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Brain charts for th...
Brain charts for the human lifespan
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- Bethlehem, RAI (author)
- University of Cambridge
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Seidlitz, J (author)
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White, SR (author)
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show more...
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Vogel, JW (author)
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Anderson, KM (author)
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Adamson, C (author)
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Adler, S (author)
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Alexopoulos, GS (author)
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Anagnostou, E (author)
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Areces-Gonzalez, A (author)
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Astle, DE (author)
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- Auyeung, B (author)
- The Children's Hospital of Philadelphia,University of Pennsylvania
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Ayub, M (author)
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Bae, J (author)
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Ball, G (author)
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Baron-Cohen, S (author)
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Beare, R (author)
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Bedford, SA (author)
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Benegal, V (author)
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Beyer, F (author)
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Blangero, J (author)
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Cabez, MB (author)
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Boardman, JP (author)
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Borzage, M (author)
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Bosch-Bayard, JF (author)
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Bourke, N (author)
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Calhoun, VD (author)
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Chakravarty, MM (author)
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Chen, C (author)
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Chertavian, C (author)
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Chetelat, G (author)
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Chong, YS (author)
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Cole, JH (author)
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Corvin, A (author)
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Costantino, M (author)
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Courchesne, E (author)
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Crivello, F (author)
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Cropley, VL (author)
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Crosbie, J (author)
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Crossley, N (author)
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Delarue, M (author)
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Delorme, R (author)
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Desrivieres, S (author)
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Devenyi, GA (author)
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Di Biase, MA (author)
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Dolan, R (author)
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Donald, KA (author)
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Donohoe, G (author)
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Dunlop, K (author)
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Edwards, AD (author)
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Elison, JT (author)
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Ellis, CT (author)
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Elman, JA (author)
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Eyler, L (author)
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Fair, DA (author)
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Feczko, E (author)
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Fletcher, PC (author)
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Fonagy, P (author)
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Franz, CE (author)
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Galan-Garcia, L (author)
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Gholipour, A (author)
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Giedd, J (author)
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Gilmore, JH (author)
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Glahn, DC (author)
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Goodyer, IM (author)
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Grant, PE (author)
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Groenewold, NA (author)
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Gunning, FM (author)
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Gur, RE (author)
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Gur, RC (author)
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Hammill, CF (author)
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- Hansson, O. (author)
- Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups
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Hedden, T (author)
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Heinz, A (author)
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Henson, RN (author)
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Heuer, K (author)
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Hoare, J (author)
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Holla, B (author)
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Holmes, AJ (author)
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Holt, R (author)
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Huang, H (author)
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Im, K (author)
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Ipser, J (author)
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Jack, CR (author)
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Jackowski, AP (author)
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Jia, T (author)
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Johnson, KA (author)
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Jones, PB (author)
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Jones, DT (author)
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Kahn, RS (author)
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Karlsson, H (author)
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Karlsson, L (author)
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Kawashima, R (author)
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Kelley, EA (author)
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- Kern, Silke (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Centrum för åldrande och hälsa (AgeCap),Institute of Neuroscience and Physiology,Centre for Ageing and Health (Agecap)
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Kim, KW (author)
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Kitzbichler, MG (author)
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Kremen, WS (author)
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Lalonde, F (author)
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Landeau, B (author)
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Lee, S (author)
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Lerch, J (author)
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Lewis, JD (author)
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Li, J (author)
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Liao, W (author)
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Liston, C (author)
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Lombardo, MV (author)
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Lv, J (author)
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Lynch, C (author)
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Mallard, TT (author)
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Marcelis, M (author)
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Markello, RD (author)
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Mathias, SR (author)
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Mazoyer, B (author)
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McGuire, P (author)
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Meaney, MJ (author)
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Mechelli, A (author)
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Medic, N (author)
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Misic, B (author)
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Morgan, SE (author)
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Mothersill, D (author)
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Nigg, J (author)
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Ong, MQW (author)
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Ortinau, C (author)
