Search: WFRF:(Weiss Stefan) >
Global, regional, a...
Global, regional, and national burden of Alzheimer's disease and other dementias, 1990-2016 : a systematic analysis for the Global Burden of Disease Study 2016
-
Nichols, Emma (author)
-
Szoeke, Cassandra E. I. (author)
-
Vollset, Stein Emil (author)
-
show more...
-
Abbasi, Nooshin (author)
-
Abd-Allah, Foad (author)
-
Abdela, Jemal (author)
-
Aichour, Miloud Taki Eddine (author)
-
Akinyemi, Rufus O. (author)
-
Alahdab, Fares (author)
-
Asgedom, Solomon W. (author)
-
Awasthi, Ashish (author)
-
Barker-Collo, Suzanne L. (author)
-
Baune, Bernhard T. (author)
-
Bejot, Yannick (author)
-
Belachew, Abate B. (author)
-
Bennett, Derrick A. (author)
-
Bijani, Belete Biadgo Ali (author)
-
Bin Sayeed, Muhammad Shahdaat (author)
-
Brayne, Carol (author)
-
Carpenter, David O. (author)
-
Carvalho, Felix (author)
-
Catala-Lopez, Ferran (author)
-
Cerin, Ester (author)
-
Choi, Jee-Young J. (author)
-
Dang, Ahn K. (author)
-
Degefa, Meaza G. (author)
-
Djalalinia, Shirin (author)
-
Dubey, Manisha (author)
-
Duken, Eyasu Ejeta (author)
-
- Edvardsson, David (author)
- Umeå universitet,Institutionen för omvårdnad,School of Nursing and Midwifery, La Trobe University, Melbourne, VIC, Australia
-
Endres, Matthias (author)
-
Eskandarieh, Sharareh (author)
-
Faro, Andre (author)
-
Farzadfar, Farshad (author)
-
- Fereshtehnejad, Seyed-Mohammad (author)
- Karolinska Institutet
-
Fernandes, Eduarda (author)
-
Filip, Irina (author)
-
Fischer, Florian (author)
-
Gebre, Abadi K. (author)
-
Geremew, Demeke (author)
-
Ghasemi-Kasman, Maryam (author)
-
Gnedovskaya, Elena V. (author)
-
Gupta, Rajeev (author)
-
Hachinski, Vladimir (author)
-
Hagos, Tekleberhan B. (author)
-
Hamidi, Samer (author)
-
Hankey, Graeme J. (author)
-
Haro, Josep M. (author)
-
Hay, Simon I. (author)
-
Irvani, Seyed Sina N. (author)
-
Jha, Ravi P. (author)
-
Jonas, Jost B. (author)
-
Kalani, Rizwan (author)
-
Karch, Andre (author)
-
Kasaeian, Amir (author)
-
Khader, Yousef Saleh (author)
-
Khalil, Ibrahim A. (author)
-
Khan, Ejaz Ahmad (author)
-
Khanna, Tripti (author)
-
Khoja, Tawfik A. M. (author)
-
Khubchandani, Jagdish (author)
-
Kisa, Adnan (author)
-
Kissimova-Skarbek, Katarzyna (author)
-
Kivimaki, Mika (author)
-
Koyanagi, Ai (author)
-
Krohn, Kristopher J. (author)
-
Logroscino, Giancarlo (author)
-
Lorkowski, Stefan (author)
-
Majdan, Marek (author)
-
Malekzadeh, Reza (author)
-
Marz, Winfried (author)
-
Massano, Joao (author)
-
Mengistu, Getnet (author)
-
Meretoja, Atte (author)
-
Mohammadi, Moslem (author)
-
Mohammadi-Khanaposhtani, Maryam (author)
-
Mokdad, Ali H. (author)
-
Mondello, Stefania (author)
-
Moradi, Ghobad (author)
-
Nagel, Gabriele (author)
-
Naghavi, Mohsen (author)
-
Naik, Gurudatta (author)
-
Nguyen, Long H. (author)
-
Nguyen, Trang H. (author)
-
Nirayo, Yirga L. (author)
-
Nixon, Molly R. (author)
-
Ofori-Asenso, Richard (author)
-
Ogbo, Felix A. (author)
-
Olagunju, Andrew T. (author)
-
Owolabi, Mayowa O. (author)
-
Panda-Jonas, Songhomitra (author)
-
Passos, Valeria M. de Azeredo (author)
-
Pereira, David M. (author)
-
Pinilla-Monsalve, Gabriel D. (author)
-
Piradov, Michael A. (author)
-
Pond, Constance D. (author)
-
Poustchi, Hossein (author)
-
Qorbani, Mostafa (author)
-
Radfar, Amir (author)
-
Reiner, Robert C. (author)
-
Robinson, Stephen R. (author)
-
Roshandel, Gholamreza (author)
-
Rostami, Ali (author)
-
Russ, Tom C. (author)
-
Sachdev, Perminder S. (author)
-
Safari, Hosein (author)
-
Safiri, Saeid (author)
-
Sahathevan, Ramesh (author)
-
Salimi, Yahya (author)
-
Satpathy, Maheswar (author)
-
Sawhney, Monika (author)
-
Saylan, Mete (author)
-
Sepanlou, Sadaf G. (author)
-
Shafieesabet, Azadeh (author)
-
Shaikh, Masood A. (author)
-
Sahraian, Mohammad A. (author)
-
Shigematsu, Mika (author)
-
Shiri, Rahman (author)
-
Shiue, Ivy (author)
-
Silva, Joao P. (author)
-
Smith, Mari (author)
-
Sobhani, Soheila (author)
-
Stein, Dan J. (author)
-
Tabares-Seisdedos, Rafael (author)
-
Tovani-Palone, Marcos R. (author)
-
Tran, Bach X. (author)
-
Tran, Tung T. (author)
-
Tsegay, Amanuel T. (author)
-
Ullah, Irfan (author)
