21-Deoxycortisone (17α-hydroxy-4-pregnene-3,11,20-trione)

Dey, Raja,1963Chalmers tekniska högskola,Chalmers University of Technology (författare)

The title compound, C21H28O4, a synthetic glucocorticoid, crystallizes with a single molecule in the asymmetric unit. Ring A is almost in a half-chair conformation, rings B and C are almost in chair conformations, and ring D is between a twist and a 13β-envelope conformation. The A/B ring junction is quasi-trans, whereas the B/C and C/D ring junctions both approach trans characteristics. The molecule as a whole is slightly convex towards the β side, with an angle of 9.60(2)° between the C10-C19 and C13-C18 vectors. Molecular-packing and hydrogen-bonding (both intra- and intermolecular) interactions play a major role in the structural association of the compound.

Langer, Vratislav,1949Chalmers tekniska högskola,Chalmers University of Technology(Swepub:cth)langer (författare)
Roychowdhury, P. (författare)
Roychowdhury, S. (författare)
Drew, M.G.B. (författare)
Chalmers tekniska högskola (creator_code:org_t)

Ingår i:Acta Crystallographica Section C: Crystal Structure CommunicationsC61:4, s. o201-o2030108-27011600-5759

Av författaren/redakt...: Dey, Raja, 1963; Langer, Vratisla ...; Roychowdhury, P.; Roychowdhury, S.; Drew, M.G.B.

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