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- Hong, Kuk-ki,1976Chalmers tekniska högskola,Chalmers University of Technology (author)
Metabolic Engineering of Saccharomyces cerevisiae: A Key Cell Factory Platform for Future Biorefineries
- Article/chapterEnglish2012
Publisher, publication year, extent ...
- 2012-03-03
- Springer Science and Business Media LLC,2012
Numbers
- LIBRIS-ID:oai:research.chalmers.se:5258c3af-ebfd-4980-ae7f-ffb9c514fca4
- https://research.chalmers.se/publication/158077URI
- https://doi.org/10.1007/s00018-012-0945-1DOI
Supplementary language notes
- Language:English
- Summary in:English
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- SwePubSwePub
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Notes
- Metabolic engineering is the enabling science of development of efficient cell factories for the production of fuels, chemicals, pharmaceuticals, and food ingredients through microbial fermentations. The yeast Saccharomyces cerevisiae is a key cell factory already used for the production of a wide range of industrial products, and here we review ongoing work, particularly in industry, on using this organism for the production of butanol, which can be used as biofuel, and isoprenoids, which can find a wide range of applications including as pharmaceuticals and as biodiesel. We also look into how engineering of yeast can lead to improved uptake of sugars that are present in biomass hydrolyzates, and hereby allow for utilization of biomass as feedstock in the production of fuels and chemicals employing S. cerevisiae. Finally, we discuss the perspectives of how technologies from systems biology and synthetic biology can be used to advance metabolic engineering of yeast.
Subject headings and genre
- TEKNIK OCH TEKNOLOGIER Industriell bioteknik hsv//swe
- ENGINEERING AND TECHNOLOGY Industrial Biotechnology hsv//eng
- NATURVETENSKAP Biologi Biokemi och molekylärbiologi hsv//swe
- NATURAL SCIENCES Biological Sciences Biochemistry and Molecular Biology hsv//eng
- TEKNIK OCH TEKNOLOGIER Industriell bioteknik Biokatalys och enzymteknik hsv//swe
- ENGINEERING AND TECHNOLOGY Industrial Biotechnology Biocatalysis and Enzyme Technology hsv//eng
- TEKNIK OCH TEKNOLOGIER Industriell bioteknik Annan industriell bioteknik hsv//swe
- ENGINEERING AND TECHNOLOGY Industrial Biotechnology Other Industrial Biotechnology hsv//eng
- Industrial biotechnology
- Isoprenoids
- Biobutanol
- Metabolic engineering
- Yeast Substrate range
Added entries (persons, corporate bodies, meetings, titles ...)
- Nielsen, Jens B,1962Chalmers tekniska högskola,Chalmers University of Technology(Swepub:cth)nielsenj (author)
- Chalmers tekniska högskola (creator_code:org_t)
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- In:Cellular and Molecular Life Sciences: Springer Science and Business Media LLC69:16, s. 2671-26901420-90711420-682X
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