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Effect of long-term...
Effect of long-term oxygen therapy on cognitive and neurological dysfunction in chronic obstructive pulmonary disease
- Article/chapterEnglish1999
Publisher, publication year, extent ...
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1999-07-06
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S. Karger AG,1999
Numbers
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LIBRIS-ID:oai:prod.swepub.kib.ki.se:1958917
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http://kipublications.ki.se/Default.aspx?queryparsed=id:1958917URI
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https://doi.org/10.1159/000008065DOI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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The aim of this study was to assess effect of long-term oxygen therapy (LTOT) on the function of central and autonomic nervous system in patients with hypoxaemic chronic obstructive pulmonary disease (COPD). A battery of neuropsychological tests was used together with the Short Test of Mental Status in addition to transcranial Doppler ultrasonography, and five cardiovascular tests as well as a questionnaire on autonomic function. Ten COPD patients, 4 males and 6 females, with a mean age of 65.9 ± 7.3 (SD) years, were studied at the beginning and after 3 months of LTOT. At start PaO<sub>2</sub> was 6.7 ± 1.1 kPa without oxygen and 9.9 ± 1.5 kPa after 3 months with oxygen. Our results demonstrate that neuropsychological function, cerebral blood flow velocity and autonomic function were positively influenced after 3 months of LTOT although the changes did not reach statistical significance. The COPD patients were cognitively impaired as compared to age-matched healthy controls. Our findings were consistent with the previous notion of improvement of hypoxic cognitive dysfunction by LTOT.
Added entries (persons, corporate bodies, meetings, titles ...)
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Waterloo, K
(author)
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Dahl, A
(author)
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Jorde, R
(author)
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Viitanen, MKarolinska Institutet
(author)
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Karolinska Institutet
(creator_code:org_t)
Related titles
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In:European neurology: S. Karger AG42:1, s. 27-350014-30221421-9913
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