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hsv:(MEDICAL AND HEALTH SCIENCES) hsv:(Medical Biotechnology) hsv:(Biomaterials Science)
 

Search: hsv:(MEDICAL AND HEALTH SCIENCES) hsv:(Medical Biotechnology) hsv:(Biomaterials Science) > Natural green coati...

  • Trentin, Danielle S (author)

Natural green coating inhibits adhesion of clinically important bacteria

  • Article/chapterEnglish2015

Publisher, publication year, extent ...

  • 2015-02-06
  • Nature Publishing Group,2015
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:umu-100278
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-100278URI
  • https://doi.org/10.1038/srep08287DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Despite many advances, biomaterial-associated infections continue to be a major clinical problem. In order to minimize bacterial adhesion, material surface modifications are currently being investigated and natural products possess large potential for the design of innovative surface coatings. We report the bioguided phytochemical investigation of Pityrocarpa moniliformis and the characterization of tannins by mass spectrometry. It was demonstrated that B-type linked proanthocyanidins-coated surfaces, here termed Green coatings, reduced Gram-positive bacterial adhesion and supported mammalian cell spreading. The proposed mechanism of bacterial attachment inhibition is based on electrostatic repulsion, high hydrophilicity and the steric hindrance provided by the coating that blocks bacterium-substratum interactions. This work shows the applicability of a prototype Green-coated surface that aims to promote necessary mammalian tissue compatibility, while reducing bacterial colonization.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Silva, Denise B (author)
  • Frasson, Amanda P (author)
  • Rzhepishevska, OlenaUmeå universitet,Kemiska institutionen(Swepub:umu)olrz0001 (author)
  • da Silva, Márcia V (author)
  • Pulcini, Elinor de L (author)
  • James, Garth (author)
  • Soares, Gabriel V (author)
  • Tasca, Tiana (author)
  • Ramstedt, MadeleineUmeå universitet,Kemiska institutionen(Swepub:umu)maerat95 (author)
  • Giordani, Raquel B (author)
  • Lopes, Norberto P (author)
  • Macedo, Alexandre J (author)
  • Umeå universitetKemiska institutionen (creator_code:org_t)

Related titles

  • In:Scientific Reports: Nature Publishing Group5, s. 8287-2045-2322

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