Low birth weight, family history of diabetes, and glucose intolerance in Swedish middle-aged men

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Sökning: WFRF:(GRILL V) > Low birth weight, f...

Carlsson, SKarolinska Institutet (författare)

Low birth weight, family history of diabetes, and glucose intolerance in Swedish middle-aged men

Artikel/kapitelEngelska1999

Förlag, utgivningsår, omfång ...

American Diabetes Association,1999

Nummerbeteckningar

LIBRIS-ID:oai:prod.swepub.kib.ki.se:1957482
http://kipublications.ki.se/Default.aspx?queryparsed=id:1957482URI
https://doi.org/10.2337/diacare.22.7.1043DOI

Kompletterande språkuppgifter

Språk:engelska
Sammanfattning på:engelska

Ingår i deldatabas

SwePubSwePub

Klassifikation

Ämneskategori:ref swepub-contenttype
Ämneskategori:art swepub-publicationtype

Anmärkningar

OBJECTIVE: To investigate the association between low birth weight and glucose intolerance in relation to family history of diabetes. RESEARCH DESIGN AND METHODS: We conducted a population-based cross-sectional study of 2,237 men born in 1938-1957 in four municipalities in the outskirts of Stockholm, 50% of whom had a family history of diabetes (at least one first-degree or two second-degree relatives with diabetes). Oral glucose tolerance testing detected 35 cases of type 2 diabetes, 102 cases of impaired glucose tolerance, and 57 cases of impaired fasting glucose. RESULTS: In subjects without a family history of diabetes, low (< or = 3,000 g) birth weight was associated with an odds ratio of 2.3 (95% confidence intervals = 0.4-14.4) for diabetes, 1.8 (0.7-4.3) for impaired glucose tolerance, and 3.3 (1.0-10.4) for impaired fasting glucose. In subjects with a family history of diabetes, the corresponding figures were approximately similar, except for diabetes, for which the odds ratio was 5.4 (2.0-14.9). For men with low birth weight in combination with a family history of diabetes, the odds ratio was 10.9 (2.9-41.2) for diabetes, 2.4 (1.1-5.6) for impaired glucose tolerance, and 5.9 (2.1-16.3) for impaired fasting glucose. CONCLUSIONS: This study indicated that low birth weight is associated with type 2 diabetes, impaired glucose tolerance, and impaired fasting glucose in men. This finding was most pronounced in subjects with diabetes in the family, but it was also indicated in those without a family history of diabetes. Men with the combination of low birth weight and family history of diabetes seem to be at particularly high risk of developing type 2 diabetes.

Biuppslag (personer, institutioner, konferenser, titlar ...)

Persson, PG (författare)
Alvarsson, MKarolinska Institutet (författare)
Efendic, S (författare)
Norman, A (författare)
Svanstrom, LKarolinska Institutet (författare)
Ostenson, CGKarolinska Institutet (författare)
Grill, V (författare)
Karolinska Institutet (creator_code:org_t)

Sammanhörande titlar

Ingår i:Diabetes care: American Diabetes Association22:7, s. 1043-10470149-59921935-5548

Internetlänk

Hitta via bibliotek

Diabetes care (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

Hitta mer i SwePub

Av författaren/redakt...: Carlsson, S; Persson, PG; Alvarsson, M; Efendic, S; Norman, A; Svanstrom, L; visa fler...; Ostenson, CG; Grill, V; visa färre...

Artiklar i publikationen: Diabetes care

Av lärosätet: Karolinska Institutet

Sök utanför SwePub

Sök vidare i:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se