1161/HYPERTENSIONAHA.117.09438DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-334925URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:136525536URI
Supplementary language notes
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Language:English
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Summary in:English
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Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Elevated blood pressure is a major risk factor for cardiovascular disease and has a substantial genetic contribution. Genetic variation influencing blood pressure has the potential to identify new pharmacological targets for the treatment of hypertension. To discover additional novel blood pressure loci, we used 1000 Genomes Project-based imputation in 150 134 European ancestry individuals and sought significant evidence for independent replication in a further 228 245 individuals. We report 6 new signals of association in or near HSPB7, TNXB, LRP12, LOC283335, SEPT9, and AKT2, and provide new replication evidence for a further 2 signals in EBF2 and NFKBIA. Combining large whole-blood gene expression resources totaling 12 607 individuals, we investigated all novel and previously reported signals and identified 48 genes with evidence for involvement in blood pressure regulation that are significant in multiple resources. Three novel kidney-specific signals were also detected. These robustly implicated genes may provide new leads for therapeutic innovation.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Vaez, AhmadUniv Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands.;Isfahan Univ Med Sci, Res Inst Primordial Prevent Noncommunicable Dis, Tehran, Iran.
(author)
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Jansen, RickKarolinska Institutet
(author)
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Joehanes, RobyHarvard Med Sch, Hebrew SeniorLife, Boston, MA USA.;Framingham Heart Dis Epidemiol Study, Natl Heart Lung & Blood Inst, Framingham, MA USA.
(author)
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van der Most, Peter J.Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands.,Imperial Coll London, Natl Heart & Lung Inst, London, England.
(author)
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Erzurumluoglu, A. MesutUniv Leicester, Dept Hlth Sci, Leicester, Leics, England.
(author)
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O'Reilly, Paul F.Kings Coll London, Inst Psychiat Psychol & Neurosci, London, England. Kings Coll London, Dept Twin Res & Genet Epidemiol, London, England.
(author)
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Cabrera, Claudia P.William Harvey Res Inst, Clin Pharmacol, London, England.;Queen Mary Univ London, NIHR Barts Cardiovasc Biomed Res Unit, Barts & London Sch Med & Dent, London, England.
(author)
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Warren, Helen R.William Harvey Res Inst, Clin Pharmacol, London, England.;Queen Mary Univ London, NIHR Barts Cardiovasc Biomed Res Unit, Barts & London Sch Med & Dent, London, England.,Univ Med Greifswald, Inst Physiol, Karlsburg, Germany.
(author)
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Rose, Lynda M.Brigham & Womens Hosp, Div Prevent Med, 75 Francis St, Boston, MA 02115 USA.,Natl Inst Hlth Res, Biomed Res Ctr, London, England.
(author)
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Verwoert, Germaine C.Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands.
(author)
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Hottenga, Jouke-JanVrije Univ, VU Univ Med Ctr, EMGO Inst, Dept Biol Psychol, Amsterdam, Netherlands.,Vrije Univ Amsterdam Med Ctr, EMGO Inst Hlth & Care Res, Dept Psychiat, Amsterdam, Netherlands.
(author)
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Strawbridge, Rona J.Karolinska Inst, Dept Med Solna, Cardiovasc Med Unit, Stockholm, Sweden.;Karolinska Univ, Ctr Mol Med, Solna, Sweden.
(author)
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Esko, TonuChildrens Hosp, Div Endocrinol, Boston, MA USA.;Broad Inst Harvard & MIT, Cambridge, MA USA.
(author)
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Arking, Dan E.Johns Hopkins Univ, McKusick Nathans Inst Genet Med, Ctr Complex Dis Genom, Sch Med, Baltimore, MD USA.,Imperial Coll London, Dept Epidemiol & Biostat, Sch Publ Hlth, London, England.;Univ Ioannina, Dept Hyg & Epidemiol, Sch Med, Ioannina, Greece.
(author)
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Hwang, Shih-JenNHLBI, Populat Sci Branch, Div Intramural Res, Bldg 10, Bethesda, MD 20892 USA.;Framingham Heart Dis Epidemiol Study, Framingham, MA USA.
(author)
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Guo, XiuqingHarbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Dept Pediat, Torrance, CA USA.
(author)
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Kutalik, ZoltanUniv Lausanne Hosp, Inst Social & Prevent Med, Lausanne, Switzerland.;Swiss Inst Bioinformat, Lausanne, Switzerland.
(author)
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Trompet, StellaLeiden Univ, Med Ctr, Dept Cardiol, Leiden, Netherlands.;Leiden Univ, Med Ctr, Dept Gerontol & Geriatr, Leiden, Netherlands.;Leiden Univ, Med Ctr, Dept Clin Epidemiol, Leiden, Netherlands.
(author)
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Shrine, NickUniv Leicester, Dept Hlth Sci, Leicester, Leics, England.
(author)
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Teumer, AlexanderUniv Med Greifswald, Inst Community Med, Greifswald, Germany.;DZHK German Ctr Cardiovasc Res, Greifswald, Germany.
(author)
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Ried, Janina S.Helmholtz Zentrum Munchen, Inst Epidemiol 2, Munich, Germany.,Univ Tartu, Inst Biomed & Translat Med, Tartu, Estonia.
