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Blood n-3 fatty aci...
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Harris, WSUniv South Dakota, Sanford Sch Med, Dept Internal Med, Sioux Falls, SD 57105 USA.;Fatty Acid Res Inst, Sioux Falls, SD 57106 USA.
(author)
Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies
- Article/chapterEnglish2021
Publisher, publication year, extent ...
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2021-04-22
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Springer Science and Business Media LLC,2021
Numbers
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LIBRIS-ID:oai:prod.swepub.kib.ki.se:146524233
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http://kipublications.ki.se/Default.aspx?queryparsed=id:146524233URI
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https://doi.org/10.1038/s41467-021-22370-2DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-443480URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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The health effects of omega-3 fatty acids have been controversial. Here we report the results of a de novo pooled analysis conducted with data from 17 prospective cohort studies examining the associations between blood omega-3 fatty acid levels and risk for all-cause mortality. Over a median of 16 years of follow-up, 15,720 deaths occurred among 42,466 individuals. We found that, after multivariable adjustment for relevant risk factors, risk for death from all causes was significantly lower (by 15–18%, at least p < 0.003) in the highest vs the lowest quintile for circulating long chain (20–22 carbon) omega-3 fatty acids (eicosapentaenoic, docosapentaenoic, and docosahexaenoic acids). Similar relationships were seen for death from cardiovascular disease, cancer and other causes. No associations were seen with the 18-carbon omega-3, alpha-linolenic acid. These findings suggest that higher circulating levels of marine n-3 PUFA are associated with a lower risk of premature death.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Tintle, NLFatty Acid Res Inst, Sioux Falls, SD 57106 USA.;Dordt Univ, Dept Math & Stat, Sioux Ctr, IA USA.
(author)
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Imamura, FUniv Cambridge, MRC Epidemiol Unit, Sch Clin Med, Cambridge, England.
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Qian, FHarvard TH Chan Sch Publ Hlth, Dept Nutr, Boston, MA USA.;Harvard Med Sch, Boston, MA 02115 USA.;Brigham & Womens Hosp, Dept Med, 75 Francis St, Boston, MA 02115 USA.
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Korat, AVAHarvard Med Sch, Boston, MA 02115 USA.;Brigham & Womens Hosp, Dept Med, 75 Francis St, Boston, MA 02115 USA.
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Marklund, MHarvard Med Sch, Boston, MA 02115 USA.;Univ New South Wales, George Inst Global Hlth, Sydney, NSW, Australia.;Univ New South Wales, Fac Med, Sydney, NSW, Australia.;Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidmiol, Baltimore, MD USA.,Wageningen Univ, Div Human Nutr & Hlth, Wageningen, Netherlands.,Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA 98104 USA.,Univ Minnesota, Sch Publ Hlth, Div Epidemiol & Community Hlth, Minneapolis, MN USA.
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Djousse, LBrigham & Womens Hosp, Dept Med, 75 Francis St, Boston, MA 02115 USA.
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Bassett, JKHarvard Med Sch, Boston, MA 02115 USA.;Canc Council Victoria, Canc Epidmiol Div, Melbourne, Vic, Australia.
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Carmichael, PHCIUSSS CN, Ctr Excellence Vieillissement Quebec, Quebec City, PQ, Canada.
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Chen, YYNatl Taiwan Univ, Taipei Vet Gen Hosp, Dept Med, Taipei, Taiwan.;Natl Taiwan Univ, Inst Epidemiol & Prevent Med, Taipei, Taiwan.
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Hirakawa, YKyushu Univ, Grad Sch Med Sci, Dept Med & Clin Sci, Fukuoka, Japan.,Univ New South Wales, George Inst Global Hlth, Sydney, NSW, Australia.;Univ New South Wales, Fac Med, Sydney, NSW, Australia.
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Kupers, LKKarolinska Institutet
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Laguzzi, FKarolinska Institutet,Karolinska Inst, Inst Environm Med, Stockholm, Sweden.
