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Understanding quali...
Understanding quality of life issues in patients with advanced melanoma: Phase 1 and 2 in the development of the EORTC advanced melanoma module
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- Egeler, M. D. (author)
- Netherlands Cancer Institute, Amsterdam, Netherlands
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- van Leeuwen, M. (author)
- Netherlands Cancer Institute, Amsterdam, Netherlands
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- Lai-Kwon, J. (author)
- Department of Medical Oncology and Department of Health Services Research, Peter MacCallum Cancer Centre, Melbourne, Australia
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- Eriksson, H. (author)
- Theme Cancer, Karolinska University Hospital, Stockholm, Sweden; Department of Oncology-Pathology, Karolinska Institutet, Sweden
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- Bartula, I. (author)
- Melanoma Institute Australia, The University of Sydney, Sydney, Australia
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- Elashwah, S. (author)
- Medical Oncology Unit, Oncology Center, Mansoura University (OCMU), Egypt
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- Fox, L. (author)
- King's College London, London, United Kingdom
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- Van Hemelrijck, M. (author)
- King's College London, London, United Kingdom
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- Jefford, M. (author)
- Department of Medical Oncology and Department of Health Services Research, Peter MacCallum Cancer Centre, Melbourne, Australia
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- Lijnsvelt, J. (author)
- Netherlands Cancer Institute, Department of Medical Oncology, Amsterdam, Netherlands
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- Lindqvist Bagge, Ann-Sophie (author)
- Gothenburg University,Göteborgs universitet,Sahlgrenska Centrum för Cancerforskning (SCCR),Psykologiska institutionen,Sahlgrenska Center for Cancer Research (SCCR),Department of Psychology,Sahlgrenska Center for Cancer Research, Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Psychology, University of Gothenburg, Gothenburg, Sweden
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- Morag, O. (author)
- Sheba Medical Center, The Jusjdman Cancer Center, Ramat-gan, Israel
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- Ny, Lars, 1967 (author)
- Gothenburg University,Göteborgs universitet,Sahlgrenska Centrum för Cancerforskning (SCCR),Sahlgrenska Center for Cancer Research (SCCR),Sahlgrenska Center for Cancer Research, Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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- Olofsson Bagge, Roger, 1978 (author)
- Gothenburg University,Göteborgs universitet,Sahlgrenska Centrum för Cancerforskning (SCCR),Sahlgrenska Center for Cancer Research (SCCR),Sahlgrenska Center for Cancer Research, Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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- Rogiers, A. (author)
- Department of Medical Oncology, Vrije Universiteit Brussel, Universitair Ziekenhuis Brussel, Brussels, Belgium
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- Saw, R. P.M. (author)
- Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, NSW, Sydney, Australia; Department of Melanoma and Surgical Oncology, Royal Prince Alfred Hospital, NSW, Sydney, Australia
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- Serpentini, S. (author)
- Veneto Institute of Oncology, Veneto, Italy
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- Iannopollo, L. (author)
- Veneto Institute of Oncology, Veneto, Italy
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- Thompson, J. (author)
- Melanoma Institute Australia, The University of Sydney, Sydney, Australia
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- Tufvesson Stiller, Helena (author)
- Umeå universitet,Institutionen för folkhälsa och klinisk medicin
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- Vanlaer, N. (author)
- Sheba Medical Center, The Jusjdman Cancer Center, Ramat-gan, Israel
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- van Akkooi, A. C.J. (author)
- Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, NSW, Sydney, Australia; Department of Melanoma and Surgical Oncology, Royal Prince Alfred Hospital, NSW, Sydney, Australia
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- van de Poll-Franse, L. V. (author)
- Netherlands Cancer Institute, Amsterdam, Netherlands
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(creator_code:org_t)
- Elsevier, 2024
- 2024
- English.
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In: European Journal of Cancer. - : Elsevier. - 0959-8049 .- 1879-0852. ; 207
- Related links:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Subject headings
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- Aims: We aimed to develop a European Organization for Research and Treatment of Cancer (EORTC) Quality of Life (QoL) module tailored for patients with advanced (resectable or unresectable stage III/IV) melanoma receiving immune checkpoint inhibitors or targeted therapy. Methods: Following the EORTC QoL Group module development guidelines, we conducted phases 1 and 2 of the development process. In phase 1, we generated a list of health-related (HR)QoL issues through a systematic literature review and semi-structured interviews with healthcare professionals (HCPs) and patients with advanced melanoma. In phase 2, these issues were converted into questionnaire items to create the preliminary module. Results: Phase 1: we retrieved 8006 articles for the literature review, of which 35 were deemed relevant, resulting in 84 HRQoL issues being extracted to create the initial issue list. Semi-structured interviews with 18 HCPs and 28 patients with advanced melanoma resulted in 28 issues being added to the initial issue list. Following EORTC module development criteria, 26 issues were removed, and two issues were added after review by patient advocates. Phase 2: To ensure uniformity and avoid duplication, 16 issues were consolidated into eight items. Additionally, an independent expert contributed one new item, resulting in a preliminary module comprising 80 HRQoL items. Conclusion: We identified a range of HRQoL issues (dry skin, xerostomia, and arthralgia) relevant to patients with stage III/IV melanoma. Future module development phases will refine the questionnaire. Once completed, this module will enable standardized assessment of HRQoL in patients with (locally) advanced melanoma.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- Melanoma
- Quality of life
- Melanoma
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Egeler, M. D.
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van Leeuwen, M.
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Lai-Kwon, J.
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Eriksson, H.
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Bartula, I.
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Elashwah, S.
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show more...
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Fox, L.
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Van Hemelrijck, ...
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Jefford, M.
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Lijnsvelt, J.
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Lindqvist Bagge, ...
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Morag, O.
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Ny, Lars, 1967
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Olofsson Bagge, ...
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Rogiers, A.
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Saw, R. P.M.
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Serpentini, S.
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Iannopollo, L.
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Thompson, J.
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Tufvesson Stille ...
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Vanlaer, N.
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van Akkooi, A. C ...
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van de Poll-Fran ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cancer and Oncol ...
- Articles in the publication
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European Journal ...
- By the university
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University of Gothenburg
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Umeå University