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- Ossenkoppele, R. (author)
- Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups
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Ouyang, M (author)
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Palaniyappan, L (author)
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Paly, L (author)
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Pan, PM (author)
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Pantelis, C (author)
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Park, MM (author)
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Paus, T (author)
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Pausova, Z (author)
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Paz-Linares, D (author)
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Binette, AP (author)
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Pierce, K (author)
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Qian, X (author)
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Qiu, J (author)
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Qiu, A (author)
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Raznahan, A (author)
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Rittman, T (author)
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Rodrigue, A (author)
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Rollins, CK (author)
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Romero-Garcia, R (author)
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Ronan, L (author)
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Rosenberg, MD (author)
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Rowitch, DH (author)
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Salum, GA (author)
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Satterthwaite, TD (author)
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Schaare, HL (author)
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Schachar, RJ (author)
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Schultz, AP (author)
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Schumann, G (author)
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Scholl, M (author)
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Sharp, D (author)
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Shinohara, RT (author)
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- Skoog, Ingmar, 1954 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Centrum för åldrande och hälsa (AgeCap),Institute of Neuroscience and Physiology,Centre for Ageing and Health (Agecap)
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Smyser, CD (author)
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Sperling, RA (author)
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Stein, DJ (author)
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Stolicyn, A (author)
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Suckling, J (author)
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Sullivan, G (author)
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Taki, Y (author)
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Thyreau, B (author)
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Toro, R (author)
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Traut, N (author)
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Tsvetanov, KA (author)
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Turk-Browne, NB (author)
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Tuulari, JJ (author)
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Tzourio, C (author)
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Vachon-Presseau, E (author)
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Valdes-Sosa, MJ (author)
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Valdes-Sosa, PA (author)
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Valk, SL (author)
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van Amelsvoort, T (author)
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Vandekar, SN (author)
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Vasung, L (author)
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Victoria, LW (author)
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Villeneuve, S (author)
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Villringer, A (author)
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Vertes, PE (author)
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Wagstyl, K (author)
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Wang, YS (author)
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Warfield, SK (author)
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Warrier, V (author)
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- Westman, E (author)
- Karolinska Institutet
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Westwater, ML (author)
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Whalley, HC (author)
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Witte, AV (author)
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Yang, N (author)
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Yeo, B (author)
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Yun, H (author)
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Zalesky, A (author)
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Zar, HJ (author)
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Zettergren, A (author)
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Zhou, JH (author)
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Ziauddeen, H (author)
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Zugman, A (author)
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Zuo, XN (author)
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Bullmore, ET (author)
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Alexander-Bloch, AF (author)
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R, Brain (author)
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show less...
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(creator_code:org_t)
- 2022-04-06
- 2022
- English.
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In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 604:79057906, s. 525-
- Related links:
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http://dx.doi.org/10... (free)
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http://kipublication...
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https://doi.org/10.1...
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Abstract
Subject headings
Close
- Over the past few decades, neuroimaging has become a ubiquitous tool in basic research and clinical studies of the human brain. However, no reference standards currently exist to quantify individual differences in neuroimaging metrics over time, in contrast to growth charts for anthropometric traits such as height and weight1. Here we assemble an interactive open resource to benchmark brain morphology derived from any current or future sample of MRI data (http://www.brainchart.io/). With the goal of basing these reference charts on the largest and most inclusive dataset available, acknowledging limitations due to known biases of MRI studies relative to the diversity of the global population, we aggregated 123,984 MRI scans, across more than 100 primary studies, from 101,457 human participants between 115 days post-conception to 100 years of age. MRI metrics were quantified by centile scores, relative to non-linear trajectories2 of brain structural changes, and rates of change, over the lifespan. Brain charts identified previously unreported neurodevelopmental milestones3, showed high stability of individuals across longitudinal assessments, and demonstrated robustness to technical and methodological differences between primary studies. Centile scores showed increased heritability compared with non-centiled MRI phenotypes, and provided a standardized measure of atypical brain structure that revealed patterns of neuroanatomical variation across neurological and psychiatric disorders. In summary, brain charts are an essential step towards robust quantification of individual variation benchmarked to normative trajectories in multiple, commonly used neuroimaging phenotypes.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Geriatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Geriatrics (hsv//eng)
Keyword
- anatomy and histology
- body height
- brain
- human
- longevity
- neuroimaging
- nuclear magnetic resonance imaging
- procedures
- Body Height
- Brain
- Humans
- Longevity
- Magnetic Resonance Imaging
- Neuroimaging
- psychiatric-disorders
- cortical thickness
- white-matter
- growth
- organization
- association
- disease
- mri
- burden
- models
- Science & Technology - Other Topics
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
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Nature
(Search for host publication in LIBRIS)
To the university's database
- By the author/editor
-
Bethlehem, RAI
-
Seidlitz, J
-
White, SR
-
Vogel, JW
-
Anderson, KM
-
Adamson, C
-
show more...
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Adler, S
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Alexopoulos, GS
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Anagnostou, E
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Areces-Gonzalez, ...
