id:"swepub:oai:slubar.slu.se:64950"
Sökning: id:"swepub:oai:slubar.slu.se:64950" > Increased concentra...
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
- Jitpean, SupraneeSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences (författare)
Increased concentrations of Serum amyloid A in dogs with sepsis caused by pyometra
- Artikel/kapitelEngelska2014
Förlag, utgivningsår, omfång ...
- 2014-11-28
- Springer Science and Business Media LLC,2014
- BioMed Central,2024
Nummerbeteckningar
- LIBRIS-ID:oai:slubar.slu.se:64950
- https://res.slu.se/id/publ/64950URI
- https://doi.org/10.1186/s12917-014-0273-9DOI
Kompletterande språkuppgifter
- Språk:engelska
- Sammanfattning på:engelska
Ingår i deldatabas
- SwePubSwePub
Klassifikation
Anmärkningar
- Background: Sepsis is a serious and potentially life-threatening condition and early diagnosis and appropriate treatment is crucial for survival. Pyometra is one of the most common diseases in intact female dogs. The disease often leads to sepsis (systemic inflammatory response syndrome, SIRS, caused by infection). Diagnostic markers for detecting sepsis are gaining increasing interest in veterinary medicine. Acute phase proteins (APPs) such as C-reactive protein (CRP) are useful for detecting systemic inflammation in dogs. Serum amyloid A (SAA) is another major APP in dogs that is not yet as widely used. Albumin is regarded as a negative APP and has earlier been evaluated for prediction of prognosis in septic dogs. The aim of the present study was to determine SAA, CRP and albumin concentrations in dogs with sepsis and pyometra and to evaluate whether these inflammatory markers are associated with length of postoperative hospitalization.Results: Thirty-one surgically treated bitches with pyometra were included, whereof 23 septic (SIRS-positive) and eight non-septic (SIRS-negative). Albumin concentrations were analyzed by routine automated methods. SAA and CRP analyses were performed with previously validated commercially available assays (ELISA and immunoturbidimetric). Mean (+/- SE) serum concentrations of SAA were significantly higher in septic (130.8 +/- 8.0 mg/L) compared to non-septic bitches (88.5 +/- 12.5 mg/L). Using a cut-off value for SAA of 109.07 mg/L (n = 31 bitches), the sensitivity and specificity for detecting sepsis was 74% and 50%, respectively. Serum albumin concentrations were not significantly different in septic compared to non-septic bitches (mean +/- SE, 25 +/- 1 g/L and 26 +/- 1 g/L, respectively). CRP concentrations were also not significantly different in septic (mean +/- SE 225.6 +/- 16.0 mg/L) compared to non-septic bitches (mean +/- SE, 176.0 +/- 27.1 mg/L). None of these inflammatory markers were associated with the outcome as measured by length of hospitalization.Conclusions: SAA concentrations were increased in dogs with sepsis induced by pyometra and may be useful as an adjunctive diagnostic marker for sepsis. To evaluate the full potential of SAA as a marker for sepsis also in other diseases, further studies are warranted.
Ämnesord och genrebeteckningar
- LANTBRUKSVETENSKAPER Veterinärmedicin Klinisk vetenskap hsv//swe
- AGRICULTURAL SCIENCES Veterinary Science Clinical Science hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Infektionsmedicin hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Infectious Medicine hsv//eng
- LANTBRUKSVETENSKAPER Veterinärmedicin Patobiologi hsv//swe
- AGRICULTURAL SCIENCES Veterinary Science Pathobiology hsv//eng
- LANTBRUKSVETENSKAPER Veterinärmedicin Annan veterinärmedicin hsv//swe
- AGRICULTURAL SCIENCES Veterinary Science Other Veterinary Science hsv//eng
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Pettersson, AnnSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences(Swepub:slu)49696 (författare)
- Höglund, OddSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences(Swepub:slu)50579 (författare)
- Ström Holst, BodilSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences(Swepub:slu)47321 (författare)
- Olsson, UlfSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för ekonomi,Department of Economics(Swepub:slu)51184 (författare)
- Hagman, RagnviSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences(Swepub:slu)50755 (författare)
- Sveriges lantbruksuniversitetInstitutionen för kliniska vetenskaper (KV) (creator_code:org_t)
- Sveriges lantbruksuniversitet
Sammanhörande titlar
- Ingår i:BMC Veterinary Research: Springer Science and Business Media LLC101746-6148
Internetlänk
Hitta via bibliotek
- BMC Veterinary Research (Sök värdpublikationen i LIBRIS)
Till lärosätets databas
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
Hitta mer i SwePub
- Av författaren/redakt...
- Jitpean, Suprane ...
- Pettersson, Ann
- Höglund, Odd
- Ström Holst, Bod ...
- Olsson, Ulf
- Hagman, Ragnvi
- Om ämnet
-
- LANTBRUKSVETENSKAPER
- LANTBRUKSVETENSK ...
- och Veterinärmedicin
- och Klinisk vetenska ...
-
- MEDICIN OCH HÄLSOVETENSKAP
- MEDICIN OCH HÄLS ...
- och Klinisk medicin
- och Infektionsmedici ...
-
- LANTBRUKSVETENSKAPER
- LANTBRUKSVETENSK ...
- och Veterinärmedicin
- och Patobiologi
-
- LANTBRUKSVETENSKAPER
- LANTBRUKSVETENSK ...
- och Veterinärmedicin
- och Annan veterinärm ...
- Artiklar i publikationen
- BMC Veterinary R ...
- Av lärosätet
- Sveriges Lantbruksuniversitet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