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Lankinen, MUniv Eastern Finland, Inst Publ Hlth & Clin Nutr, Kuopio, Finland.
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Murphy, RABC Canc Agcy, Canc Control Res, Vancouver, BC, Canada.;Univ British Columbia, Sch Populat & Publ Hlth, Vancouver, BC, Canada.
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Samieri, CUniv Bordeaux, Bordeaux Populat Hlth Res Ctr, INSERM, Bordeaux, France.
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Senn, MKBaylor Coll Med, USDA ARS Childrens Nutr Res Ctr, Houston, TX 77030 USA.
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Shi, PLTufts Univ, Freidman Sch Nutr Sci & Policy, Boston, MA 02111 USA.
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Virtanen, JKUniv Eastern Finland, Inst Publ Hlth & Clin Nutr, Kuopio, Finland.
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Brouwer, IAVrije Univ Amsterdam, Fac Sci, Dept Hlth Sci, Amsterdam, Netherlands.;Amsterdam Publ Hlth Res Inst, Amsterdam, Netherlands.
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Chien, KLNatl Taiwan Univ, Inst Epidmiol & Prevent Med, Coll Publ Hlth, Taipei, Taiwan.;Natl Taiwan Univ Hosp, Dept Internal Med, Taipei, Taiwan.
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Eiriksdottir, GIceland Heart Assoc, Kopavogur, Iceland.
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Forouhi, NGUniv Cambridge, MRC Epidemiol Unit, Sch Clin Med, Cambridge, England.
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Geleijnse, JMUniv Eastern Finland, Inst Publ Hlth & Clin Nutr, Kuopio, Finland.
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Giles, GGUniv Melbourne, Ctr Epidmiol & Biostat, Melbourne, Vic, Australia.,Univ Iowa, Dept Med, Iowa City, IA 52242 USA.;Univ Iowa, Dept Epidemiol, Iowa City, IA USA.
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Gudnason, VIceland Heart Assoc, Kopavogur, Iceland.;Univ Iceland, Sch Hlth Sci, Reykjavik, Iceland.
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Helmer, CUniv Bordeaux, Bordeaux Populat Hlth Res Ctr, INSERM, Bordeaux, France.
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Hodge, AUniv Melbourne, Ctr Epidmiol & Biostat, Melbourne, Vic, Australia.,Univ Calif San Diego, Sch Med, Dept Family Med & Publ Hlth, La Jolla, CA 92093 USA.
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Jackson, ROhio State Univ, Dept Internal Med, Div Endocrinol, Columbus, OH 43210 USA.
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Khaw, KTUniv Cambridge, MRC Epidemiol Unit, Sch Clin Med, Cambridge, England.
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Laakso, MUniv Eastern Finland, Inst Clin Med, Kuopio, Finland.
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Lai, HDTufts Univ, Freidman Sch Nutr Sci & Policy, Boston, MA 02111 USA.;Imperial Coll, Dept Primary Care & Publ Hlth, London, England.
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Laurin, DCIUSSS CN, Ctr Excellence Vieillissement Quebec, Quebec City, PQ, Canada.;Laval Univ, VITAM Res Ctr, Quebec City, PQ, Canada.
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Leander, KKarolinska Institutet
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Lindsay, JUniv Ottawa, Sch Epidmiol & Publ Hlth, Ottawa, ON, Canada.
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Micha, RTufts Univ, Freidman Sch Nutr Sci & Policy, Boston, MA 02111 USA.
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Mursu, J
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Ninomiya, TKyushu Univ, Dept Epidmiol & Publ Hlth, Fukuoka, Japan.
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Post, WCanc Council Victoria, Canc Epidmiol Div, Melbourne, Vic, Australia.
