Nanoplasmonic biosensing with on-chip electrical detection

Mazzotta, Francesco,1985Chalmers tekniska högskola,Chalmers University of Technology,Department of Applied Physics, Chalmers University of Technology, SE-41296 Gothenburg, Sweden (author)

A nanoplasmonic biosensor chip with integrated electrical detection is presented. The concept is based on the local refractive index sensitivity of nanoplasmonic gold nanodisks (110 nm in diameter and 20 nm in height) that are fabricated, through a parallel method, directly on an array of silicon solar cells or photoactive diodes. The nanoplasmonic properties of the sensor chip were investigated both optically and electrically, with excellent agreement between the two. We show that local changes in the refractive index of the surrounding environment gives changes in the nanoplasmonic properties of the gold nanodisks, which induce corresponding changes in the photocurrent at single wavelengths of the nanoplasmonic solar cells. With a simple light-emitting diode as light source, and together with a material-specific modification protocol, the photocurrent output of the nanoplasmonic sensor chip was successfully used to monitor a specific biorecognition reaction in real-time.

Wang, Guoliang,1965Chalmers tekniska högskola,Chalmers University of Technology,Department of Applied Physics, Chalmers University of Technology, SE-41296 Gothenburg, Sweden(Swepub:cth)guowa (author)
Hägglund, Carl,1975Chalmers tekniska högskola,Chalmers University of Technology,Department of Applied Physics, Chalmers University of Technology, SE-41296 Gothenburg, Sweden(Swepub:uu)carha577 (author)
Höök, Fredrik,1966Chalmers tekniska högskola,Chalmers University of Technology,Department of Applied Physics, Chalmers University of Technology, SE-41296 Gothenburg, Sweden(Swepub:cth)fredrikh (author)
Jonsson, Magnus,1981Chalmers tekniska högskola,Chalmers University of Technology,Department of Applied Physics, Chalmers University of Technology, SE-41296 Gothenburg, Sweden(Swepub:liu)magjo02 (author)
Chalmers tekniska högskolaDepartment of Applied Physics, Chalmers University of Technology, SE-41296 Gothenburg, Sweden (creator_code:org_t)

In:Biosensors and Bioelectronics: Elsevier BV26:4, s. 1131-11360956-56631873-4235

By the author/editor: Mazzotta, France ...; Wang, Guoliang, ...; Hägglund, Carl, ...; Höök, Fredrik, 1 ...; Jonsson, Magnus, ...

About the subject

NATURAL SCIENCES: NATURAL SCIENCES; and Chemical Science ...; and Analytical Chemi ...

NATURAL SCIENCES: NATURAL SCIENCES; and Physical Science ...; and Atom and Molecul ...

By the university: Chalmers University of Technology; Uppsala University; Linköping University

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.