(author)
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Bis, Joshua C.Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA USA.
(author)
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Smith, Albert V.Icelandic Heart Assoc, Kopavogur, Iceland.;Univ Iceland, Fac Med, Reykjavik, Iceland.
(author)
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Amin, NajafErasmus MC, Genet Epidemiol Unit, Dept Epidemiol, Rotterdam, Netherlands.,Univ Dundee, Med Res Inst, Ninewells Hosp, Dundee, Scotland.;Univ Dundee, Sch Med, Dundee, Scotland.
(author)
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Nolte, Ilja M.Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands.
(author)
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Lyytikainen, Leo-PekkaFimlab Labs, Dept Clin Chem, Tampere, Finland.;Univ Tampere, Fac Med & Life Sci, Dept Clin Chem, Tampere, Finland.
(author)
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Mahajan, AnubhaUniv Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.
(author)
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Wareham, Nicholas J.Univ Cambridge, MRC Epidemiol Unit, Sch Clin Med, Inst Metab Sci, Cambridge, England.
(author)
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Hofer, EdithMed Univ Graz, Clin Div Neurogeriatr, Dept Neurol, Graz, Austria.;Med Univ Graz, Inst Med Informat Stat & Documentat, Graz, Austria.
(author)
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Joshi, Peter K.Univ Edinburgh, Ctr Global Hlth Res, Usher Inst Populat Hlth Sci & Informat, Edinburgh, Midlothian, Scotland.,Dept Hlth, Helsinki, Finland. Chron Dis Prevent Unit, Helsinki, Finland. Natl Inst Hlth & Welf, Helsinki, Finland.
(author)
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Kristiansson, Kati
(author)
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Traglia, MichelaIst Sci San Raffaele, Div Genet & Cell Biol, Milan, Italy.
(author)
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Havulinna, Aki S.Dept Hlth, Helsinki, Finland. Chron Dis Prevent Unit, Helsinki, Finland. Natl Inst Hlth & Welf, Helsinki, Finland.
(author)
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Goel, AnujUniv Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Div Cardiovasc Med, Radcliffe Dept Med, Oxford, England.
(author)
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Nalls, Mike A.NIA, Neurogenet Lab, Bethesda, MD 20892 USA.;Data Tecn Int, Glen Echo, MD USA.
(author)
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Sober, SiimUniv Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Univ Leicester, NIHR Leicester Biomed Res Ctr, Leicester, Leics, England.;Glenfield Hosp, NIHR Leicester Cardiovasc Biomed Res Unit, Leicester, Leics, England.;Univ Edinburgh, Western Gen Hosp, MRC Human Genet Unit, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.,Univ Dundee, Med Res Inst, Ninewells Hosp, Dundee, Scotland.;Univ Dundee, Sch Med, Dundee, Scotland.,London North West Healthcare NHS Trust, Ealing Hosp, Dept Cardiol, Southall, Middx, England.;Imperial Coll Healthcare NHS Trust, London, England.;Imperial Coll London, Natl Heart & Lung Inst, Hammersmith Hosp Campus, London, England.
(author)
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Vuckovic, DraganaIRCCS Burlo Garofolo Children Hosp, Med Genet, Trieste, Italy.;Univ Trieste, Dept Med Surg & Hlth Sci, Trieste, Italy.
(author)
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Luan, Jian'anUniv Cambridge, MRC Epidemiol Unit, Sch Clin Med, Inst Metab Sci, Cambridge, England.
(author)
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Del Greco M, FabiolaUniv Lubeck, Inst Biomed, Affiliated Inst, Eurac Res, Bolzano, Italy.
(author)
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Lind, LarsUppsala universitet,Kardiovaskulär epidemiologi(Swepub:uu)larslind
(author)
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Marrugat, JaumeIMIM, Cardiovasc Epidemiol & Genet, Barcelona, Spain.;CIBERCV, Barcelona, Spain.
(author)
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Ruggiero, DanielaCNR, Inst Genet & Biophys A Buzzati Traverso, Naples, Italy.
(author)
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Lopez, Lorna M.Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland.;Beaumont Hosp, Dept Psychiat, Royal Coll Surg Ireland, Educ & Res Ctr, Dublin, Ireland.;Univ Coll Dublin, UCD Conway Inst, Ctr Proteome Res, Belfield, Ireland.;Univ Coll Dublin, Sch Med, Conway Inst, Belfield, Ireland.
(author)
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Niiranen, TeemuDept Hlth, Helsinki, Finland. Chron Dis Prevent Unit, Helsinki, Finland. Natl Inst Hlth & Welf, Helsinki, Finland.
(author)
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Enroth, Stefan,1976-Uppsala universitet,Medicinsk genetik och genomik,Science for Life Laboratory, SciLifeLab(Swepub:uu)stenr451
(author)
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Jackson, Anne U.Univ Michigan, Dept Biostat, Ann Arbor, MI USA.;Univ Michigan, Ctr Stat Genet, Ann Arbor, MI USA.
(author)
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Nelson, Christopher P.Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Univ Leicester, NIHR Leicester Biomed Res Ctr, Leicester, Leics, England.;Glenfield Hosp, NIHR Leicester Cardiovasc Biomed Res Unit, Leicester, Leics, England.;Univ Edinburgh, Western Gen Hosp, MRC Human Genet Unit, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.
