Search: WFRF:(Hultin Jäderlund Karin) >
Poisoning of dogs w...
Poisoning of dogs with tremorgenic Penicillium toxins
-
- Sundstøl Eriksen, Gunnar (author)
- Norwegian Veterinary Institute
-
- Hultin Jäderlund, Karin (author)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences
-
(creator_code:org_t)
-
- Oxford University Press (OUP), 2010
- 2010
- English.
-
In: Medical Mycology. - : Oxford University Press (OUP). - 1369-3786 .- 1460-2709. ; 48, s. 188-196
- Related links:
-
https://academic.oup...
-
show more...
-
https://res.slu.se/i...
-
https://doi.org/10.3...
-
show less...
Abstract
Subject headings
Close
- Fungi in the genus Penicillium, particularly P. crustosum, produce tremorgenic mycotoxins, as well as suspected tremorgenic compounds. The accidental intoxication of six dogs with such toxins are reported. The clinical signs included vomiting, convulsions, tremors, ataxia, and tachycardia, all of which are indicators of intoxications affecting the nervous system. This symptomatology caused us to think that the dog poisoning was the result of tremorgenic mycotoxins. One dog was euthanized in the acute phase, while three others recovered completely within a few days. However, neurological symptoms were still observed four months after the poisoning of two of the dogs. One of these recovered completely within the next 2-3 months, while the other still suffers from ataxia three years later. Available samples of feed, stomach content and/or tissues from the intoxications were subjected to mycological and chemical analysis. Penitrem A was found in all reported poisonings and roquefortine C in all cases when this toxin was included in the analysis. The producer of these toxins, Penicillium crustosum, was detected in all cases where material suitable for mycological examinations (feed or vomit) was available. To our knowledge, this is the first report documenting the presence of penitrems and roquefortine C in organs from poisoned dogs. Furthermore, the report indicates that the recovery period after severe poisonings with P crustosum may be protracted.
Subject headings
- LANTBRUKSVETENSKAPER -- Veterinärmedicin -- Annan veterinärmedicin (hsv//swe)
- AGRICULTURAL SCIENCES -- Veterinary Science -- Other Veterinary Science (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database