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Astle, DE
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Auyeung, B
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Ayub, M
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Bae, J
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Ball, G
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Baron-Cohen, S
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Beare, R
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Bedford, SA
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Benegal, V
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Beyer, F
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Blangero, J
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Cabez, MB
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Boardman, JP
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Borzage, M
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Bosch-Bayard, JF
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Bourke, N
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Calhoun, VD
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Chakravarty, MM
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Chen, C
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Chertavian, C
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Chetelat, G
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Chong, YS
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Cole, JH
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Corvin, A
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Costantino, M
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Courchesne, E
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Crivello, F
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Cropley, VL
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Crosbie, J
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Crossley, N
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Delarue, M
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Delorme, R
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Desrivieres, S
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Devenyi, GA
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Di Biase, MA
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Dolan, R
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Donald, KA
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Donohoe, G
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Dunlop, K
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Edwards, AD
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Elison, JT
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Ellis, CT
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Elman, JA
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Eyler, L
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Fair, DA
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Feczko, E
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Fletcher, PC
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Fonagy, P
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Franz, CE
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Galan-Garcia, L
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Gholipour, A
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Giedd, J
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Gilmore, JH
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Glahn, DC
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Goodyer, IM
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Grant, PE
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Groenewold, NA
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Gunning, FM
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Gur, RE
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Gur, RC
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Hammill, CF
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Hansson, O.
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Hedden, T
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Heinz, A
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Henson, RN
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Heuer, K
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Hoare, J
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Holla, B
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Holmes, AJ
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Holt, R
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Huang, H
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Im, K
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Ipser, J
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Jack, CR
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Jackowski, AP
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Jia, T
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Johnson, KA
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Jones, PB
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Jones, DT
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Kahn, RS
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Karlsson, H
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Karlsson, L
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Kawashima, R
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Kelley, EA
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Kern, Silke
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Kim, KW
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Kitzbichler, MG
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Kremen, WS
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Lalonde, F
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Landeau, B
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Lee, S
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Lerch, J
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Lewis, JD
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Li, J
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Liao, W
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Liston, C
-
Lombardo, MV
-
Lv, J
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Lynch, C
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Mallard, TT
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Marcelis, M
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Markello, RD
-
Mathias, SR
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Mazoyer, B
-
McGuire, P
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Meaney, MJ
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Mechelli, A
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Medic, N
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Misic, B
-
Morgan, SE
-
Mothersill, D
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Nigg, J
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Ong, MQW
-
Ortinau, C
-
Ossenkoppele, R.
-
Ouyang, M
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Palaniyappan, L
-
Paly, L
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Pan, PM
-
Pantelis, C
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Park, MM
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Paus, T
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Pausova, Z
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Paz-Linares, D
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Binette, AP
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Pierce, K
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Qian, X
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Qiu, J
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Qiu, A
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Raznahan, A
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Rittman, T
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Rodrigue, A
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Rollins, CK
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Romero-Garcia, R
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Ronan, L
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Rosenberg, MD
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Rowitch, DH
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Salum, GA
-
Satterthwaite, T ...
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Schaare, HL
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Schachar, RJ
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Schultz, AP
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Schumann, G
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Scholl, M
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Sharp, D
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Shinohara, RT
-
Skoog, Ingmar, 1 ...
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Smyser, CD
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Sperling, RA
-
Stein, DJ
-
Stolicyn, A
-
Suckling, J
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Sullivan, G
-
Taki, Y
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Thyreau, B
-
Toro, R
-
Traut, N
-
Tsvetanov, KA
-
Turk-Browne, NB
-
Tuulari, JJ
-
Tzourio, C
-
Vachon-Presseau, ...
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Valdes-Sosa, MJ
-
Valdes-Sosa, PA
-
Valk, SL
-
van Amelsvoort, ...
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Vandekar, SN
-
Vasung, L
-
Victoria, LW
-
Villeneuve, S
-
Villringer, A
-
Vertes, PE
-
Wagstyl, K
-
Wang, YS
-
Warfield, SK
-
Warrier, V
-
Westman, E
-
Westwater, ML
-
Whalley, HC
-
Witte, AV
-
Yang, N
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Yeo, B
-
Yun, H
-
Zalesky, A
-
Zar, HJ
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Zettergren, A
-
Zhou, JH
-
Ziauddeen, H
-
Zugman, A
-
Zuo, XN
-
Bullmore, ET
-
Alexander-Bloch, ...
-
R, Brain
-
show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Neurosciences
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Radiology Nuclea ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Neurology
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Geriatrics
- Articles in the publication
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Nature
- By the university
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Karolinska Institutet
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Lund University
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University of Gothenburg