(author)
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Huffman, Jennifer E.Univ Edinburgh, MRC Human Genet Unit, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Western Gen Hosp, MRC Human Genet Unit, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.
(author)
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Zhang, WeihuaImperial Coll London, Dept Epidemiol & Biostat, Sch Publ Hlth, London, England.;London North West Healthcare NHS Trust, Ealing Hosp, Dept Cardiol, Southall, Middx, England.
(author)
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Marten, JonathanUniv Edinburgh, MRC Human Genet Unit, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Western Gen Hosp, MRC Human Genet Unit, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.
(author)
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Gandin, IlariaUniv Trieste, Dept Med Surg & Hlth Sci, Trieste, Italy.
(author)
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Harris, Sarah E.Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Western Gen Hosp, MRC Human Genet Unit, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Western Gen Hosp, Med Genet Sect, Ctr Genom & Expt Med, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.
(author)
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Zemunik, TatijanaLondon North West Healthcare NHS Trust, Dept Med Biol, Fac Med, Southall, Middx, England.
(author)
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Lu, YingchangIcahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY USA.
(author)
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Evangelou, Evangelos
(author)
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Shah, NabiUniv Dundee, Med Res Inst, Ninewells Hosp, Dundee, Scotland.;Univ Dundee, Sch Med, Dundee, Scotland.;COMSATS Inst Informat Technol, Dept Pharm, Abbottabad, Pakistan.
(author)
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de Borst, Martin H.Univ Groningen, Univ Med Ctr Groningen, Div Nephrol, Dept Internal Med, Groningen, Netherlands.
(author)
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Mangino, MassimoIst Sci San Raffaele, Div Genet & Cell Biol, Milan, Italy.,Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Dept Psychol, Edinburgh, Midlothian, Scotland.,Brigham & Womens Hosp, Div Prevent Med, 75 Francis St, Boston, MA 02115 USA.;Harvard Med Sch, Boston, MA USA.,Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Alzheimer Scotland Dementia Res Ctr, Edinburgh, Midlothian, Scotland.,Broad Inst Harvard & MIT, Cambridge, MA USA.;Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.,Erasmus MC, Genet Epidemiol Unit, Dept Epidemiol, Rotterdam, Netherlands.,Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA USA.;Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA.;Univ Washington, Dept Hlth Serv, Seattle, WA 98195 USA.;Kaiser Permanent, Washington Hlth Res Inst, Seattle, WA USA.
(author)
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Prins, Bram P.Wellcome Trust Sanger Inst, Dept Human Genet, London, England.
(author)
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Campbell, ArchieUniv Edinburgh, Med Genet Sect, Ctr Genom & Expt Med, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Med Genet Sect, Ctr Genom & Expt Med, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Generat Scotland, Ctr Genom & Expt Med, Edinburgh, Midlothian, Scotland.
(author)
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Li-Gao, RuifangLeiden Univ, Med Ctr, Dept Clin Epidemiol, Leiden, Netherlands.
(author)
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Chauhan, GaneshBordeaux Populat Hlth Ctr, INSERM U 1219, Bordeaux, France.;Bordeaux Univ, Bordeaux, France.
(author)
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Oldmeadow, ChristopherHunter Med Res Inst, New Lambton, NSW, Australia.
(author)
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Abecasis, GoncaloCtr Stat Genet, Dept Biostat, Ann Arbor, MI USA.
(author)
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Abedi, MaryamIsfahan Univ Med Sci, Dept Genet & Mol Biol, Esfahan, Iran.
(author)
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Barbieri, Caterina M.
(author)
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Barnes, Michael R.William Harvey Res Inst, Clin Pharmacol, London, England.;Queen Mary Univ London, NIHR Barts Cardiovasc Biomed Res Unit, Barts & London Sch Med & Dent, London, England.
(author)
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Batini, ChiaraUniv Leicester, Dept Hlth Sci, Leicester, Leics, England.
(author)
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Beilby, JohnBusselton Populat Med Res Inst, Nedlands, WA, Australia.;PathWest Lab Med Western Australia, Nedlands, WA, Australia.;Univ Western Australia, Sch Pathol & Lab Med, Nedlands, WA, Australia.
(author)
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Blake, TinekaUniv Leicester, Dept Hlth Sci, Leicester, Leics, England.
(author)
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Boehnke, MichaelUniv Michigan, Dept Biostat, Ann Arbor, MI USA.;Univ Michigan, Ctr Stat Genet, Ann Arbor, MI USA.
(author)
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Bottinger, Erwin P.Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY USA.
(author)
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Braund, Peter S.
(author)
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Brown, MorrisWilliam Harvey Res Inst, Clin Pharmacol, London, England.;Queen Mary Univ London, NIHR Barts Cardiovasc Biomed Res Unit, Barts & London Sch Med & Dent, London, England.,NIA, Intramural Res Program, Lab Epidemiol Demog & Biometry, Bethesda, MD 20892 USA.
(author)
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Brumat, MarcoUniv Trieste, Dept Med Surg & Hlth Sci, Trieste, Italy.
(author)
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Campbell, HarryUniv Edinburgh, Ctr Global Hlth Res, Usher Inst Populat Hlth Sci & Informat, Edinburgh, Midlothian, Scotland.
