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Patient and tumour-...
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Wallerstedt, AnnaKarolinska Institutet
(författare)
Patient and tumour-related factors for prediction of urinary incontinence after radical prostatectomy.
- Artikel/kapitelEngelska2012
Förlag, utgivningsår, omfång ...
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2012-11-09
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Informa UK Limited,2012
Nummerbeteckningar
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LIBRIS-ID:oai:research.chalmers.se:8d9cf831-64ce-4d9b-90dd-293b61fdeb53
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https://doi.org/10.3109/00365599.2012.733410DOI
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https://research.chalmers.se/publication/168947URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:126960524URI
Kompletterande språkuppgifter
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Språk:engelska
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Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
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Ämneskategori:art swepub-publicationtype
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Ämneskategori:ref swepub-contenttype
Anmärkningar
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Abstract Objective. The aim of this study was to identify preoperative patient and tumour-related factors associated with 12 months postoperative urinary incontinence. Material and methods. In total, 1529 men who had undergone radical prostatectomy for clinically localized prostate cancer between September 2008 and February 2010 at 15 Swedish hospitals completed a questionnaire before, 3 and 12 months after surgery. Urinary leakage, comorbidity and possible confounders were measured by self-administered validated questionnaires. Clinical data were collected preoperatively and postoperatively. The primary outcome, incontinence, was defined as the change of one pad or more per day. The ratio of proportions, estimated according to the log-binomial regression model, was analysed for 38 different factors and is presented as relative risks with 95% confidence intervals. Age-adjusted relative risk was calculated in the corresponding bivariate regression model. Results. Prospective data were available from 1360 men (response rate 89%). Results showed that age at surgery predicts long-term urinary incontinence exponentially. Patients reporting urinary leakage before prostate cancer diagnosis had an age-adjusted relative risk of 1.8 (95% confidence interval 1.3-2.4) for incontinence 12 months postoperatively. No statistically significant correlation was found between previous transurethral resection of the prostate, high body mass index or the other 34 evaluated factors and postoperative incontinence. Conclusions. Of 38 possible risk factors only age at surgery and preoperative urinary leakage were associated with 12 months postoperative incontinence in this study comprising 1360 men operated with radical prostatectomy. These findings may help the surgeon to have a targeted risk conversation with the patient before the treatment decision is made.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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CARLSSON, STEFAN,1987Karolinska Institutet(Swepub:cth)stefanc
(författare)
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Steineck, Gunnar,1952Karolinska Institutet
(författare)
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Thorsteinsdottir, Thordis
(författare)
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Hugosson, Jonas,1955
(författare)
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Stranne, Johan,1970
(författare)
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Wilderäng, Ulrica
(författare)
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Haglind, Eva,1947
(författare)
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Wiklund, N PeterKarolinska Institutet
(författare)
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Karolinska Institutet
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Scandinavian Journal of Urology and Nephrology: Informa UK Limitedepub ahead1651-20650036-55992168-18052168-1813
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Till lärosätets databas
- Av författaren/redakt...
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Wallerstedt, Ann ...
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CARLSSON, STEFAN ...
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Steineck, Gunnar ...
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Thorsteinsdottir ...
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Hugosson, Jonas, ...
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Stranne, Johan, ...
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visa fler...
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Wilderäng, Ulric ...
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Haglind, Eva, 19 ...
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Wiklund, N Peter
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kirurgi
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Cancer och onkol ...
- Artiklar i publikationen
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Scandinavian Jou ...
- Av lärosätet
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Chalmers tekniska högskola
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Karolinska Institutet