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A combined tactile ...
A combined tactile and Raman probe for tissue characterization - Design considerations
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- Nyberg, Morgan (författare)
- Luleå tekniska universitet,Signaler och system,Luleå tekniska universitet (LTU),Luleå University of Technology (LTU)
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- Candefjord, Stefan, 1981 (författare)
- Luleå tekniska universitet,Signaler och system,Department of Signals and Systems, Chalmers University of Technology, 412 96 Gothenburg, Sweden; MedTech West, Sahlgrenska University Hospital, Blå Stråket 7, 413 45 Gothenburg, Sweden,Chalmers tekniska högskola,Chalmers University of Technology
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- Jalkanen, Ville, 1978- (författare)
- Umeå universitet,Institutionen för tillämpad fysik och elektronik,Centrum för medicinsk teknik och fysik (CMTF),Department of Applied Physics and Electronics, Umeå University, 901 87 Umeå, Sweden,Luleå tekniska universitet (LTU),Luleå University of Technology (LTU),Umeå University
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- Ramser, Kerstin, 1964 (författare)
- Luleå tekniska universitet,Signaler och system,Luleå tekniska universitet (LTU),Luleå University of Technology (LTU)
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- Lindahl, Olof A (författare)
- Luleå tekniska universitet,Umeå universitet,Radiofysik,Signaler och system,Department of Radiation Sciences/Biomedical Engineering, Umeå University, 901 87 Umeå, Sweden,Luleå tekniska universitet (LTU),Luleå University of Technology (LTU),Umeå University
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(creator_code:org_t)
- 2012-05-04
- 2012
- Engelska.
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Ingår i: Measurement Science and Technology. - : IOP Publishing. - 0957-0233 .- 1361-6501. ; 23:6
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Abstract
Ämnesord
Stäng
- Histopathology is the golden standard for cancer diagnosis and involves the characterization of tissue components. It is labour intensive and time consuming. We have earlier proposed a combined fibre-optic near-infrared Raman spectroscopy (NIR-RS) and tactile resonance method (TRM) probe for detecting positive surgical margins as a complement to interoperative histopathology. The aims of this study were to investigate the effects of attaching an RS probe inside a cylindrical TRM sensor and to investigate how laser-induced heating of the fibre-optic NIR-RS affected the temperature of the RS probe tip and an encasing TRM sensor. In addition, the possibility to perform fibre-optic NIR-RS in a well-lit environment was investigated. A small amount of rubber latex was preferable for attaching the thin RS probe inside the TRM sensor. The temperature rise of the TRM sensor due to a fibre-optic NIR-RS at 270 mW during 20 s was less than 2 degrees C. Fibre-optic NIR-RS was feasible in a dimmed bright environment using a small light shield and automatic subtraction of a pre-recorded contaminant spectrum. The results are promising for a combined probe for tissue characterization.
Ämnesord
- NATURVETENSKAP -- Kemi -- Analytisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Analytical Chemistry (hsv//eng)
- NATURVETENSKAP -- Fysik -- Den kondenserade materiens fysik (hsv//swe)
- NATURAL SCIENCES -- Physical Sciences -- Condensed Matter Physics (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Annan medicinteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Other Medical Engineering (hsv//eng)
Nyckelord
- classification
- resonance sensor
- silicone
- optical-fiber probe
- subtraction
- thermal-stability
- stiffness
- spectroscopy
- in-vitro
- temperature
- tactile sensor
- Raman spectroscopy
- biological tissue
- Medical Engineering for Healthcare
- Centre - Centre for Biomedical Engineering and Physics (CMTF)
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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