(author)
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Chambers, John C.Imperial Coll London, Dept Epidemiol & Biostat, Sch Publ Hlth, London, England.;London North West Healthcare NHS Trust, Ealing Hosp, Dept Cardiol, Southall, Middx, England.;Imperial Coll Healthcare NHS Trust, London, England.,Univ Dundee, Ninewells Hosp & Med Sch, Dundee, Scotland.
(author)
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Cocca, MassimilianoUniv Trieste, Dept Med Surg & Hlth Sci, Trieste, Italy.
(author)
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Collins, FrancisNHGRI, Med Genom & Metab Genet Branch, Bethesda, MD 20892 USA.
(author)
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Connell, JohnNewcastle Univ, Inst Med Genet, Newcastle Upon Tyne, Tyne & Wear, England.
(author)
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Cordell, Heather J.
(author)
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Damman, Jeffrey J.Amsterdam Med Ctr, Dept Pathol, Amsterdam, Netherlands.
(author)
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Davies, GailUniv Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Dept Psychol, Edinburgh, Midlothian, Scotland.
(author)
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de Geus, Eco J.Vrije Univ, VU Univ Med Ctr, EMGO Inst, Dept Biol Psychol, Amsterdam, Netherlands.
(author)
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de Mutsert, ReneeLeiden Univ, Med Ctr, Dept Clin Epidemiol, Leiden, Netherlands.
(author)
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Deelen, JorisLeiden Univ, Med Ctr, Dept Mol Epidemiol, Leiden, Netherlands.,Univ Edinburgh, Sch Mol Genet & Populat Hlth Sci, Sch Med, Teviot Pl, Edinburgh, Midlothian, Scotland.
(author)
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Demirkale, YusufNIH, Ctr Informat Technol, Bldg 10, Bethesda, MD 20892 USA.
(author)
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Doney, Alex S. F.Hunter Med Res Inst, New Lambton, NSW, Australia.;Univ Newcastle, Fac Hlth, Callaghan, NSW, Australia.;John Hunter Hosp, New Lambton, NSW, Australia.
(author)
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Dorr, MarcusUniv Med Greifswald, Dept Internal Med, Greifswald, Germany.;Univ Med Greifswald, Interfac Inst Genet & Funct Genom, Greifswald, Germany.;DZHK German Ctr Cardiovasc Res, Greifswald, Germany.
(author)
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Farrall, MartinUniv Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Div Cardiovasc Med, Radcliffe Dept Med, Oxford, England.
(author)
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Ferreira, TeresaUniv Tartu, Estonian Genome Ctr, Tartu, Estonia.;Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.
(author)
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Frånberg, MattiasStockholms universitet,Numerisk analys och datalogi (NADA),Karolinska Institutet, Sweden; Karolinska Universitetsjukhuset, Sweden,Karolinska Inst, Dept Med Solna, Cardiovasc Med Unit, Stockholm, Sweden.;Karolinska Univ, Ctr Mol Med, Solna, Sweden.;Stockholm Univ, Dept Numer Anal & Comp Sci, Stockholm, Sweden.(Swepub:su)mafr3971
(author)
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Gao, HeImperial Coll London, Dept Epidemiol & Biostat, Sch Publ Hlth, London, England.
(author)
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Giedraitis, VilmantasUppsala universitet,Geriatrik(Swepub:uu)vigie517
(author)
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Gieger, ChristianForschungszentrum Gesundheit & Umwelt GmbH, Neuherberg, Germany.
(author)
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Giulianini, FrancoBrigham & Womens Hosp, Div Prevent Med, 75 Francis St, Boston, MA 02115 USA.
(author)
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Gow, Alan J.Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland.;Heriot Watt Univ, Sch Social Sci, Dept Psychol, Edinburgh, Midlothian, Scotland.,Univ Western Australia, Sch Med & Pharmacol, Nedlands, WA, Australia.;Sir Charles Gairdner Hosp, Dept Pulm Physiol & Sleep, Nedlands, WA, Australia.
(author)
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Hamsten, AndersKarolinska Institutet
(author)
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Harris, Tamara B.
(author)
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Hofman, AlbertErasmus MC, Dept Epidemiol, Rotterdam, Netherlands.;Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA.
(author)
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Holliday, Elizabeth G.Hunter Med Res Inst, New Lambton, NSW, Australia.,IRCCS Burlo Garofolo Children Hosp, Med Genet, Trieste, Italy.;Univ Trieste, Dept Med Surg & Hlth Sci, Trieste, Italy.
(author)
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Hui, JennieBusselton Populat Med Res Inst, Nedlands, WA, Australia.;PathWest Lab Med Western Australia, Nedlands, WA, Australia.;Univ Western Australia, Sch Pathol & Lab Med, Nedlands, WA, Australia.;Univ Western Australia, Sch Populat & Global Hlth, Nedlands, WA, Australia.
(author)
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Jarvelin, Marjo-RiittaImperial Coll London, MRC PHE Ctr Environm & Hlth, Dept Epidemiol & Biostat, Sch Publ Hlth, London, England.;Univ Oulu, Ctr Life Course Hlth Res, Oulu, Finland.;Univ Oulu, Bioctr Oulu, Oulu, Finland.;Oulu Univ Hosp, Unit Primary Care, Oulu, Finland.