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Psaty, BM
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Risérus, Ulf,1967-Uppsala universitet,Klinisk nutrition och metabolism(Swepub:uu)ulfriser
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Robinson, JG
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Shadyab, AH
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Snetselaar, LUniv Iowa, Dept Epidemiol, Iowa City, IA USA.
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Sala-Vila, AFatty Acid Res Inst, Sioux Falls, SD 57106 USA.;Pasqual Maragall Fdn, Hosp del Mar Med Res Inst IMIM, Barcelona, Spain.;Pasqual Maragall Fdn, Barcelona Beta Brain Res, Barcelona, Spain.
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Sun, YBUniv Iowa, Dept Epidemiol, Iowa City, IA USA.;Univ Tennessee, Ctr Hlth Sci, Dept Prevent Med, Memphis, TN 38163 USA.
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Steffen, LM
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Tsai, MCYUniv Minnesota, Dept Lab Med & Pathol, Minneapolis, MN 55455 USA.
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Wareham, NJUniv Cambridge, MRC Epidemiol Unit, Sch Clin Med, Cambridge, England.
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Wood, ACBaylor Coll Med, USDA ARS Childrens Nutr Res Ctr, Houston, TX 77030 USA.
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Wu, JHY
(author)
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Hu, FHarvard TH Chan Sch Publ Hlth, Dept Nutr, Boston, MA USA.;Harvard Med Sch, Boston, MA 02115 USA.;Brigham & Womens Hosp, Dept Med, 75 Francis St, Boston, MA 02115 USA.
(author)
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Sun, QHarvard TH Chan Sch Publ Hlth, Dept Nutr, Boston, MA USA.;Harvard Med Sch, Boston, MA 02115 USA.;Brigham & Womens Hosp, Dept Med, 75 Francis St, Boston, MA 02115 USA.
(author)
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Siscovick, DSNew York Acad Med, New York, NY USA.
(author)
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Lemaitre, RNUniv Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA 98104 USA.
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Mozaffarian, DTufts Univ, Freidman Sch Nutr Sci & Policy, Boston, MA 02111 USA.
(author)
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Univ South Dakota, Sanford Sch Med, Dept Internal Med, Sioux Falls, SD 57105 USA.;Fatty Acid Res Inst, Sioux Falls, SD 57106 USA.Fatty Acid Res Inst, Sioux Falls, SD 57106 USA.;Dordt Univ, Dept Math & Stat, Sioux Ctr, IA USA.
(creator_code:org_t)
Related titles
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In:Nature communications: Springer Science and Business Media LLC12:1, s. 2329-2041-1723
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Find in a library
To the university's database
- By the author/editor
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Harris, WS
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Tintle, NL
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Imamura, F
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Qian, F
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Korat, AVA
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Marklund, M
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show more...
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Djousse, L
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Bassett, JK
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Carmichael, PH
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Chen, YY
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Hirakawa, Y
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Kupers, LK
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Laguzzi, F
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Lankinen, M
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Murphy, RA
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Samieri, C
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Senn, MK
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Shi, PL
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Virtanen, JK
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Brouwer, IA
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Chien, KL
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Eiriksdottir, G
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Forouhi, NG
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Geleijnse, JM
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Giles, GG
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Gudnason, V
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Helmer, C
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Hodge, A
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Jackson, R
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Khaw, KT
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Laakso, M
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Lai, HD
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Laurin, D
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Leander, K
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Lindsay, J
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Micha, R
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Mursu, J
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Ninomiya, T
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Post, W
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Psaty, BM
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Risérus, Ulf, 19 ...
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Robinson, JG
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Shadyab, AH
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Snetselaar, L
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Sala-Vila, A
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Sun, YB
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Steffen, LM
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Tsai, MCY
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Wareham, NJ
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Wood, AC
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Wu, JHY
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Hu, F
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Sun, Q
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Siscovick, DS
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Lemaitre, RN
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Mozaffarian, D
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Karolinska Institutet
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Uppsala University