Nanoparticles without and with protein corona: van der Waals and hydration interaction

• The van der Waals (vdW) interaction between nanoparticles (NPs) in general, and especially between metal NPs, may be appreciable, and may result in nanoparticle aggregation. In biofluids, NPs become rapidly surrounded by a protein corona (PC). Here, the vdW and hydration interaction of NPs with and without PC are compared in detail. The focus is on two widely used types of NPs fabricated of SiO2 and Au and possessing weak and strong vdW interactions, respectively. For SiO2, the presence of PC increases the vdW interaction, but it remains relatively weak and insufficient for aggregation. For Au, the presence of PC decreases the vdW interaction, and in the case of small NPs (≤ 40 nm in diameter) it may become insufficient for aggregation as well while the larger NPs can aggregate.

Ämnesord

NATURVETENSKAP  -- Kemi -- Fysikalisk kemi (hsv//swe)

NATURAL SCIENCES  -- Chemical Sciences -- Physical Chemistry (hsv//eng)

NATURVETENSKAP  -- Kemi -- Annan kemi (hsv//swe)

NATURAL SCIENCES  -- Chemical Sciences -- Other Chemistry Topics (hsv//eng)

NATURVETENSKAP  -- Biologi -- Biofysik (hsv//swe)

NATURAL SCIENCES  -- Biological Sciences -- Biophysics (hsv//eng)

Nyckelord

Nanoparticles

Aggregation

Nanoscience

Intermolecular forces

Publikations- och innehållstyp

art (ämneskategori)

ref (ämneskategori)