(author)
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Johansson, ÅsaUppsala universitet,Science for Life Laboratory, SciLifeLab,Medicinsk genetik och genomik(Swepub:uu)asjoh108
(author)
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Johnson, Andrew D.Framingham Heart Dis Epidemiol Study, Natl Heart Lung & Blood Inst, Framingham, MA USA.;NHLBI, Cardiovasc Epidemiol & Human Genom Branch, Bldg 10, Bethesda, MD 20892 USA.
(author)
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Jousilahti, PekkaDept Hlth, Helsinki, Finland. Chron Dis Prevent Unit, Helsinki, Finland. Natl Inst Hlth & Welf, Helsinki, Finland.
(author)
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Jula, AnttiDept Hlth, Helsinki, Finland. Chron Dis Prevent Unit, Helsinki, Finland. Natl Inst Hlth & Welf, Helsinki, Finland.
(author)
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Kahonen, MikaTampere Univ Hosp, Dept Clin Physiol, Tampere, Finland.;Univ Tampere, Dept Clin Physiol, Fac Med & Life Sci, Tampere, Finland.
(author)
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Kathiresan, SekarMassachusetts Gen Hosp, Cardiovasc Res Ctr, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Ctr Human Genet, Boston, MA 02114 USA.;Broad Inst, Program Med & Populat Genet, Cambridge, MA USA.
(author)
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Khaw, Kay-TeeUniv Cambridge, Dept Publ Hlth & Primary Care, Inst Publ Hlth, Cambridge, England.
(author)
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Kolcic, IvanaUniv Split, Dept Publ Hlth, Fac Med, Split, Croatia.
(author)
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Koskinen, SeppoDept Hlth, Helsinki, Finland. Chron Dis Prevent Unit, Helsinki, Finland. Natl Inst Hlth & Welf, Helsinki, Finland.
(author)
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Langenberg, ClaudiaUniv Cambridge, MRC Epidemiol Unit, Sch Clin Med, Inst Metab Sci, Cambridge, England.
(author)
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Larson, MartyFramingham Heart Dis Epidemiol Study, Natl Heart Lung & Blood Inst, Framingham, MA USA.
(author)
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Launer, Lenore J.NIA, Intramural Res Program, Lab Epidemiol Demog & Biometry, Bethesda, MD 20892 USA.
(author)
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Lehne, BenjaminImperial Coll London, Dept Epidemiol & Biostat, Sch Publ Hlth, London, England.
(author)
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Liewald, David C. M.Newcastle Univ, Inst Hlth & Soc, Newcastle Upon Tyne, Tyne & Wear, England.,McMaster Univ, Populat Hlth Res Inst, Hamilton, ON, Canada.,CNR, Inst Genet & Biophys A Buzzati Traverso, Naples, Italy.;IRCCS Neuromed, Pozzilli, Isernia, Italy.
(author)
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Lin, Li
(author)
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Lind, Lars
(author)
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Mach, FrancoisUniv Hosp Geneva, Dept Med Specialties, Cardiol, Geneva, Switzerland.
(author)
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Mamasoula, Chrysovalanto
(author)
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Menni, Cristina
(author)
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Mifsud, BorbalaWilliam Harvey Res Inst, Clin Pharmacol, London, England.
(author)
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Milaneschi, YuriVrije Univ Amsterdam Med Ctr, EMGO Inst Hlth & Care Res, Dept Psychiat, Amsterdam, Netherlands.
(author)
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Morgan, AnnaUniv Trieste, Dept Med Surg & Hlth Sci, Trieste, Italy.
(author)
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Morris, Andrew D.
(author)
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Morrison, Alanna C.Univ Texas Hlth Sci Ctr Houston, Dept Epidemiol Human Genet & Environm Sci, Sch Publ Hlth, Houston, TX USA.
(author)
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Munson, Peter J.NIH, Ctr Informat Technol, Bldg 10, Bethesda, MD 20892 USA.
(author)
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Nandakumar, PriyankaJohns Hopkins Univ, McKusick Nathans Inst Genet Med, Ctr Complex Dis Genom, Sch Med, Baltimore, MD USA.
(author)
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Quang, Tri
(author)
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Nutile, TeresaCNR, Inst Genet & Biophys A Buzzati Traverso, Naples, Italy.
(author)
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Oldehinkel, Albertine J.Univ Groningen, Univ Med Ctr Groningen, Interdisciplinary Ctr Psychopathol & Emot Regulat, Groningen, Netherlands.
(author)
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Oostra, Ben A.Erasmus MC, Genet Epidemiol Unit, Dept Epidemiol, Rotterdam, Netherlands.
(author)
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Org, ElinUniv Tartu, Estonian Genome Ctr, Tartu, Estonia.
(author)
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Padmanabhan, SandoshUniv Edinburgh, Generat Scotland, Ctr Genom & Expt Med, Edinburgh, Midlothian, Scotland.;Univ Glasgow, British Heart Fdn, Glasgow Cardiovasc Res Ctr, Inst Cardiovasc & Med Sci,Coll Med Vet & Life Sci, Glasgow, Lanark, Scotland.;Univ Glasgow, Inst Cardiovasc & Med Sci, Fac Med, Glasgow, Lanark, Scotland.
