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Inflammaging and Bl...
Inflammaging and Blood Pressure Profiles in Late Life: The Screening for CKD among Older People across Europe (SCOPE) Study
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- Tap, L (author)
- University Medical Center Rotterdam, The Netherlands
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- Corsonello, A (author)
- Karolinska Institutet
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- Di Rosa, M (author)
- Italian National Research Center on Aging (INRCA), Ancona, Italy
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- Fabbietti, P (author)
- Italian National Research Center on Aging (INRCA), Ancona, Italy
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- Formiga, F (author)
- Bellvitge University Hospital-IDIBELL-L'Hospitalet de Llobregat, Barcelona, Spain
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- Moreno-Gonzalez, R (author)
- Bellvitge University Hospital-IDIBELL-L'Hospitalet de Llobregat, Barcelona, Spain
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- Ärnlöv, Johan, 1970- (author)
- Högskolan Dalarna,Karolinska Institutet,Medicinsk vetenskap,Karolinska Institutet, Stockholm, Sweden
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- Carlsson, AC (author)
- Karolinska Institutet
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- Polinder-Bos, HA (author)
- University Medical Center Rotterdam, The Netherlands
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Roller-Wirnsberger, RE (author)
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Wirnsberger, GH (author)
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Kostka, T (author)
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Guligowska, A (author)
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Artzi-Medvedik, R (author)
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Yehoshua, I (author)
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Weingart, C (author)
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Sieber, CC (author)
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Gil, P (author)
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Martinez, SL (author)
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Lattanzio, F (author)
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- Mattace-Raso, FUS (author)
- University Medical Center Rotterdam, The Netherlands
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(creator_code:org_t)
- 2022-12-09
- 2022
- English.
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In: Journal of clinical medicine. - : MDPI AG. - 2077-0383. ; 11:24
- Related links:
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https://doi.org/10.3...
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https://du.diva-port... (primary) (Raw object)
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Abstract
Subject headings
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- The neutrophil-to-lymphocyte ratio (NLR) is a marker for systemic inflammation. Since inflammation plays a relevant role in vascular aging, the aim of this study was to investigate whether NLR is associated with blood pressure profiles in older adults. This study was performed within the framework of the SCOPE study including 2461 outpatients aged 75 years and over. Mean blood pressure values, namely systolic blood pressure (SBP), diastolic blood pressure (DBP) and pulse pressure (PP) were investigated across tertiles of NLR. Change in blood pressure levels in 2 years of follow-up were compared across categories of baseline NLR. Data of 2397 individuals were used, of which 1854 individuals had hypertension. Mean values of blood pressure did not differ across categories of baseline NLR in individuals without hypertension. Individuals with hypertension with a high-range NLR had lower SBP and PP when compared to those in low-range NLR (mean difference SBP −2.94 mmHg, p = 0.032 and PP −2.55 mmHg, p = 0.030). Mean change in blood pressure in 2 years did only slightly differ in non-clinically relevant ranges, when compared across tertiles of baseline NLR. NLR as a marker of inflammaging was not associated with unfavorable blood pressure profiles in older individuals with or without hypertension.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Keyword
- blood pressure
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Tap, L
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Corsonello, A
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Di Rosa, M
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Fabbietti, P
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Formiga, F
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Moreno-Gonzalez, ...
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show more...
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Ärnlöv, Johan, 1 ...
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Carlsson, AC
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Polinder-Bos, HA
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Roller-Wirnsberg ...
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Wirnsberger, GH
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Kostka, T
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Guligowska, A
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Artzi-Medvedik, ...
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Yehoshua, I
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Weingart, C
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Sieber, CC
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Gil, P
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Martinez, SL
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Lattanzio, F
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Mattace-Raso, FU ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
- Articles in the publication
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Journal of clini ...
- By the university
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Karolinska Institutet
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Högskolan Dalarna