The Role of Neutrophil-to-Lymphocyte Ratio in Risk Stratification and Prognostication of COVID-19: A Systematic Review and Meta-Analysis

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: WFRF:(Basavaraj CK) > (2022) > The Role of Neutrop...

1 of 1
Previous record
Next record
To hitlist

Details
MARC

Parthasarathi, A (author)

The Role of Neutrophil-to-Lymphocyte Ratio in Risk Stratification and Prognostication of COVID-19: A Systematic Review and Meta-Analysis

Article/chapterEnglish2022

Publisher, publication year, extent ...

2022-08-01
MDPI AG,2022

Numbers

LIBRIS-ID:oai:prod.swepub.kib.ki.se:150585722
http://kipublications.ki.se/Default.aspx?queryparsed=id:150585722URI
https://doi.org/10.3390/vaccines10081233DOI

Supplementary language notes

Language:English
Summary in:English

Part of subdatabase

SwePubSwePub

Classification

Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

Several studies have proposed that the neutrophil–lymphocyte ratio (NLR) is one of the various biomarkers that can be useful in assessing COVID-19 disease-related outcomes. Our systematic review analyzes the relationship between on-admission NLR values and COVID-19 severity and mortality. Six different severity criteria were used. A search of the literature in various databases was conducted from 1 January 2020 to 1 May 2021. We calculated the pooled standardized mean difference (SMD) for the collected NLR values. A meta-regression analysis was performed, looking at the length of hospitalization and other probable confounders, such as age, gender, and comorbidities. A total of sixty-four studies were considered, which included a total of 15,683 patients. The meta-analysis showed an SMD of 3.12 (95% CI: 2.64–3.59) in NLR values between severe and non-severe patients. A difference of 3.93 (95% CI: 2.35–5.50) was found between survivors and non-survivors of the disease. Upon summary receiver operating characteristics analysis, NLR showed 80.2% (95% CI: 74.0–85.2%) sensitivity and 75.8% (95% CI: 71.3–79.9%) specificity for the prediction of severity and 78.8% (95% CI: 73.5–83.2%) sensitivity and 73.0% (95% CI: 68.4–77.1%) specificity for mortality, and was not influenced by age, gender, or co-morbid conditions. Conclusion: On admission, NLR predicts both severity and mortality in COVID-19 patients, and an NLR > 6.5 is associated with significantly greater the odds of mortality.

Added entries (persons, corporate bodies, meetings, titles ...)

Padukudru, S (author)
Arunachal, S (author)
Basavaraj, CK (author)
Krishna, MT (author)
Ganguly, KKarolinska Institutet (author)
Upadhyay, SKarolinska Institutet (author)
Anand, MP (author)
Karolinska Institutet (creator_code:org_t)

Related titles

In:Vaccines: MDPI AG10:82076-393X

Internet link

Find in a library

Vaccines (Search for host publication in LIBRIS)

To the university's database

1 of 1
Previous record
Next record
To hitlist

Find more in SwePub

By the author/editor: Parthasarathi, A; Padukudru, S; Arunachal, S; Basavaraj, CK; Krishna, MT; Ganguly, K; show more...; Upadhyay, S; Anand, MP; show less...

Articles in the publication: Vaccines

By the university: Karolinska Institutet

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se