-
Venketasubramanian, Narayanaswamy (author)
-
Vlassov, Vasily (author)
-
Wang, Yuan-Pang (author)
-
Weiss, Jordan (author)
-
Westerman, Ronny (author)
-
Wijeratne, Tissa (author)
-
Wyper, Grant M. A. (author)
-
Yano, Yuichiro (author)
-
Yimer, Ebrahim M. (author)
-
Yonemoto, Naohiro (author)
-
Yousefifard, Mahmoud (author)
-
Zaidi, Zoubida (author)
-
Zare, Zohreh (author)
-
Feigin, Valery L. (author)
-
Vos, Theo (author)
-
Murray, Christopher J. L. (author)
-
show less...
-
(creator_code:org_t)
- Elsevier, 2019
- 2019
- English.
-
In: Lancet Neurology. - : Elsevier. - 1474-4422 .- 1474-4465. ; 18:1, s. 88-106
- Related links:
-
https://doi.org/10.1...
-
show more...
-
https://umu.diva-por... (primary) (Raw object)
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
http://kipublication...
-
show less...
Abstract
Subject headings
Close
- Background: The number of individuals living with dementia is increasing, negatively affecting families, communities, and health-care systems around the world. A successful response to these challenges requires an accurate understanding of the dementia disease burden. We aimed to present the first detailed analysis of the global prevalence, mortality, and overall burden of dementia as captured by the Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study 2016, and highlight the most important messages for clinicians and neurologists.Methods: GBD 2016 obtained data on dementia from vital registration systems, published scientific literature and surveys, and data from health-service encounters on deaths, excess mortality, prevalence, and incidence from 195 countries and territories from 1990 to 2016, through systematic review and additional data-seeking efforts. To correct for differences in cause of death coding across time and locations, we modelled mortality due to dementia using prevalence data and estimates of excess mortality derived from countries that were most likely to code deaths to dementia relative to prevalence. Data were analysed by standardised methods to estimate deaths, prevalence, years of life lost (YLLs), years of life lived with disability (YLDs), and disability-adjusted life-years (DALYs; computed as the sum of YLLs and YLDs), and the fractions of these metrics that were attributable to four risk factors that met GBD criteria for assessment (high body-mass index [BMI], high fasting plasma glucose, smoking, and a diet high in sugarsweetened beverages).Findings: In 2016, the global number of individuals who lived with dementia was 43.8 million (95% uncertainty interval [UI] 3 7. 8-51.0), increased from 20.2 million (17. 4-23 5) in 1990. This increase of 117% (95% UI 114-121) contrasted with a minor increase in age-standardised prevalence of 1.7% (1.0-2.4), from 701 cases (95% UI 602-815) per 100 000 population in 1990 to 712 cases (614-828) per 100 000 population in 2016. More women than men had dementia in 2016 (27.0 million, 95% UI 23 .3-31. 4, vs 16.8 million, 14.4-19.6), and dementia was the fifth leading cause of death globally, accounting for 2.4 million (95% UI 2.1-2.8) deaths. Overall, 28.8 million (95% UI 24. 5-34. 0) DALYs were attributed to dementia; 6.4 million (95% UI 3 .4-10. 5) of these could be attributed to the modifiable GBD risk factors of high BMI, high fasting plasma glucose, smoking, and a high intake of sugar-sweetened beverages.Interpretation: The global number of people living with dementia more than doubled from 1990 to 2016, mainly due to increases in population ageing and growth. Although differences in coding for causes of death and the heterogeneity in case-ascertainment methods constitute major challenges to the estimation of the burden of dementia, future analyses should improve on the methods for the correction of these biases. Until breakthroughs are made in prevention or curative treatment, dementia will constitute an increasing challenge to health-care systems worldwide.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Nichols, Emma
-
Szoeke, Cassandr ...
-
Vollset, Stein E ...
-
Abbasi, Nooshin
-
Abd-Allah, Foad
-
Abdela, Jemal
-
show more...
