SwePub
Sök i LIBRIS databas

  Extended search

WFRF:(Sia CH)
 

Search: WFRF:(Sia CH) > Internal cerebral v...

  • Myint, MZ (author)

Internal cerebral vein asymmetry is an independent predictor of poor functional outcome in endovascular thrombectomy

  • Article/chapterEnglish2022

Publisher, publication year, extent ...

  • 2021-08-05
  • BMJ,2022

Numbers

  • LIBRIS-ID:oai:prod.swepub.kib.ki.se:148232459
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:148232459URI
  • https://doi.org/10.1136/neurintsurg-2021-017684DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Endovascular thrombectomy (EVT) in large vessel occlusion (LVO) in anterior circulation acute ischaemic stroke (AIS) results in good functional outcomes in only approximately 60% of the patients. Internal cerebral veins (ICVs) are easily visible, with a consistent midline location, and are linked to stroke outcomes. We hypothesize that ICV asymmetry on multiphasic CT angiogram (mCTA) can be an adjunctive predictor for poor functional outcomes.MethodsWe studied consecutive AIS patients from 2017 to 2019 with anterior circulation LVO treated with EVT regardless of intravenous thrombolysis. Asymmetrical ICV was defined as the presence of hypodensity (less opacification) on the ipsilateral occlusion side as compared with the contralateral side. The primary outcome was modified Rankin Score (mRS) score at 3 months. Secondary outcomes were good recanalization (modified Thrombolysis In Cerebral Infarction (mTICI) 2b-3), symptomatic hemorrhage, and mortality.ResultsA total of 185 patients were included with a median age of 70 years (IQR 59–77); 87 patients (47%) were female. 82 patients (44.3%) achieved good functional outcomes (mRS 0–2) at 3 months. On multivariate analysis, National Institutes of Health Stroke Scale (NIHSS) (OR 1.076, 95% CI 1.015 to 1.140; p<0.013), poor collateral score (OR 0.285, 95% CI 0.162 to 0.501; p<0.001), asymmetrical ICV on the peak venous phase (OR 2.47, 95% CI 1.115 to 5.471; p<0.026), and late venous phase of the mCTA (OR 2.642, 95% CI 1.161 to 6.016; p<0.021) were independent risks factors of poor outcomes.ConclusionICV asymmetry is a novel radiological sign which is independently associated with poor functional outcomes in EVT, even after correction for collateral circulation. Further studies are needed to validate this finding.

Added entries (persons, corporate bodies, meetings, titles ...)

  • Yeo, LLLKarolinska Institutet (author)
  • Tan, BYQ (author)
  • The, EZ (author)
  • Lim, MC (author)
  • Sia, CH (author)
  • Teoh, HL (author)
  • Sharma, VK (author)
  • Chan, BA (author)
  • Ahmad, A (author)
  • Paliwal, P (author)
  • Gopinathan, A (author)
  • Yang, CL (author)
  • Makmur, A (author)
  • Andersson, TKarolinska Institutet (author)
  • Arnberg, FKarolinska Institutet (author)
  • Holmin, SKarolinska Institutet (author)
  • Karolinska Institutet (creator_code:org_t)

Related titles

  • In:Journal of neurointerventional surgery: BMJ14:7, s. 683-6871759-84861759-8478

Internet link

Find in a library

To the university's database

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view