(author)
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Palotie, AarnoUniv Helsinki, Inst Mol Med Finland FIMM, Helsinki, Finland.
(author)
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Pare, GuillaumeMcMaster Univ, Dept Pathol & Mol Med, Hamilton, ON, Canada.
(author)
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Pattie, AlisonUniv Edinburgh, Dept Psychol, Edinburgh, Midlothian, Scotland.
(author)
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Penninx, Brenda W. J. H.Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Div Cardiovasc Med, Radcliffe Dept Med, Oxford, England.,Leiden Univ, Med Ctr, Dept Cardiol, Leiden, Netherlands.
(author)
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Poulter, NeilImperial Coll London, Sch Publ Hlth, London, England.
(author)
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Pramstaller, Peter P.Univ Lubeck, Inst Biomed, Affiliated Inst, Eurac Res, Bolzano, Italy.;Dept Neurol, Gen Cent Hosp, Bolzano, Italy.;Univ Lubeck, Dept Neurol, Lubeck, Germany.,St Georges Univ London, Populat Hlth Res Inst, London, England.,Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Liverpool, Dept Biostat, Liverpool, Merseyside, England.
(author)
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Raitakari, Olli T.Turku Univ Hosp, Dept Clin Physiol & Nucl Med, Turku, Finland.;Univ Turku, Res Ctr Appl & Prevent Cardiovasc Med, Turku, Finland.
(author)
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Ren, MeixiaWilliam Harvey Res Inst, Clin Pharmacol, London, England.;Fujian Med Univ, Fujian Prov Hosp, Dept Cardiol, Fuzhou, Fujian, Peoples R China.
(author)
-
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Ridker, Paul M.
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Riese, HarrietteUniv Groningen, Univ Med Ctr Groningen, Interdisciplinary Ctr Psychopathol & Emot Regulat, Groningen, Netherlands.
(author)
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Ripatti, SamuliUniv Helsinki, Inst Mol Med Finland FIMM, Helsinki, Finland.
(author)
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Robino, AntoniettaInst Maternal & Child Hlth IRCCS Burlo Garofolo, Trieste, Italy.
(author)
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Rotter, Jerome I.Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Dept Pediat & Med, LABioMed, Torrance, CA USA.
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Rudan, IgorUniv Edinburgh, Ctr Global Hlth Res, Usher Inst Populat Hlth Sci & Informat, Edinburgh, Midlothian, Scotland.
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Saba, YasamanMed Univ Graz, Ctr Mol Med, Inst Mol Biol & Biochem, Graz, Austria.
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Saint Pierre, AudeUniv Lubeck, Inst Biomed, Affiliated Inst, Eurac Res, Bolzano, Italy.;INSERM U1078, Etab Francais Sang, Brest, France.
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Sala, Cinzia F.Ist Sci San Raffaele, Div Genet & Cell Biol, Milan, Italy.
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Sarin, Antti-PekkaUniv Helsinki, Inst Mol Med Finland FIMM, Helsinki, Finland.
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Schmidt, ReinholdMed Univ Graz, Clin Div Neurogeriatr, Dept Neurol, Graz, Austria.
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Scott, Rodney
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Seelen, Marc A.Univ Groningen, Univ Med Ctr Groningen, Div Nephrol, Dept Internal Med, Groningen, Netherlands.
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Shields, Denis C.Univ Coll Dublin, Sch Med, Conway Inst, Belfield, Ireland.
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Siscovick, DavidNew York Acad Med, New York, NY USA.
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Sorice, RossellaCNR, Inst Genet & Biophys A Buzzati Traverso, Naples, Italy.;IRCCS Neuromed, Pozzilli, Isernia, Italy.
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Stanton, AliceRoyal Coll Surgeons Ireland, Mol & Cellular Therapeut, Dublin 2, Ireland.
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Stott, David J.Univ Glasgow, Inst Cardiovasc & Med Sci, Fac Med, Glasgow, Lanark, Scotland.
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Sundström, JohanUppsala universitet,Kardiovaskulär epidemiologi(Swepub:uu)johasund
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Swertz, MorrisUniv Groningen, Univ Med Ctr Groningen, Dept Genet, Groningen, Netherlands.
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Taylor, Kent D.Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Los Angeles BioMed Res Inst, Torrance, CA USA.;Harbor UCLA Med Ctr, Div Genet Outcomes, Dept Pediat, Torrance, CA USA.
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Thom, SimonImperial Coll London, Int Ctr Circulatory Hlth, London, England.
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Tzoulaki, IoannaImperial Coll London, Dept Epidemiol & Biostat, Sch Publ Hlth, London, England.
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Tzourio, ChristopheBordeaux Populat Hlth Ctr, INSERM U 1219, Bordeaux, France.;Bordeaux Univ, Bordeaux, France.;Bordeaux Univ Hosp, Dept Publ Hlth, Bordeaux, France.;Bordeaux Univ Hosp, Dept Neurol, Bordeaux, France.
(author)
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Uitterlinden, Andre G.Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands.;Erasmus MC, Dept Internal Med, Rotterdam, Netherlands.
