Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

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Bastard, P (author)

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Article/chapterEnglish2021

Publisher, publication year, extent ...

American Association for the Advancement of Science (AAAS),2021

Numbers

LIBRIS-ID:oai:prod.swepub.kib.ki.se:147624188
http://kipublications.ki.se/Default.aspx?queryparsed=id:147624188URI
https://doi.org/10.1126/sciimmunol.abl4340DOI
https://gup.ub.gu.se/publication/306513URI

Supplementary language notes

Language:English
Summary in:English

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SwePubSwePub

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Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

Autoantibodies neutralizing type I IFNs increase in prevalence over 60 years of age and underlie about 20% of all fatal COVID-19 cases.

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Gervais, A (author)
Le Voyer, T (author)
Rosain, J (author)
Philippot, Q (author)
Manry, J (author)
Michailidis, E (author)
Hoffmann, HH (author)
Eto, S (author)
Garcia-Prat, M (author)
Bizien, L (author)
Parra-Martinez, A (author)
Yang, R (author)
Haljasmagi, L (author)
Migaud, M (author)
Sarekannu, K (author)
Maslovskaja, J (author)
de Prost, N (author)
Tandjaoui-Lambiotte, Y (author)
Luyt, CE (author)
Amador-Borrero, B (author)
Gaudet, A (author)
Poissy, J (author)
Morel, P (author)
Richard, P (author)
Cognasse, F (author)
Troya, J (author)
Trouillet-Assant, S (author)
Belot, A (author)
Saker, K (author)
Garcon, P (author)
Riviere, JG (author)
Lagier, JC (author)
Gentile, S (author)
Rosen, LB (author)
Shaw, E (author)
Morio, T (author)
Tanaka, J (author)
Dalmau, D (author)
Tharaux, PL (author)
Sene, D (author)
Stepanian, A (author)
Megarbane, B (author)
Triantafyllia, V (author)
Fekkar, A (author)
Heath, JR (author)
Franco, JL (author)
Anaya, JM (author)
Sole-Violan, J (author)
Imberti, L (author)
Biondi, A (author)
Bonfanti, P (author)
Castagnoli, R (author)
Delmonte, OM (author)
Zhang, Y (author)
Snow, AL (author)
Holland, SM (author)
Biggs, CM (author)
Moncada-Velez, M (author)
Arias, AA (author)
Lorenzo, L (author)
Boucherit, S (author)
Coulibaly, B (author)
Anglicheau, D (author)
Planas, AM (author)
Haerynck, F (author)
Duvlis, S (author)
Nussbaum, RL (author)
Ozcelik, T (author)
Keles, S (author)
Bousfiha, AA (author)
El Bakkouri, J (author)
Ramirez-Santana, C (author)
Paul, S (author)
Pan-Hammarstrom, QKarolinska Institutet (author)
Hammarstrom, LKarolinska Institutet (author)
Dupont, A (author)
Kurolap, A (author)
Metz, CN (author)
Aiuti, A (author)
Casari, G (author)
Lampasona, V (author)
Ciceri, F (author)
Barreiros, LA (author)
Dominguez-Garrido, E (author)
Vidigal, M (author)
Zatz, M (author)
van de Beek, D (author)
Sahanic, S (author)
Tancevski, I (author)
Stepanovskyy, Y (author)
Boyarchuk, O (author)
Nukui, Y (author)
Tsumura, M (author)
Vidaur, L (author)
Tangye, SG (author)
Burrel, S (author)
Duffy, D (author)
Quintana-Murci, L (author)
Klocperk, A (author)
Kann, NY (author)
Shcherbina, A (author)
Lau, YL (author)
Leung, D (author)
Coulongeat, M (author)
Marlet, J (author)
Koning, R (author)
Reyes, LF (author)
Chauvineau-Grenier, A (author)
Venet, F (author)
Monneret, G (author)
Nussenzweig, MC (author)
Arrestier, R (author)
Boudhabhay, I (author)
Baris-Feldman, H (author)
Hagin, D (author)
Wauters, J (author)
Meyts, I (author)
Dyer, AH (author)
Kennelly, SP (author)
Bourke, NM (author)
Halwani, R (author)
Sharif-Askari, NS (author)
Dorgham, K (author)
Sallette, J (author)
Sedkaoui, SM (author)
AlKhater, S (author)
Rigo-Bonnin, R (author)
Morandeira, F (author)
Roussel, L (author)
Vinh, DC (author)
Ostrowski, SR (author)
Condino-Neto, A (author)
Prando, C (author)
Bondarenko, A (author)
Spaan, AN (author)
Gilardin, L (author)
Fellay, J (author)
Lyonnet, S (author)
Bilguvar, K (author)
Lifton, RP (author)
Mane, S (author)
Anderson, MS (author)
Boisson, B (author)
Beziat, V (author)
Zhang, SY (author)
Andreakos, E (author)
Hermine, O (author)
Pujol, A (author)
Peterson, P (author)
Mogensen, TH (author)
Rowen, L (author)
Mond, J (author)
Debette, S (author)
de Lamballerie, X (author)
Duval, X (author)
Mentre, F (author)
Zins, M (author)
Soler-Palacin, P (author)
Colobran, R (author)
Gorochov, G (author)
Solanich, X (author)
Susen, S (author)
Martinez-Picado, J (author)
Raoult, D (author)
Vasse, M (author)
Gregersen, PK (author)
Piemonti, L (author)
Rodriguez-Gallego, C (author)
Notarangelo, LD (author)
Su, HC (author)
Kisand, K (author)
Okada, S (author)
Puel, A (author)
Jouanguy, E (author)
Rice, CM (author)
Tiberghien, P (author)
Zhang, Q (author)
Cobat, A (author)
Abel, L (author)
Casanova, JL (author)
Ekwall, Olov,1968Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Extern,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Clinical Sciences, Department of Pediatrics,External,Institute of Medicine, Department of Rheumatology and Inflammation Research(Swepub:gu)xekwol (author)
Karolinska InstitutetInstitutionen för kliniska vetenskaper, Avdelningen för pediatrik (creator_code:org_t)

