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Home-Applied Dual-L...
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Pakarinen, S
(författare)
Home-Applied Dual-Light Photodynamic Therapy in the Treatment of Stable Chronic Periodontitis (HOPE-CP)-Three-Month Interim Results
- Artikel/kapitelEngelska2022
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LIBRIS-ID:oai:prod.swepub.kib.ki.se:236354651
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http://kipublications.ki.se/Default.aspx?queryparsed=id:236354651URI
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https://doi.org/10.3390/dj10110206DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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A single-site, randomized clinical trial was designed to determine the efficacy of regular home use of Lumoral® dual-light antibacterial aPDT in periodontitis patients. For the study, 200 patients were randomized to receive non-surgical periodontal treatment (NSPT), including standardized hygiene instructions and electric toothbrush, scaling and root planing, or NSPT with adjunctive Lumoral® treatment. A complete clinical intraoral examination was conducted in the beginning, at three months, and at six months. This report presents the three-month results of the first 59 consecutive randomized subjects. At three months, bleeding on probing (BOP) was lower in the NSPT + Lumoral®-group than in the NSPT group (p = 0.045), and more patients in the NSPT + Lumoral®-group had their BOP below 10% (54% vs. 22%, respectively, p = 0.008). In addition, patients in the NSPT + Lumoral®-group improved their oral hygiene by visible-plaque-index (p = 0.0003), while the NSPT group showed no statistical improvement compared to the baseline. Both groups significantly reduced the number of deep periodontal pockets, but more patients with a reduction in their deep pocket number were found in the NSPT + Lumoral® group (92% vs. 63%, p = 0.02). Patients whose number of deep pockets was reduced by 50% or more were also more frequent in the NSPT + Lumoral®-group (71% vs. 33%, p = 0.01). Patients with initially less than ten deep pockets had fewer deep pockets at the three-month follow-up in the Lumoral® group (p = 0.01). In conclusion, adjunctive use of Lumoral® in NSPT results in improved treatment outcomes at three months post-therapy.
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Saarela, RKT
(författare)
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Välimaa, H
(författare)
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Heikkinen, AM
(författare)
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Kankuri, E
(författare)
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Noponen, M
(författare)
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Alapulli, H
(författare)
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Tervahartiala, T
(författare)
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Räisänen, IT
(författare)
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Sorsa, TKarolinska Institutet
(författare)
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Pätilä, T
(författare)
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Karolinska Institutet
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Dentistry journal: MDPI AG10:112304-6767
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- Av författaren/redakt...
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Pakarinen, S
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Saarela, RKT
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Välimaa, H
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Heikkinen, AM
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Kankuri, E
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Noponen, M
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visa fler...
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Alapulli, H
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Tervahartiala, T
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Räisänen, IT
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Sorsa, T
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Pätilä, T
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visa färre...
- Artiklar i publikationen
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Dentistry journa ...
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Karolinska Institutet