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  • Bougas, KostasMalmö högskola,Odontologiska fakulteten (OD) (author)

Bone apposition to laminin-1 coated implants : Histologic and 3D evaluation

  • Article/chapterEnglish2013

Publisher, publication year, extent ...

  • Elsevier BV,2013
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:ri-13332
  • https://urn.kb.se/resolve?urn=urn:nbn:se:ri:diva-13332URI
  • https://doi.org/10.1016/j.ijom.2012.11.008DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-5879URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Laminin-1 has been reported as one of the factors responsible for the nucleation of calcium phosphates and, in vitro, has been reported to selectively recruit osteoprogenitors. This article focused on its in vivo effects, and evaluated the effect of laminin-1 local application on osseointegration. Polished cylindrical hydroxyapatite implants were coated with laminin-1 (test) and the bone responses in the rabbit tibiae after 2 and 4 weeks were evaluated and compared to the non-coated implants (control). Before the samples were processed for histological sectioning, they were three-dimensionally analysed with micro computed tomography (μCT). Both evaluation methods were analysed with regards to bone area around the implant and bone to implant contact. From the histologic observation, new bone formation around the laminin-1 coated implant at 2 weeks seemed to have increased the amount of supporting bone around the implant, however, at 4 weeks, the two groups presented no notable differences. The two-dimensional and three-dimensional morphometric evaluation revealed that both histologic and three-dimensional analysis showed some tendency in favour of the test group implants, however there was no statistical significance between the test and control group results.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Jimbo, RyoMalmö högskola,Odontologiska fakulteten (OD)(Swepub:mau)odryji (author)
  • Vandeweghe, StefanMalmö högskola,Odontologiska fakulteten (OD) (author)
  • Hayashi, MarikoMalmö högskola,Odontologiska fakulteten (OD)(Swepub:mau)odmaha (author)
  • Bryington, Matthew S.Malmö högskola,Odontologiska fakulteten (OD) (author)
  • Kozai, YusukeKanagawa Dental College, Japan (author)
  • Schwartz-Filho, Humberto OsvaldoSao Paulo State University, Brazil (author)
  • Tovar, Nick M.New York University, USA (author)
  • Adolfsson, ErikRISE,IVF (author)
  • Ono, DaisukeNagasaki University, Japan (author)
  • Coelho, Paulo GuilhermeNew York University, USA (author)
  • Wennerberg, AnnMalmö högskola,Odontologiska fakulteten (OD)(Swepub:mau)odanwe (author)
  • Malmö högskolaOdontologiska fakulteten (OD) (creator_code:org_t)

Related titles

  • In:International Journal of Oral and Maxillofacial Surgery: Elsevier BV42:5, s. 677-6820901-50271399-0020

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