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In:Science immunology: American Association for the Advancement of Science (AAAS)6:622470-9468

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By the author/editor: Bastard, P; Gervais, A; Le Voyer, T; Rosain, J; Philippot, Q; Manry, J; show more...; Michailidis, E; Hoffmann, HH; Eto, S; Garcia-Prat, M; Bizien, L; Parra-Martinez, ...; Yang, R; Haljasmagi, L; Migaud, M; Sarekannu, K; Maslovskaja, J; de Prost, N; Tandjaoui-Lambio ...; Luyt, CE; Amador-Borrero, ...; Gaudet, A; Poissy, J; Morel, P; Richard, P; Cognasse, F; Troya, J; Trouillet-Assant ...; Belot, A; Saker, K; Garcon, P; Riviere, JG; Lagier, JC; Gentile, S; Rosen, LB; Shaw, E; Morio, T; Tanaka, J; Dalmau, D; Tharaux, PL; Sene, D; Stepanian, A; Megarbane, B; Triantafyllia, V; Fekkar, A; Heath, JR; Franco, JL; Anaya, JM; Sole-Violan, J; Imberti, L; Biondi, A; Bonfanti, P; Castagnoli, R; Delmonte, OM; Zhang, Y; Snow, AL; Holland, SM; Biggs, CM; Moncada-Velez, M; Arias, AA; Lorenzo, L; Boucherit, S; Coulibaly, B; Anglicheau, D; Planas, AM; Haerynck, F; Duvlis, S; Nussbaum, RL; Ozcelik, T; Keles, S; Bousfiha, AA; El Bakkouri, J; Ramirez-Santana, ...; Paul, S; Pan-Hammarstrom, ...; Hammarstrom, L; Dupont, A; Kurolap, A; Metz, CN; Aiuti, A; Casari, G; Lampasona, V; Ciceri, F; Barreiros, LA; Dominguez-Garrid ...; Vidigal, M; Zatz, M; van de Beek, D; Sahanic, S; Tancevski, I; Stepanovskyy, Y; Boyarchuk, O; Nukui, Y; Tsumura, M; Vidaur, L; Tangye, SG; Burrel, S; Duffy, D; Quintana-Murci, ...; Klocperk, A; Kann, NY; Shcherbina, A; Lau, YL; Leung, D; Coulongeat, M; Marlet, J; Koning, R; Reyes, LF; Chauvineau-Greni ...; Venet, F; Monneret, G; Nussenzweig, MC; Arrestier, R; Boudhabhay, I; Baris-Feldman, H; Hagin, D; Wauters, J; Meyts, I; Dyer, AH; Kennelly, SP; Bourke, NM; Halwani, R; Sharif-Askari, N ...; Dorgham, K; Sallette, J; Sedkaoui, SM; AlKhater, S; Rigo-Bonnin, R; Morandeira, F; Roussel, L; Vinh, DC; Ostrowski, SR; Condino-Neto, A; Prando, C; Bondarenko, A; Spaan, AN; Gilardin, L; Fellay, J; Lyonnet, S; Bilguvar, K; Lifton, RP; Mane, S; Anderson, MS; Boisson, B; Beziat, V; Zhang, SY; Andreakos, E; Hermine, O; Pujol, A; Peterson, P; Mogensen, TH; Rowen, L; Mond, J; Debette, S; de Lamballerie, ...; Duval, X; Mentre, F; Zins, M; Soler-Palacin, P; Colobran, R; Gorochov, G; Solanich, X; Susen, S; Martinez-Picado, ...; Raoult, D; Vasse, M; Gregersen, PK; Piemonti, L; Rodriguez-Galleg ...; Notarangelo, LD; Su, HC; Kisand, K; Okada, S; Puel, A; Jouanguy, E; Rice, CM; Tiberghien, P; Zhang, Q; Cobat, A; Abel, L; Casanova, JL; Ekwall, Olov, 19 ...; show less...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Pediatrics

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Rheumatology and ...

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