Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRASG12C with Demonstrable CNS Penetration

Kettle, JG (author)

Bagal, SK (author)

Barratt, D (author)

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Bodnarchuk, MS (author)

Boyd, S (author)

Braybrooke, E (author)

Breed, J (author)

Cassar, DJ (author)

Cosulich, S (author)

Davies, M (author)

Davies, NL (author)

Deng, C (author)

Eatherton, A (author)

Evans, L (author)

Feron, LJ (author)

Fillery, S (author)

Gleave, ES (author)

Goldberg, FW (author)

Gonzalez, MAC (author)

Karolinska Institutet

Guerot, C (author)

Haider, A (author)

Harlfinger, S (author)

Howells, R (author)

Jackson, A (author)

Johnstrom, P (author)

Kemmitt, PD (author)

Koers, A (author)

Kondrashov, M (author)

Lamont, GM (author)

Lamont, S (author)

Lewis, HJ (author)

Liu, LB (author)

Mylrea, M (author)

Nash, S (author)

Niedbala, MJ (author)

Peter, A (author)

Phillips, C (author)

Pike, K (author)

Raubo, P (author)

Robb, GR (author)

Ross, S (author)

Sanders, MG (author)

Schou, M (author)

Simpson, I (author)

Steward, O (author)

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 (creator_code:org_t)

2023

2023

English.

In: Journal of medicinal chemistry. - 1520-4804. ; 66:13, s. 9147-9160

Related links:

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• Journal article (peer-reviewed)