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Comparison of a custom-made and a thermoplastic oral appliance for the treatment of mild sleep apnea

Vanderveken, Olivier M (author)
Devolder, Annick (author)
Umeå universitet,Ortodonti
Marklund, Marie (author)
Umeå universitet,Institutionen för odontologi
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Boudewyns, An N (author)
Braem, Marc J (author)
Okkerse, Walter (author)
Verbraecken, Johan A (author)
Franklin, Karl (author)
Umeå universitet,Lungmedicin,Kirurgi
De Backer, Wilfried A (author)
Van de Heyning, Paul H (author)
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 (creator_code:org_t)
New York : American Lung Association, 2008
2008
English.
In: American Journal of Respiratory and Critical Care Medicine. - New York : American Lung Association. - 1073-449X .- 1535-4970. ; 178:2, s. 197-202
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Rationale: The efficacy of immediate adaptation of mandibular advancement devices made of thermoplastic material as a treatment option for sleep-disordered breathing (SDB) has been demonstrated in clinical studies. To date, there have been no studies comparing the efficacy of such prefabricated devices with custom-made devices. Objectives: Our purpose was to compare the efficacy of both types of devices in patients with SDB. Methods: A randomized controlled cross-over trial, comprising 4 months of treatment with a thermoplastic and a custom-made device, with a 1-month washout interval. Measurements and Main Results: A total of 35 patients (29 males; age, 49 ± 9 yr; apnea–hypopnea index [AHI], 13 ± 11 events/h; body mass index, 28 ± 4 kg/m2) completed the protocol. AHI was only reduced with the custom-madedevice (P = 0.005). In addition, this device reduced snoring to a greater extent than the thermoplastic device. The success rate was higher with the custom-made device (60 vs. 31%; P = 0.02). One-third of the patients demonstrated compliance failure with the thermoplastic device, mainly because of insufficient overnight retention. Total failure rate with the thermoplastic device was 69%, whereas the majority (63%) of these were successfully treated with the custom-made device. At the end of the study, 82% of the patients preferred the custom-made device, and 9% had no preference (P < 0.0001). Conclusions: In this study, a custom-made device turned out to be more effective than a thermoplastic device in the treatment of SDB. Our results suggest that the thermoplastic device cannot be recommended as a therapeutic option nor can it be used as a screening tool to find good candidates for mandibular advancement therapy.

Keyword

excessive somnolence
oral appliances
polysomnography
sleep apnea
snoring

Publication and Content Type

ref (subject category)
art (subject category)

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