(author)
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Volker, UweUniv Med Greifswald, Interfac Inst Genet & Funct Genom, Greifswald, Germany.;DZHK German Ctr Cardiovasc Res, Greifswald, Germany.
(author)
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Vollenweider, PeterUniv Lausanne Hosp, CHUV, Dept Internal Med, Lausanne, Switzerland.
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Wild, SarahUniv Edinburgh, Ctr Global Hlth Res, Usher Inst Populat Hlth Sci & Informat, Edinburgh, Midlothian, Scotland.
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Willemsen, GonnekeVrije Univ, VU Univ Med Ctr, EMGO Inst, Dept Biol Psychol, Amsterdam, Netherlands.
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Wright, Alan F.Univ Edinburgh, MRC Human Genet Unit, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Western Gen Hosp, MRC Human Genet Unit, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.
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Yao, JieHarbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Dept Pediat, Torrance, CA USA.
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Theriault, SebastienMcMaster Univ, Dept Pathol & Mol Med, Hamilton, ON, Canada.
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Attia, JohnHunter Med Res Inst, New Lambton, NSW, Australia.;Univ Newcastle, Fac Hlth, Callaghan, NSW, Australia.;John Hunter Hosp, New Lambton, NSW, Australia.
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Sever, Peter
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Debette, StephanieBordeaux Populat Hlth Ctr, INSERM U 1219, Bordeaux, France.;Bordeaux Univ, Bordeaux, France.;Bordeaux Univ Hosp, Dept Neurol, Bordeaux, France.
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Mook-Kanamori, Dennis O.Leiden Univ, Med Ctr, Dept Clin Epidemiol, Leiden, Netherlands.;Leiden Univ, Med Ctr, Dept Publ Hlth & Primary Care, Leiden, Netherlands.
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Zeggini, EleftheriaWellcome Trust Sanger Inst, Dept Human Genet, London, England.
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Spector, Tim D.
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van der Harst, PimUniv Groningen, Univ Med Ctr Groningen, Dept Cardiol, Groningen, Netherlands.
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Palmer, Colin N. A.Columbia Univ, Dept Med, Med Ctr, New York, NY USA.
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Vergnaud, Anne-ClaireImperial Coll London, Dept Epidemiol & Biostat, Sch Publ Hlth, London, England.
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Loos, Ruth J. F.Univ Cambridge, MRC Epidemiol Unit, Sch Clin Med, Inst Metab Sci, Cambridge, England.;Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY USA.;Icahn Sch Med Mt Sinai, Mindich Child Hlth Dev Inst, New York, NY USA.
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Polasek, OzrenUniv Split, Dept Publ Hlth, Fac Med, Split, Croatia.
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Starr, John M.
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Girotto, Giorgia
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Hayward, CarolineUniv Edinburgh, Generat Scotland, Ctr Genom & Expt Med, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, MRC, Human Genet Unit, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.
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Kooner, Jaspal S.
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Lindgren, Cecila M.
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Vitart, Veronique
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Samani, Nilesh J.Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Univ Leicester, NIHR Leicester Biomed Res Ctr, Leicester, Leics, England.;Glenfield Hosp, NIHR Leicester Cardiovasc Biomed Res Unit, Leicester, Leics, England.;Univ Edinburgh, Western Gen Hosp, MRC Human Genet Unit, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.
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Tuomilehto, JaakkoDasman Diabet Inst, Kuwait, Kuwait.;King Abdulaziz Univ, Diabet Res Grp, Jeddah, Saudi Arabia.;Danube Univ Krems, Dept Neurosci & Prevent Med, Krems An Der Donau, Austria. Univ Manchester, Div Cardiovasc Sci, Manchester, Lancs, England.
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Gyllensten, UlfUppsala universitet,Science for Life Laboratory, SciLifeLab,Medicinsk genetik och genomik(Swepub:uu)ulfgyll
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Knekt, PaulDept Hlth, Helsinki, Finland. Chron Dis Prevent Unit, Helsinki, Finland. Natl Inst Hlth & Welf, Helsinki, Finland.
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Deary, Ian J.Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Dept Psychol, Edinburgh, Midlothian, Scotland.
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Ciullo, Marina
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Elosua, RobertoIMIM, Cardiovasc Epidemiol & Genet, Barcelona, Spain.;CIBERCV, Barcelona, Spain.
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Keavney, Bernard D.Cent Manchester Univ Hosp NHS Fdn Trust, Manchester, Lancs, England.
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Hicks, Andrew A.Univ Lubeck, Inst Biomed, Affiliated Inst, Eurac Res, Bolzano, Italy.
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Scott, Robert A.Univ Cambridge, MRC Epidemiol Unit, Sch Clin Med, Inst Metab Sci, Cambridge, England.
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Gasparini, PaoloIRCCS Burlo Garofolo Children Hosp, Med Genet, Trieste, Italy.;Univ Trieste, Dept Med Surg & Hlth Sci, Trieste, Italy.
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Laan, MarisUniv Tartu, Inst Biomed & Translat Med, Tartu, Estonia.
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Liu, YongMeiWake Forest Sch Med, Div Publ Hlth Sci, Winston Salem, NC USA.
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Watkins, Hugh
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Hartman, Catharina A.Univ Groningen, Univ Med Ctr Groningen, Interdisciplinary Ctr Psychopathol & Emot Regulat, Groningen, Netherlands.
