Search: (WFRF:(Fukami K)) srt2:(1995-1999) >
Effects of surgery ...
Effects of surgery on mucosal pathologic changes following experimental sinusitis in rabbit
-
Forsgren, K (author)
-
Westrin, KM (author)
-
Fukami, M (author)
-
show more...
-
- Stierna, P (author)
- Karolinska Institutet
-
show less...
-
(creator_code:org_t)
- 2016-06-28
- 1998
- English.
-
In: The Annals of otology, rhinology, and laryngology. - : SAGE Publications. - 0003-4894 .- 1943-572X. ; 107:2, s. 155-163
- Related links:
-
http://kipublication...
-
show more...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- In the present investigation, the regenerative capacity of the infected maxillary sinus mucosa following surgical procedures was studied in a rabbit model. Sinusitis was induced by occluding the ostium with and without the addition of Staphylococcus aureus or Bacteroides fragilis, or by provoking a prolonged bacterial infection with both pathogens. The surgical procedures performed were 1) widening of the natural sinus ostium (middle meatal antrostomy; MMA) and 2) removal of sinus mucosa without ostial interference (modified radical operation; MRO). The histologic features of the entire nose-sinus complex were studied, graded semiquantitatively, and compared with findings in untreated sinusitis, or after surgery only. Whereas MMA and MRO both led to a decrease of the inflammatory features of the sinus mucosa in induced sinusitis, persistent local histopathology was observed in the ostial region following MMA surgery. This indicates the importance of local pathologic changes resulting from interactions of bacterial colonization, inflammation, and surgery in chronic sinusitis.
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database