Search: WFRF:(Nyden Magnus)
> (2010-2014) >
Charged microcapsul...
Charged microcapsules for controlled release of hydrophobic actives Part II: Surface modification by LbL adsorption and lipid bilayer formation on properly anchored dispersant layers
-
- Andersson Trojer, Markus, 1981 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
-
- Li, Ye, 1986 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
-
- Wallin, Maria, 1985 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
-
show more...
-
- Holmberg, Krister, 1946 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
-
- Nydén, Magnus, 1970 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
-
show less...
-
(creator_code:org_t)
- Elsevier BV, 2013
- 2013
- English.
-
In: Journal of Colloid and Interface Science. - : Elsevier BV. - 1095-7103 .- 0021-9797. ; 409, s. 8-17
- Related links:
-
http://dx.doi.org/10...
-
show more...
-
https://doi.org/10.1...
-
https://research.cha...
-
show less...
Abstract
Subject headings
Close
- Charge microcapsules with a dodecane core and a poly(methyl methacrylate) (PMMA) shell have been prepared via the internal phase separation method using ionic dispersants. The microcapsules have subsequently been surface modified with polyelectrolyte multilayers and lipid bilayers. Two types of ionic dispersant systems have been investigated: a small set of ionic amphiphilic block copolymers of poly(methyl methacrylate)-block-poly(sodium (meth)acrylate) type and an oil-soluble anionic surfactant, sodium 1,5-dioxo-1,5-bis(3,5,5-trimethylhexyloxy)-3((3,5,5trimethylhexyloxy)car bonyl)pentane-2-sulfonate, in combination with a water-soluble polycation, poly(diallyldimethylammonium chloride). The Layer-by-Layer adsorption of the polyelectrolyte pair poly(diallydimethylammonium chloride) (350,000 g/mol) and poly(sodium methacrylate) (15,000 g/mol) was successfully made on both microcapsule systems with the formation of very thin multilayers as indicated with quartz crystal microbalance with dissipation monitoring (QCM-D) measurements on model surfaces. Formation of a lipid bilayer on the surface of the microcapsules from liposomes with a charge opposite that of the capsule surface was also proven to be successful as indicated by the C-potential of the microcapsules, the characteristic frequency shift as measured with QCM-D and fluorescence recovery after photobleaching (FRAP) on model systems. However, the proper anchorage of the dispersants in the underlying PMMA surface was key for the successful surface modification.
Subject headings
- NATURVETENSKAP -- Kemi -- Fysikalisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Physical Chemistry (hsv//eng)
Keyword
- encapsulation
- electrostatic interactions
- diffusion
- Lipid vesicle
- vesicle adsorption
- Quartz crystal microbalance with dissipation monitoring
- shell microcapsules
- Core-shell particle
- emulsion droplets
- colloidal particles
- internal phase-separation
- Liposome
- sustained-release
- polyelectrolyte multilayer capsules
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
To the university's database