(author)
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Salomaa, VeikkoDept Hlth, Helsinki, Finland. Chron Dis Prevent Unit, Helsinki, Finland. Natl Inst Hlth & Welf, Helsinki, Finland.
(author)
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Toniolo, DanielaIst Sci San Raffaele, Div Genet & Cell Biol, Milan, Italy.
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Perola, MarkusUniv Tartu, Estonian Genome Ctr, Tartu, Estonia.;Dept Hlth, Helsinki, Finland. Chron Dis Prevent Unit, Helsinki, Finland. Natl Inst Hlth & Welf, Helsinki, Finland.;Univ Helsinki, Inst Mol Med Finland FIMM, Helsinki, Finland.
(author)
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Wilson, James F.Univ Edinburgh, Ctr Global Hlth Res, Usher Inst Populat Hlth Sci & Informat, Edinburgh, Midlothian, Scotland.
(author)
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Schmidt, HelenaMed Univ Graz, Dept Neurol, Graz, Austria.;Med Univ Graz, Ctr Mol Med, Inst Mol Biol & Biochem, Graz, Austria.
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Zhao, Jing HuaUniv Cambridge, MRC Epidemiol Unit, Sch Clin Med, Inst Metab Sci, Cambridge, England.
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Lehtimaki, TerhoFimlab Labs, Dept Clin Chem, Tampere, Finland.;Univ Tampere, Fac Med & Life Sci, Dept Clin Chem, Tampere, Finland.
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van Duijn, Cornelia M.
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Gudnason, VilmundurIcelandic Heart Assoc, Kopavogur, Iceland.;Univ Iceland, Fac Med, Reykjavik, Iceland.
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Psaty, Bruce M.
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Peters, AnnetteHelmholtz Zentrum Munchen, Inst Epidemiol 2, Munich, Germany.
(author)
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Rettig, Rainer
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James, Alan
(author)
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Jukema, J. Wouter
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Strachan, David P.
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Palmas, Walter
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Metspalu, AndresUniv Tartu, Estonian Genome Ctr, Tartu, Estonia.
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Ingelsson, Erik,1975-Uppsala universitet,Molekylär epidemiologi,Science for Life Laboratory, SciLifeLab(Swepub:uu)ering425
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Boomsma, Dorret I.Vrije Univ, VU Univ Med Ctr, EMGO Inst, Dept Biol Psychol, Amsterdam, Netherlands.
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Franco, Oscar H.Erasmus MC, Dept Epidemiol, Rotterdam, Netherlands.
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Bochud, MurielleUniv Lausanne Hosp, Inst Social & Prevent Med, Lausanne, Switzerland.
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Newton-Cheh, ChristopherBroad Inst Harvard & MIT, Cambridge, MA USA.;Massachusetts Gen Hosp, Cardiovasc Res Ctr, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USA.;Broad Inst, Program Med & Populat Genet, Cambridge, MA USA.
(author)
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Munroe, Patricia B.William Harvey Res Inst, Clin Pharmacol, London, England.;Queen Mary Univ London, NIHR Barts Cardiovasc Biomed Res Unit, Barts & London Sch Med & Dent, London, England.
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Elliott, PaulImperial Coll London, MRC PHE Ctr Environm & Hlth, Dept Epidemiol & Biostat, Sch Publ Hlth, London, England.
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Chasman, Daniel I.Brigham & Womens Hosp, Div Prevent Med, 75 Francis St, Boston, MA 02115 USA.;Harvard Med Sch, Boston, MA USA.
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Chakravarti, AravindaJohns Hopkins Univ, McKusick Nathans Inst Genet Med, Ctr Complex Dis Genom, Sch Med, Baltimore, MD USA.
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Knight, JoanneUniv Lancaster, Data Sci Inst, Lancaster, England.;Univ Lancaster, Lancaster Med Sch, Lancaster, England.
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Morris, Andrew P.
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Levy, DanielNHLBI, Populat Sci Branch, Div Intramural Res, Bldg 10, Bethesda, MD 20892 USA.;Framingham Heart Dis Epidemiol Study, Framingham, MA USA.
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Tobin, Martin D.
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Snieder, HaroldUniv Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands.
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Caulfield, Mark J.William Harvey Res Inst, Clin Pharmacol, London, England.;Queen Mary Univ London, NIHR Barts Cardiovasc Biomed Res Unit, Barts & London Sch Med & Dent, London, England.
(author)
-
Ehret, Georg B.Johns Hopkins Univ, McKusick Nathans Inst Genet Med, Ctr Complex Dis Genom, Sch Med, Baltimore, MD USA.;Univ Hosp Geneva, Dept Med Specialties, Cardiol, Geneva, Switzerland.
(author)
-
Alistair, T. Y.
(author)
-
Betholdson, J. -P.
(author)
-
Xiao, Limin
(author)
-
Univ Leicester, Dept Hlth Sci, Leicester, Leics, England.Univ Edinburgh, MRC Human Genet Unit, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Western Gen Hosp, MRC Human Genet Unit, Inst Genet & Mol Med, Edinburgh, Midlothian, Scotland.
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Hypertension
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Karolinska Institutet