INetModels 2.0: An interactive visualization and database of multi-omics data

Arif, MuhammadKTH,Systembiologi,Science for Life Laboratory, SciLifeLab (författare)

QC 20210518
It is essential to reveal the associations between various omics data for a comprehensive understanding of the altered biological process in human wellness and disease. To date, very few studies have focused on collecting and exhibiting multi-omics associations in a single database. Here, we present iNetModels, an interactive database and visualization platform of Multi-Omics Biological Networks (MOBNs). This platform describes the associations between the clinical chemistry, anthropometric parameters, plasma proteomics, plasma metabolomics, as well as metagenomics for oral and gut microbiome obtained from the same individuals. Moreover, iNetModels includes tissue- and cancer-specific Gene Co-expression Networks (GCNs) for exploring the connections between the specific genes. This platform allows the user to interactively explore a single feature's association with other omics data and customize its particular context (e.g. male/female specific). The users can also register their data for sharing and visualization of the MOBNs and GCNs. Moreover, iNetModels allows users who do not have a bioinformatics background to facilitate human wellness and disease research. iNetModels can be accessed freely at https://inetmodels.com without any limitation.

Zhang, C.KTH,Science for Life Laboratory, SciLifeLab,Systembiologi,School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Zhengzhou University, Zhengzhou, Henan Province, PR 450001, China(Swepub:kth)u1ww5kvp (författare)
Li, XiangyuKTH,Systembiologi,Science for Life Laboratory, SciLifeLab(Swepub:kth)u1h6x89c (författare)
Güngör, Cem (författare)
Çakmak, Buǧra (författare)
Arslantürk, Metin (författare)
Tebani, AbdellahUniversite de Rouen,University of Rouen (författare)
Özcan, Berkay (författare)
Subaş, Oǧuzhan (författare)
Zhou, WenyuStanford University (författare)
Piening, B. D. (författare)
Turkez, HasanAtatürk Üniversitesi,Atatürk University (författare)
Fagerberg, LinnKTH,Science for Life Laboratory, SciLifeLab,Systembiologi(Swepub:kth)u1dglfid (författare)
Price, Nathan D. (författare)
Hood, Leroy (författare)
Snyder, Michael P.Stanford University (författare)
Nielsen, Jens B,1962Chalmers tekniska högskola,Chalmers University of Technology(Swepub:cth)nielsenj (författare)
Uhlén, MathiasKTH,Science for Life Laboratory, SciLifeLab,Systembiologi(Swepub:kth)u1dulvmw (författare)
Mardinoglu, Adil,1982KTH,Science for Life Laboratory, SciLifeLab,Systembiologi,Centre for Host–Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London SE1 9RT, UK(Swepub:kth)u1t8kmr6 (författare)
KTHSystembiologi (creator_code:org_t)

Ingår i:Nucleic Acids Research: Oxford University Press (OUP)49:W1, s. W271-W2760305-10481362-4962

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