Meso-ordered soft hydrogels

Claesson, Maria,1985Chalmers tekniska högskola,Chalmers University of Technology (author)

Many factors such as cross-link density are known to dictate the properties of hydrogels; however, less is known about the microstructure and how it can be tailored to control the properties. Here we demonstrate a method of forming microstructured hydrogels using a soft template that allows us to control and modify the microstructure. Meso-ordered hydrogels were formed by chemically cross-linking poly(ethylene glycol)-diacrylate (PEG-DA) segments via photopolymerization in the presence of poly(ethylene glycol)-poly(propylene glycol)-poly(ethylene glycol) (EOxPOyEOx) block copolymers. The results showed that hydrogels with lamellar mesostructured regions were formed when high concentrations of PEG-DA segments (50%) were used in combination with block co-polymers having certain ratios of the hydrophilic and hydrophobic blocks (P123, EO20PO70EO20). Only lamellar mesostructures were observed, independent of the PEG molecular weight (1500 or 3400 g mol(-1)) or block co-polymer concentration (10-50%). This finding demonstrates that it is possible to form soft meso-ordered hydrogels using block co-polymers as templates, and they do not follow the same mesophase behavior as the purely self-assembled block co-polymers.

Engberg, K.Stanford University (author)
Frank, C. W.Stanford University (author)
Andersson, Martin,1974Chalmers tekniska högskola,Chalmers University of Technology(Swepub:cth)martina (author)
Chalmers tekniska högskolaStanford University (creator_code:org_t)

In:Soft Matter: Royal Society of Chemistry (RSC)8:31, s. 8149-81561744-68481744-683X

By the author/editor: Claesson, Maria, ...; Engberg, K.; Frank, C. W.; Andersson, Marti ...

About the subject

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.