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  • Nsekuye, O (author)

Investigation of Four Clusters of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Rwanda, 2020

  • Article/chapterEnglish2021

Publisher, publication year, extent ...

  • 2021-06-30
  • MDPI AG,2021

Numbers

  • LIBRIS-ID:oai:prod.swepub.kib.ki.se:147087054
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:147087054URI
  • https://doi.org/10.3390/ijerph18137018DOI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • We reported the findings of the first Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) four clusters identified in Rwanda. Case-investigations included contact elicitation, testing, and isolation/quarantine of confirmed cases. Socio-demographic and clinical data on cases and contacts were collected. A confirmed case was a person with laboratory confirmation of SARS-CoV-2 infection (PCR) while a contact was any person who had contact with a SARS-CoV-2 confirmed case within 72 h prior, to 14 days after symptom onset; or 14 days before collection of the laboratory-positive sample for asymptomatic cases. High risk contacts were those who had come into unprotected face-to-face contact or had been in a closed environment with a SARS-CoV-2 case for >15 min. Forty cases were reported from four clusters by 22 April 2020, accounting for 61% of locally transmitted cases within six weeks. Clusters A, B, C and D were associated with two nightclubs, one house party, and different families or households living in the same compound (multi-family dwelling). Thirty-six of the 1035 contacts tested were positive (secondary attack rate: 3.5%). Positivity rates were highest among the high-risk contacts compared to low-risk contacts (10% vs. 2.2%). Index cases in three of the clusters were imported through international travelling. Fifteen of the 40 cases (38%) were asymptomatic while 13/25 (52%) and 8/25 (32%) of symptomatic cases had a cough and fever respectively. Gatherings in closed spaces were the main early drivers of transmission. Systematic case-investigations contact tracing and testing likely contributed to the early containment of SARS-CoV-2 in Rwanda.

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Added entries (persons, corporate bodies, meetings, titles ...)

  • Rwagasore, E (author)
  • Muhimpundu, MA (author)
  • El-Khatib, ZKarolinska Institutet (author)
  • Ntabanganyimana, D (author)
  • Kamayirese, EN (author)
  • Ruyange, L (author)
  • Umutoni, A (author)
  • Adeline, AK (author)
  • Ntaganira, J (author)
  • Nsazimana, S (author)
  • Omolo, J (author)
  • Karolinska Institutet (creator_code:org_t)

Related titles

  • In:International journal of environmental research and public health: MDPI AG18:131660-4601

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