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Simultaneous Onset ...
Simultaneous Onset of Haematological Malignancy and COVID: An Epicovideha Survey
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Cattaneo, C (author)
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Salmanton-Garcia, J (author)
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Marchesi, F (author)
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show more...
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El-Ashwah, S (author)
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Itri, F (author)
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Weinbergerova, B (author)
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Da Silva, MG (author)
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Dargenio, M (author)
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Davila-Valls, J (author)
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Martin-Perez, S (author)
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Farina, F (author)
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Van Doesum, J (author)
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Valkovic, T (author)
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Besson, C (author)
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Poulsen, CB (author)
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Lopez-Garcia, A (author)
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Zak, P (author)
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Schonlein, M (author)
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Piukovics, K (author)
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Jaksic, O (author)
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Cabirta, A (author)
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Ali, N (author)
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Sili, U (author)
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Fracchiolla, N (author)
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Dragonetti, G (author)
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Adzic-Vukicevic, T (author)
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Marchetti, M (author)
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Machado, M (author)
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Glenthoj, A (author)
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Finizio, O (author)
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Demirkan, F (author)
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- Blennow, O (author)
- Karolinska Institutet
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Tisi, MC (author)
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Omrani, AS (author)
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Navratil, M (author)
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Racil, Z (author)
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Novak, J (author)
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Magliano, G (author)
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Jimenez, M (author)
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Garcia-Vidal, C (author)
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Erben, N (author)
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Del Principe, MI (author)
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Buquicchio, C (author)
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Bergantim, R (author)
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Batinic, J (author)
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Al-Khabori, M (author)
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Verga, L (author)
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Szotkowski, T (author)
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Samarkos, M (author)
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Ormazabal-Velez, I (author)
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Meers, S (author)
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Maertens, J (author)
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Pinczes, LI (author)
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Hoenigl, M (author)
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Drgona, L (author)
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Cuccaro, A (author)
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Bilgin, YM (author)
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Aujayeb, A (author)
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Rahimli, L (author)
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Grafe, S (author)
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Sciume, M (author)
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Mladenovic, M (author)
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Colak, GM (author)
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Sacchi, MV (author)
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- Nordlander, A (author)
- Karolinska Institutet
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Venemyr, CB (author)
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Hanakova, M (author)
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Garcia-Pouton, N (author)
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Emarah, Z (author)
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Zambrotta, GPM (author)
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Rodrigues, RN (author)
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Cordoba, R (author)
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Mendez, GA (author)
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Biernat, MM (author)
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Cornely, OA (author)
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Pagano, L (author)
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(creator_code:org_t)
- 2022-11-10
- 2022
- English.
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In: Cancers. - : MDPI AG. - 2072-6694. ; 14:22
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http://kipublication...
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https://doi.org/10.3...
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Abstract
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- Background: The outcome of patients with simultaneous diagnosis of haematological malignancies (HM) and COVID-19 is unknown and there are no specific treatment guidelines. Methods: We describe the clinical features and outcome of a cohort of 450 patients with simultaneous diagnosis of HM and COVID-19 registered in the EPICOVIDEHA registry between March 2020 to February 2022. Results: Acute leukaemia and lymphoma were the most frequent HM (35.8% and 35.1%, respectively). Overall, 343 (76.2%) patients received treatment for HM, which was delayed for longer than one month since diagnosis in 57 (16.6%). An overall response rate was observed in 140 (40.8%) patients after the first line of treatment. After a median follow-up of 35 days, overall mortality was 177/450 (39.3%); 30-day mortality was significantly higher in patients not receiving HM treatment (42.1%) than in those receiving treatment (27.4%, p = 0.004), either before and/or after COVID-19, or compared to patients receiving HM treatment at least after COVID-19 (15.2%, p < 0.001). Age, severe/critical COVID-19, ≥2 comorbidities, and lack of HM treatment were independent risk factors for mortality, whereas a lymphocyte count >500/mcl at COVID-19 onset was protective. Conclusions: HM treatment should be delivered as soon as possible for patients with simultaneous diagnosis of COVID-19 and HM requiring immediate therapy.
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- ref (subject category)
- art (subject category)
Find in a library
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Cancers
(Search for host publication in LIBRIS)
To the university's database
- By the author/editor
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Cattaneo, C
-
Salmanton-Garcia ...
-
Marchesi, F
-
El-Ashwah, S
-
Itri, F
-
Weinbergerova, B
-
show more...
-
Da Silva, MG
-
Dargenio, M
-
Davila-Valls, J
-
Martin-Perez, S
-
Farina, F
-
Van Doesum, J
-
Valkovic, T
-
Besson, C
-
Poulsen, CB
-
Lopez-Garcia, A
-
Zak, P
-
Schonlein, M
-
Piukovics, K
-
Jaksic, O
-
Cabirta, A
-
Ali, N
-
Sili, U
-
Fracchiolla, N
-
Dragonetti, G
-
Adzic-Vukicevic, ...
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Marchetti, M
-
Machado, M
-
Glenthoj, A
-
Finizio, O
-
Demirkan, F
-
Blennow, O
-
Tisi, MC
-
Omrani, AS
-
Navratil, M
-
Racil, Z
-
Novak, J
-
Magliano, G
-
Jimenez, M
-
Garcia-Vidal, C
-
Erben, N
-
Del Principe, MI
-
Buquicchio, C
-
Bergantim, R
-
Batinic, J
-
Al-Khabori, M
-
Verga, L
-
Szotkowski, T
-
Samarkos, M
-
Ormazabal-Velez, ...
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Meers, S
-
Maertens, J
-
Pinczes, LI
-
Hoenigl, M
-
Drgona, L
-
Cuccaro, A
-
Bilgin, YM
-
Aujayeb, A
-
Rahimli, L
-
Grafe, S
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Sciume, M
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Mladenovic, M
-
Colak, GM
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Sacchi, MV
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Nordlander, A
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Venemyr, CB
-
Hanakova, M
-
Garcia-Pouton, N
-
Emarah, Z
-
Zambrotta, GPM
-
Rodrigues, RN
-
Cordoba, R
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Mendez, GA
-
Biernat, MM
-
Cornely, OA
-
Pagano, L
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show less...
- Articles in the publication
-
Cancers
- By the university
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Karolinska Institutet