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- Muzila, MbakiSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för växtförädling,Department of Plant Breeding,Swedish University Of Agricultural Sciences,Sveriges lantbruksuniversitet, Balsgård (author)
Alteration of Neutrophil Reactive Oxygen Species Production by Extracts of Devil’s Claw (Harpagophytum)
- Article/chapterEnglish2016
Publisher, publication year, extent ...
- Hindawi Limited,2016
Numbers
- LIBRIS-ID:oai:slubar.slu.se:76802
- https://res.slu.se/id/publ/76802URI
- https://doi.org/10.1155/2016/3841803DOI
- oai:researchportal.hkr.se/admin:publications/e84daf72-3a9b-43ec-aeb2-91a1ce1e7a26URI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- Harpagophytum,Devil’sClaw, is a genus of tuberiferous xerophytic plants native to southernAfrica. Some of the taxa are appreciated for their medicinal effects and have been traditionally used to relieve symptoms of inflammation.The objectives of this pilot study were to investigate the antioxidant capacity and the content of total phenols, verbascoside, isoverbascoside, and selected iridoids, as well as to investigate the capacity of various Harpagophytum taxa in suppressing respiratory burst in terms of reactive oxygen species produced by human neutrophils challenged with phorbol myristate acetate (PMA), opsonised Staphylococcus aureus, and Fusobacterium nucleatum. Harpagophytum plants were classified into different taxa according to morphology, and DNA analysis was used to confirmthe classification. A putative new variety of H. procumbens showed the highest degree of antioxidative capacity. Using PMA, three Harpagophytum taxa showed anti-inflammatory effects with regard to the PBS control. A putative hybrid between H. procumbens and H. zeyheri in contrast showed proinflammatory effect on the response of neutrophils to F. nucleatum in comparison with treatment with vehicle control. Harpagophytum taxa were biochemically very variable and the response in suppressing respiratory burst differed. Further studies with larger number of subjects are needed to corroborate anti-inflammatory effects of different taxa of Harpagophytum.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Annan hälsovetenskap hsv//swe
- MEDICAL AND HEALTH SCIENCES Health Sciences Other Health Sciences hsv//eng
- NATURVETENSKAP Biologi Botanik hsv//swe
- NATURAL SCIENCES Biological Sciences Botany hsv//eng
- NATURVETENSKAP Kemi Organisk kemi hsv//swe
- NATURAL SCIENCES Chemical Sciences Organic Chemistry hsv//eng
Added entries (persons, corporate bodies, meetings, titles ...)
- Rumpunen, KimmoSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för växtförädling,Department of Plant Breeding,Swedish University Of Agricultural Sciences,Sveriges lantbruksuniversitet, Balsgård(Swepub:slu)49096 (author)
- Sehic, JasnaSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för växtförädling,Department of Plant Breeding,Swedish University Of Agricultural Sciences,Sveriges lantbruksuniversitet, Balsgård(Swepub:slu)50213 (author)
- Ekholm, AndersSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för växtförädling,Department of Plant Breeding,Swedish University Of Agricultural Sciences,Sveriges lantbruksuniversitet, Balsgård(Swepub:slu)49832 (author)
- Widen, CeciliaKristianstad University(Swepub:slu)52767 (author)
- Nybom, HildeSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för växtförädling,Department of Plant Breeding,Swedish University Of Agricultural Sciences,Sveriges lantbruksuniversitet, Balsgård(Swepub:slu)48806 (author)
- Wright, HelenUnited Kingdom,Storbritannien (author)
- Roberts, HelenUnited Kingdom,Storbritannien (author)
- Grant, MelissaUnited Kingdom,Storbritannien (author)
- Sveriges lantbruksuniversitetInstitutionen för växtförädling (creator_code:org_t)
- Sveriges lantbruksuniversitet
Related titles
- In:Oxidative Medicine and Cellular Longevity: Hindawi Limited1942-09001942-0994
Internet link
- http://downloads.hindawi.com/journals/omcl/2016/3841803.pdf
- https://researchportal.hkr.se/ws/files/40825849/FULLTEXT01.pdfFULLTEXT
- https://doi.org/10.1155/2016/3841803FULLTEXT
- https://res.slu.se/id/publ/76802
- https://doi.org/10.1155/2016/3841803
- oai:researchportal.hkr.se/admin:publications/e84daf72-3a9b-43ec-aeb2-91a1ce1e7a26
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