Fourier analysis of cerebrospinal fluid flow velocities : MR imaging study

An interleaved pseudocinematographic FLASH (fast low-angle shot) sequence with additional pulsed gradients for flow encoding was used to quantify cerebrospinal fluid (CSF) flow velocities and CSF production. Flow-dependent phase information was obtained by subtracting two differently encoded phase images. The phase information in the resultant image was converted to flow velocity with a calibration curve with the slope 26.5 radian · m-1 · sec. The velocity versus time function was Fourier transformed and a continuous curve was fitted to the measured data with use of the first three harmonics. The in vivo measurements showed a significant variation in flow velocities in the cerebral aqueduct (range, 6-51 mm/ sec). Calculated CSF production was in the range of 0.6-1.2 L/24 h. The present method gives valuable information about CSF hydrodynamics in an imaging time of less than 8 minutes.

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Radiologi och bildbehandling hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Radiology, Nuclear Medicine and Medical Imaging hsv//eng
Cerebrospinal fluid, flow dynamics, 10.1214
Cerebrospinal fluid, MR studies, 10.1214
Magnetic resonance (MR), physics
Magnetic resonance (MR), pulse sequences
Phantoms

Ståhlberg, FreddyLund University,Lunds universitet,Diagnostisk radiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Medicinsk strålningsfysik, Lund,Institutionen för kliniska vetenskaper, Lund,MR Physics,Forskargrupper vid Lunds universitet,Diagnostic Radiology, (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Medical Radiation Physics, Lund,Department of Clinical Sciences, Lund,Lund University Research Groups(Swepub:lu)rafy-fst (author)
Stubgaard, M.Hvidovre Hospital (author)
Nordell, BoStockholm University (author)
Hvidovre HospitalDiagnostisk radiologi, Lund (creator_code:org_t)

In:Radiology: Radiological Society of North America (RSNA)177:3, s. 659-6650033-84191527-1315

By the author/editor: Thomsen, Carsten; Ståhlberg, Fredd ...; Stubgaard, M.; Nordell, Bo

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Radiology Nuclea ...

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