-
Aichour, Miloud ...
-
Akinyemi, Rufus ...
-
Alahdab, Fares
-
Asgedom, Solomon ...
-
Awasthi, Ashish
-
Barker-Collo, Su ...
-
Baune, Bernhard ...
-
Bejot, Yannick
-
Belachew, Abate ...
-
Bennett, Derrick ...
-
Bijani, Belete B ...
-
Bin Sayeed, Muha ...
-
Brayne, Carol
-
Carpenter, David ...
-
Carvalho, Felix
-
Catala-Lopez, Fe ...
-
Cerin, Ester
-
Choi, Jee-Young ...
-
Dang, Ahn K.
-
Degefa, Meaza G.
-
Djalalinia, Shir ...
-
Dubey, Manisha
-
Duken, Eyasu Eje ...
-
Edvardsson, Davi ...
-
Endres, Matthias
-
Eskandarieh, Sha ...
-
Faro, Andre
-
Farzadfar, Farsh ...
-
Fereshtehnejad, ...
-
Fernandes, Eduar ...
-
Filip, Irina
-
Fischer, Florian
-
Gebre, Abadi K.
-
Geremew, Demeke
-
Ghasemi-Kasman, ...
-
Gnedovskaya, Ele ...
-
Gupta, Rajeev
-
Hachinski, Vladi ...
-
Hagos, Tekleberh ...
-
Hamidi, Samer
-
Hankey, Graeme J ...
-
Haro, Josep M.
-
Hay, Simon I.
-
Irvani, Seyed Si ...
-
Jha, Ravi P.
-
Jonas, Jost B.
-
Kalani, Rizwan
-
Karch, Andre
-
Kasaeian, Amir
-
Khader, Yousef S ...
-
Khalil, Ibrahim ...
-
Khan, Ejaz Ahmad
-
Khanna, Tripti
-
Khoja, Tawfik A. ...
-
Khubchandani, Ja ...
-
Kisa, Adnan
-
Kissimova-Skarbe ...
-
Kivimaki, Mika
-
Koyanagi, Ai
-
Krohn, Kristophe ...
-
Logroscino, Gian ...
-
Lorkowski, Stefa ...
-
Majdan, Marek
-
Malekzadeh, Reza
-
Marz, Winfried
-
Massano, Joao
-
Mengistu, Getnet
-
Meretoja, Atte
-
Mohammadi, Mosle ...
-
Mohammadi-Khanap ...
-
Mokdad, Ali H.
-
Mondello, Stefan ...
-
Moradi, Ghobad
-
Nagel, Gabriele
-
Naghavi, Mohsen
-
Naik, Gurudatta
-
Nguyen, Long H.
-
Nguyen, Trang H.
-
Nirayo, Yirga L.
-
Nixon, Molly R.
-
Ofori-Asenso, Ri ...
-
Ogbo, Felix A.
-
Olagunju, Andrew ...
-
Owolabi, Mayowa ...
-
Panda-Jonas, Son ...
-
Passos, Valeria ...
-
Pereira, David M ...
-
Pinilla-Monsalve ...
-
Piradov, Michael ...
-
Pond, Constance ...
-
Poustchi, Hossei ...
-
Qorbani, Mostafa
-
Radfar, Amir
-
Reiner, Robert C ...
-
Robinson, Stephe ...
-
Roshandel, Ghola ...
-
Rostami, Ali
-
Russ, Tom C.
-
Sachdev, Permind ...
-
Safari, Hosein
-
Safiri, Saeid
-
Sahathevan, Rame ...
-
Salimi, Yahya
-
Satpathy, Mahesw ...
-
Sawhney, Monika
-
Saylan, Mete
-
Sepanlou, Sadaf ...
-
Shafieesabet, Az ...
-
Shaikh, Masood A ...
-
Sahraian, Mohamm ...
-
Shigematsu, Mika
-
Shiri, Rahman
-
Shiue, Ivy
-
Silva, Joao P.
-
Smith, Mari
-
Sobhani, Soheila
-
Stein, Dan J.
-
Tabares-Seisdedo ...
-
Tovani-Palone, M ...
-
Tran, Bach X.
-
Tran, Tung T.
-
Tsegay, Amanuel ...
-
Ullah, Irfan
-
Venketasubramani ...
-
Vlassov, Vasily
-
Wang, Yuan-Pang
-
Weiss, Jordan
-
Westerman, Ronny
-
Wijeratne, Tissa
-
Wyper, Grant M. ...
-
Yano, Yuichiro
-
Yimer, Ebrahim M ...
-
Yonemoto, Naohir ...
-
Yousefifard, Mah ...
-
Zaidi, Zoubida
-
Zare, Zohreh
-
Feigin, Valery L ...
-
Vos, Theo
-
Murray, Christop ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Health Sciences
-
and Public Health Gl ...
- Articles in the publication
-
Lancet Neurology
- By the university
-
Umeå University
-
Karolinska Institutet